机构

• 上海药物研究所 [70]

采集方式

• OAI收割 [70]

内容类型

• 期刊论文 [70]

发表日期

• 2024 [1]
• 2023 [3]
• 2022 [9]
• 2021 [4]
• 2020 [6]
• 2019 [7]
• 更多

学科主题

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浏览/检索结果: 共70条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Structure-Guided Design, Synthesis, and Antivirulence Assessment of Covalent Staphylococcus aureus Sortase A Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1127-1146 作者:  Yue, Chuan;  Yuan, Ziqi;  Xu, Guobin;  Guan, Xiang-Na   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/02/27 A facile and selective derivatization approach on kynurenine-NH2 in daptomycin, leading to the discovery of hexakynomycin to combat multidrug-resistant Gram-positive pathogens especially daptomycin-resistant bacteria 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 14 作者:  Guan, Dongliang;  Li, Jian;  Chen, Feifei;  Li, Jiaqi;  Bian, Xiaolei   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/10/17 Lipopeptide  Daptomycin derivatives  Multidrug-resistant bacteria  Kynurenine  Hexakynomycin   Carbohydrate Strengthens the Immunotherapeutic Effect of Small-Molecule PD-L1 Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 11, 页码: 7179-7204 作者:  Dong, Qian;  Tong, Mengya;  Yu, Xiaolu;  Wang, Lei;  Ao, Jiwei   |  收藏  |  浏览/下载：15/0  |  提交时间：2023/10/17 Single Modification at the N-Terminus of Norvancomycin to Combat Drug-Resistant Gram-Positive Bacteria 期刊论文  OAI收割 CHEMMEDCHEM, 2023, 卷号: 18, 期号: 9 作者:  Guan, Dongliang;  Chen, Feifei;  Shi, Wei;  Lan, Lefu;  Huang, Wei   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/03/27 norvancomycin  glycopeptide antibiotics  single modification  sulfonium  bacterial resistance   Phonerilins A-K, cytotoxic ingenane and ingol diterpenoids from Euphorbia neriifolia 期刊论文  OAI收割 TETRAHEDRON, 2022, 卷号: 123, 页码: 9 作者:  Gao, Yuan;  Zhou, Jun-Su;  Liu, Hong-Chun;  Zhang, Yan;  Yin, Wei-Hang   |  收藏  |  浏览/下载：25/0  |  提交时间：2022/12/13 Euphorbia neriifolia  Diterpenoid  Ingenane  Ingol  Phonerilins A-K  Cytotoxicity   The allosteric gating mechanism of the MthK channel 期刊论文  OAI收割 NATIONAL SCIENCE REVIEW, 2022, 卷号: 9, 期号: 8, 页码: 12 作者:  Guan, Fenghui;  Li, Tianyu;  Dong, Wei;  Guo, Rui;  Chai, Hao   |  收藏  |  浏览/下载：25/0  |  提交时间：2022/09/30 ion channel  allosteric gating mechanism  protein structural data analysis   Loss of SIRT5 promotes bile acid-induced immunosuppressive microenvironment and hepatocarcinogenesis 期刊论文  OAI收割 JOURNAL OF HEPATOLOGY, 2022, 卷号: 77, 期号: 2, 页码: 453-466 作者:  Sun, Renqiang;  Zhang, Zhiyong;  Bao, Ruoxuan;  Guo, Xiaozhen;  Gu, Yuan   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/03/21 SIRT5  bile acid  macrophage polarization  immunosuppressive tumor microenvironment  liver cancer   Hemin protects against Zika virus infection by disrupting virus-endosome fusion 期刊论文  OAI收割 ANTIVIRAL RESEARCH, 2022, 卷号: 203, 页码: 11 作者:  Xu, Meng-Meng;  Wu, Bing;  Huang, Guan-Gen;  Feng, Chun-Lan;  Wang, Xiao-Han   |  收藏  |  浏览/下载：31/0  |  提交时间：2022/08/16 Zika virus  Hemin  Antiviral  Inflammation  HO-1  Viral fusion   Concise Total Synthesis of Dysoxylactam A and a Simplified Analog 期刊论文  OAI收割 CHINESE JOURNAL OF CHEMISTRY, 2022, 页码: 8 作者:  Yang, Guan-Zhou;  Wang, Lei;  Fan, Yao-Yue;  Lai, Zeng-Wei;  Yu, Xue-Ni   |  收藏  |  浏览/下载：23/0  |  提交时间：2022/08/16 Total synthesis  Dysoxylactam A  Macrocyclolipopeptide  Reversing multidrug resistance  Structure-activity relationship   Potentiation of Vancomycin: Creating Cooperative Membrane Lysis through a "Derivatization-for-Sensitization" Approach 期刊论文  OAI收割 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2022, 卷号: 144, 期号: 23, 页码: 10622-10639 作者:  Lei, E.;  Tao, Huanyu;  Jiao, Shang;  Yang, Anming;  Zhou, Yu   |  收藏  |  浏览/下载：26/0  |  提交时间：2022/08/16