机构

• 上海药物研究所 [240]

采集方式

• OAI收割 [240]

内容类型

• 期刊论文 [235]
• 专利 [3]
• 会议论文 [2]

发表日期

• 2024 [10]
• 2023 [27]
• 2022 [24]
• 2021 [22]
• 2020 [11]
• 2019 [12]
• 更多

学科主题

• Chemistry [3]
• Pharmacolo... [3]
• Biochemist... [1]
• Plant Scie... [1]

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浏览/检索结果: 共240条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Machine learning prediction for constructing a universal multidimensional information library of Panax saponins (ginsenosides) 期刊论文  OAI收割 FOOD CHEMISTRY, 2024, 卷号: 439, 页码: 10 作者:  Wang, Hongda;  Zhang, Lin;  Li, Xiaohang;  Sun, Mengxiao;  Jiang, Meiting   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/02/19 Retention time  Collision cross section  Machine learning  Multidimensional information library  Hierarchical design   Zinc finger protein ZNF638 regulates triglyceride metabolism via ANGPTL8 in an estrogen dependent manner 期刊论文  OAI收割 METABOLISM-CLINICAL AND EXPERIMENTAL, 2024, 卷号: 152, 页码: 12 作者:  Meng, Meiyao;  Cao, Yuxiang;  Qiu, Jin;  Shan, Guangyu;  Wang, Yingwen   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/03/25 Triglyceride metabolism  ZNF638  Adipose tissue  Angptl8  Lipoprotein lipase   Activating CD8+ T Cells by Pt(IV) Prodrug-Based Nanomedicine and aPD-L1 Antibody for Enhanced Cancer Immunotherapy 期刊论文  OAI收割 ADVANCED MATERIALS, 2024, 页码: 15 作者:  Wang, Bin;  Zhou, Jingyu;  Li, Ruitong;  Tang, Dongsheng;  Cao, Zheng   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/04/09 chemotherapy  immunotherapy  immunogenic cell death  tumor immune microenvironment   Exploration of the potential association between GLP-1 receptor agonists and suicidal or self-injurious behaviors: a pharmacovigilance study based on the FDA Adverse Event Reporting System database 期刊论文  OAI收割 BMC MEDICINE, 2024, 卷号: 22, 期号: 1, 页码: 13 作者:  Zhou, Jianxing;  Zheng, You;  Xu, Baohua;  Long, Songjun;  Zhu, Li-e   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/03/25 GLP-1RAs  Suicidal or self-injurious behaviors  Pharmacovigilance  FAERS database  Type 2 diabetes  Obesity   Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses 期刊论文  OAI收割 NATURE CHEMICAL BIOLOGY, 2024, 页码: 29 作者:  Zhou, Xiaoyu;  Zhao, Cheng;  Xu, Haiyan;  Xu, Yixiang;  Zhan, Li   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/03/25 New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9 作者:  Zheng, Yingying;  Lu, Li;  Li, Mengyue;  Xu, Dehua;  Zhang, Laishun   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/01/26 Chromone  Thiazolidine-2  4-dione  Protein tyrosine phosphatase 1B  Inhibitors   Discovery, Optimization, and Evaluation of Novel Pyridin-2(1H)-one Analogues as Potent TRK Inhibitors for Cancer Treatment 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1168-1183 作者:  Xu, Zichao;  Peng, Xia;  Zhang, Renjie;  Ji, Yinchun;  You, Mengke   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/02/27 Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRASG12D 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1147-1167 作者:  Zhou, Chuan   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/02/27 Metabolite characterisation of the peptide-drug conjugate LN005 in liver S9s by UHPLC-Orbitrap-HRMS 期刊论文  OAI收割 XENOBIOTICA, 2024, 页码: 9 作者:  Yuan, Yali;  Wang, Weiqiang;  Luo, Jing;  Tang, Chongzhuang;  Zheng, Yuandong   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/02/19 peptide-drug conjugate  PDC  LN005  metabolite identification  liver S9s   Structure-based development of potent and selective type-II kinase inhibitors of RIPK1 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 1, 页码: 319-334 作者:  Qin, Ying;  Li, Dekang;  Qi, Chunting;  Xiang, Huaijiang;  Meng, Huyan   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/03/06 RIPK1  Necroptosis  Type-II kinase inhibitors  Rational design  Lead optimization  Structure-activity relationship  Anti-inflammation  Preclinical drug discovery