中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [12]
采集方式
OAI收割 [12]
内容类型
期刊论文 [12]
发表日期
2019 [12]
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专题:上海药物研究所
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发表日期:2019
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Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070
作者:
Xiao, Li
;
Wang, Yujun
;
Zhang, Mumei
;
Wu, Weiwei
;
Kong, Linghui
  |  
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2020/07/01
Effective Virtual Screening Strategy toward heme-containing proteins: Identification of novel IDO1 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 184, 页码: 23
作者:
Zou, Yi
;
Hu, Yue
;
Ge, Shushan
;
Zheng, Yingbo
;
Li, Yuezhen
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
IDO1
Heme
T cell
Cancer immunotherapy
Virtual screening
Drug design
Molecular dynamics simulation
Spiroalanfurantones A-D, Four Eudesmanolide-Furan Sesquiterpene Adducts with a Pentacyclic 6/6/5/5/5 Skeleton from Inula helenium
期刊论文
OAI收割
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 23, 页码: 9478-9482
作者:
Cai, You-Sheng
;
Wu, Zi
;
Wang, Jian-Rong
;
Zheng, Xiao-Qin
;
Xu, Jie
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 16, 页码: 7473-7488
作者:
Wang, Yulan
;
Dai, Yang
;
Wu, Xiaowei
;
Li, Fei
;
Liu, Bo
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/07/01
Profiling and identification of aqueous extract of Cordyceps sinensis by ultra-high performance liquid chromatography tandem quadrupole-orbitrap mass spectrometry
期刊论文
OAI收割
CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 卷号: 17, 期号: 8, 页码: 631-640
作者:
Yao Chang-Liang
;
Qian Zheng-Ming
;
Tian Wen-Shuai
;
Xu Xiao-Qian
;
Yan Yu
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/07/01
Aqueous extract
Cordyceps sinensis
Dipeptides
Nucleosides
SNX10 (sorting nexin 10) inhibits colorectal cancer initiation and progression by controlling autophagic degradation of SRC
期刊论文
OAI收割
AUTOPHAGY, 2019, 页码: 15
作者:
Zhang, Sulin
;
Yang, Zhiwen
;
Bao, Weilian
;
Liu, Lixin
;
You, Yan
  |  
收藏
  |  
浏览/下载:94/0
  |  
提交时间:2020/07/01
Colorectal cancer
macroautophagy
SNX10
SRC
tumor growth
Design and Synthesis of Potent, Selective Inhibitors of Protein Arginine Methyltransferase 4 against Acute Myeloid Leukemia
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 11, 页码: 5414-5433
作者:
Guo, Zuhao
;
Zhang, Zhuqing
;
Yang, Hong
;
Cao, Danyan
;
Xu, Xiaowei
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2020/07/01
Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:
Wang, Zhen
;
Jiang, Xiangrui
;
Zhang, Xianglei
;
Tian, Guanghui
;
Yang, Rulei
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/07/01
A Thermally Robust La3Si6N11:Ce-in-Glass Film for High-Brightness Blue-Laser-Driven Solid State Lighting
期刊论文
OAI收割
LASER & PHOTONICS REVIEWS, 2019, 卷号: 13, 期号: 2, 页码: 10
作者:
You, Shihai
;
Li, Shuxing
;
Zheng, Peng
;
Zhou, Tianliang
;
Wang, Le
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
color converter
La3Si6N11:Ce
laser lighting and displays
luminescence saturation
phosphor-in-glass film
Targeting PRMT5 Activity Inhibits the Malignancy of Hepatocellular Carcinoma by Promoting the Transcription of HNF4 alpha
期刊论文
OAI收割
THERANOSTICS, 2019, 卷号: 9, 期号: 9, 页码: 2606-2617
作者:
Zheng, Bai-Nan
;
Ding, Chen-Hong
;
Chen, Shi-Jie
;
Zhu, Kongkai
;
Shao, Jingwei
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
PRMT5
HNF4 alpha
hepatocellular carcinoma
cancer stem cells