中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [150]
采集方式
OAI收割 [150]
内容类型
期刊论文 [150]
发表日期
2024 [3]
2023 [15]
2022 [7]
2021 [9]
2020 [7]
2019 [11]
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Pharmacolo... [4]
Chemistry [3]
Life Scien... [2]
Biochemist... [1]
Biophysics [1]
Cell Biolo... [1]
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浏览/检索结果:
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专题:上海药物研究所
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Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses
期刊论文
OAI收割
NATURE CHEMICAL BIOLOGY, 2024, 页码: 29
作者:
Zhou, Xiaoyu
;
Zhao, Cheng
;
Xu, Haiyan
;
Xu, Yixiang
;
Zhan, Li
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/25
Metabolic regulation of homologous recombination repair by MRE11 lactylation
期刊论文
OAI收割
CELL, 2024, 卷号: 187, 期号: 2, 页码: 40
作者:
Chen, Yuping
;
Wu, Jinhuan
;
Zhai, Linhui
;
Zhang, Tingting
;
Yin, Hui
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/04/09
Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRAS
G12D
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1147-1167
作者:
Zhou, Chuan
;
Fan, Zisheng
;
Gu, Yuejiao
;
Ge, Zhiming
;
Tao, Zhaofan
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/27
Epigenetic-based combination therapy and liposomal codelivery overcomes osimertinib-resistant NSCLC via repolarizing tumor-associated macrophages
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:
Lin, Ting-ting
;
Xiong, Wei
;
Chen, Gui-hua
;
He, Yang
;
Long, Li
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/01/26
osimertinib resistance
targeted drug delivery
liposomes
panobinostat
tumor-associated macrophage
combination therapy
Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19
作者:
Wang, Pingyuan
;
Zhu, Wen-Ting
;
Wang, Yajing
;
Song, Shan-Shan
;
Xi, Yong
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2023/10/17
PARP1 inhibitor
Synthetic lethality
Drug resistance
Anticancer
Structure -activity relationship
Hyodeoxycholic acid ameliorates nonalcoholic fatty liver disease by inhibiting RAN-mediated PPARa nucleus-cytoplasm shuttling
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 18
作者:
Zhong, Jing
;
He, Xiaofang
;
Gao, Xinxin
;
Liu, Qiaohong
;
Zhao, Yu
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/12/08
GPCR activation and GRK2 assembly by a biased intracellular agonist
期刊论文
OAI收割
NATURE, 2023, 页码: 27
作者:
Duan, Jia
;
Liu, Heng
;
Zhao, Fenghui
;
Yuan, Qingning
;
Ji, Yujie
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Disruption of ER ion homeostasis maintained by an ER anion channel CLCC1 contributes to ALS-like pathologies
期刊论文
OAI收割
CELL RESEARCH, 2023, 卷号: 33, 期号: 7, 页码: 497-515
作者:
Guo, Liang
;
Mao, Qionglei
;
He, Ji
;
Liu, Xiaoling
;
Piao, Xuejiao
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/03/27
Iodine substitution compromises the aggregation-induced emission (AIE) property and enhances the biothiol sensitivity of quinoline-malononitrile-based fluorescent probes
期刊论文
OAI收割
DYES AND PIGMENTS, 2023, 卷号: 215, 页码: 111246
作者:
Zhu, Guo-Biao
;
Gao, Jie
;
Zhang, Min-Yu
;
He, Liu
;
Han, Hai-Hao
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
Fluorescent probes
Biothiol
Cell imaging
Aggregation-induced emission
Donor-Acceptor
Identification of Histone Lysine Acetoacetylation as a Dynamic Post-Translational Modification Regulated by HBO1
期刊论文
OAI收割
ADVANCED SCIENCE, 2023, 页码: 11
作者:
Gao, Yan
;
Sheng, Xinlei
;
Tan, Doudou
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/10/17
acetoacetate
acetoacetylation
epigenetics
HBO1
histone marks
novel histone modification