机构

• 上海药物研究所 [10]

采集方式

• OAI收割 [10]

内容类型

• 期刊论文 [10]

发表日期

• 2023 [1]
• 2022 [2]
• 2021 [1]
• 2019 [1]
• 2018 [1]
• 2016 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共10条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 A facile and selective derivatization approach on kynurenine-NH2 in daptomycin, leading to the discovery of hexakynomycin to combat multidrug-resistant Gram-positive pathogens especially daptomycin-resistant bacteria 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 14 作者:  Guan, Dongliang;  Li, Jian;  Chen, Feifei;  Li, Jiaqi;  Bian, Xiaolei   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/10/17 Lipopeptide  Daptomycin derivatives  Multidrug-resistant bacteria  Kynurenine  Hexakynomycin   Loss of SIRT5 promotes bile acid-induced immunosuppressive microenvironment and hepatocarcinogenesis 期刊论文  OAI收割 JOURNAL OF HEPATOLOGY, 2022, 卷号: 77, 期号: 2, 页码: 453-466 作者:  Sun, Renqiang;  Zhang, Zhiyong;  Bao, Ruoxuan;  Guo, Xiaozhen;  Gu, Yuan   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/03/21 SIRT5  bile acid  macrophage polarization  immunosuppressive tumor microenvironment  liver cancer   Concise Total Synthesis of Dysoxylactam A and a Simplified Analog 期刊论文  OAI收割 CHINESE JOURNAL OF CHEMISTRY, 2022, 页码: 8 作者:  Yang, Guan-Zhou;  Wang, Lei;  Fan, Yao-Yue;  Lai, Zeng-Wei;  Yu, Xue-Ni   |  收藏  |  浏览/下载：23/0  |  提交时间：2022/08/16 Total synthesis  Dysoxylactam A  Macrocyclolipopeptide  Reversing multidrug resistance  Structure-activity relationship   A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia 期刊论文  OAI收割 Alzheimer's Research & Therapy, 2021, 卷号: 13, 期号: 1 作者:  Xiao,Shifu;  Chan,Piu;  Wang,Tao;  Hong,Zhen;  Wang,Shuzhen   |  收藏  |  浏览/下载：84/0  |  提交时间：2021/05/24 Sodium oligomannate  Efficacy  Safety  Alzheimer’s disease  Clinical trial   Single-base mapping of m6A by an antibody-independent method 期刊论文  OAI收割 SCIENCE ADVANCES, 2019, 卷号: 5, 期号: 7, 页码: eaax0250 作者:  Zhang, Zhang;  Chen, Li-Qian;  Zhao, Yu-Li;  Yang, Cai-Guang;  Roundtree, Ian A.   |  收藏  |  浏览/下载：86/0  |  提交时间：2024/03/21 On-resin peptide ligation via C-terminus benzyl ester 期刊论文  OAI收割 CHINESE CHEMICAL LETTERS, 2018, 卷号: 29, 期号: 7, 页码: 1123-1126 作者:  Zhou, Bin;  Faridoon;  Tian, Xiaobo;  Li, Jian;  Guan, Dongliang   |  收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 On-resin peptide ligation  Peptide benzyl ester  Native chemical ligation  Auxiliary-assisted peptide ligation  Peptide elongation   Synthesis and Anti-HIV-1 Activity Evaluation for Novel 3a,6a-Dihydro-1H-pyrrolo[3,4-c]pyrazole-4,6-dione Derivatives 期刊论文  OAI收割 MOLECULES, 2016, 卷号: 21, 期号: 9 作者:  Liu, Guan-Nan;  Luo, Rong-Hua;  Zhou, Yu;  Zhang, Xing-Jie;  Li, Jian   |  收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08 anti-HIV-1  integrase  synthesis  SAR  AIDS   Synthesis and biological activities of N-indolalkyl piperidine derivatives and their analogues 期刊论文  OAI收割 Chinese Journal of Medicinal Chemistry, 2009, 卷号: 19, 期号: 3, 页码: 161-169 作者:  WANG Guan;  ZHANG Gui-sen;  GUO Lin;  YU Lei-ping;  LI Jian-qi   |  收藏  |  浏览/下载：9/0  |  提交时间：2019/01/08 N-indolalkyl piperidine derivatives  synthesis  5-HT reuptake inhibitors  5-HT_(2A) recepetor  non-opioid analgesic activity   Improved synthesis of raltegravir 期刊论文  OAI收割 Journal of China Pharmaceutical University, 2009, 卷号: 40, 期号: 4, 页码: 297-301 作者:  GUO Di-liang;  LIU Guan-nan;  LI Jian;  ZHOU Yu;  XU Jin-yi   |  收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08 raltegravir  HIV-1 integrase  raltegravir  synthesis  process research   Protective effect of raloxifene on lipopolysaccharide and acid-induced acute lung injury in rats 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2007, 卷号: 28, 期号: 10, 页码: 1585-1590 作者:  Guang-Ju Zhou;  Hong Zhang;  Sheng-De Zhi;  Guo-Ping Jiang;  Jing Wang   |  收藏  |  浏览/下载：10/0  |  提交时间：2019/01/08 acute lung injury  aspiration  fluorodeoxy-glucose  lipopolysaccharide  microPET  pulmonary edema  raloxifene