中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [95]
采集方式
OAI收割 [95]
内容类型
期刊论文 [93]
会议论文 [2]
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2024 [1]
2023 [5]
2022 [5]
2021 [6]
2020 [5]
2019 [9]
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Oncology [1]
Pharmacolo... [1]
Virology [1]
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浏览/检索结果:
共95条,第1-10条
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专题:上海药物研究所
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Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRAS
G12D
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1147-1167
作者:
Zhou, Chuan
;
Fan, Zisheng
;
Gu, Yuejiao
;
Ge, Zhiming
;
Tao, Zhaofan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/02/27
Discovery and Structural Optimization of Covalent ZAP-70 Kinase Inhibitors against Psoriasis
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 15
作者:
Rao, Danni
;
Yang, Tao
;
Feng, Huixu
;
An, Qi
;
Zhang, Shaofeng
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/10/17
Orthogonally Engineered Albumin with Attenuated Macrophage Phagocytosis for the Targeted Visualization and Phototherapy of Liver Cancer
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2023, 卷号: 145, 期号: 31, 页码: 17377-17388
作者:
Dou, Wei-Tao
;
Qiu, Peng
;
Shi, Yuanyuan
;
Zhu, Ling
;
Guo, Chen
  |  
收藏
  |  
浏览/下载:124/0
  |  
提交时间:2023/10/17
Mitochondria-Targeting Small-Molecule NIR-II Fluorescent Probes for Imaging and Treatment of Tumor
期刊论文
OAI收割
ADVANCED THERAPEUTICS, 2023, 页码: 10
作者:
Li, Mingxun
;
Wu, Yibin
;
He, Chunfeng
;
Li, Xinxin
;
Tao, Ji
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
mitochondrial membrane potential
NIR-II imaging
photothermal therapy
small molecule probes
tumors
The PIWI-specific insertion module helps load longer piRNAs for translational activation essential for male fertility
期刊论文
OAI收割
SCIENCE CHINA-LIFE SCIENCES, 2023, 页码: 23
作者:
Wang, Xin
;
Lin, Di-Hang
;
Yan, Yue
;
Wang, An-Hui
;
Liao, Jiaoyang
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
PIWI
piRNAs
PIWI-Ins
translational activation
spermatid development
male fertility
Lactone Stabilized by Crosslinked Cyclodextrin Metal-Organic Frameworks to Improve Local Bioavailability of Topotecan in Lung Cancer
期刊论文
OAI收割
PHARMACEUTICS, 2023, 卷号: 15, 期号: 1, 页码: 14
作者:
Xiong, Ting
;
Guo, Tao
;
He, Yaping
;
Cao, Zeying
;
Xu, Huipeng
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/04/10
topotecan
crosslinked cyclodextrin metal-organic framework
stability
melanoma lung metastasis
local bioavailability
Molecular recognition of two endogenous hormones by the human parathyroid hormone receptor-1
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 11
作者:
Zhao, Li-hua
;
Yuan, Qing-ning
;
Dai, An-tao
;
He, Xin-heng
;
Chen, Chuan-wei
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/04/10
G protein- coupled receptors
parathyroid hormone
PTH-related peptide
PTH receptor-1
cryo-electron microscopy structure
osteoporosis
Deletion of Schizophrenia Susceptibility Gene Ulk4 Leads to Abnormal Cognitive Behaviors via Akt-GSK-3 Signaling Pathway in Mice
期刊论文
OAI收割
SCHIZOPHRENIA BULLETIN, 2022, 页码: 10
作者:
Hu, Ling
;
Zhou, Bing-Yao
;
Yang, Cui-Ping
;
Lu, Da-Yun
;
Tao, Yun-Chao
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/06/15
Unc-51-like kinase 4
schizophrenia
sensorimotor gating
Akt
GSK-3
cerebral cortex
Aristolochic acids exposure was not the main cause of liver tumorigenesis in adulthood
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 5, 页码: 2252-2267
作者:
Chen, Shuzhen
;
Dong, Yaping
;
Qi, Xinming
;
Cao, Qiqi
;
Luo, Tao
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/08/16
Aristolochic acids (AAs)
Mutational signature
AA-DNA adduct
Hepatocellular carcinoma (HCC)
Liver tumorigenesis
Hepatitis B virus (HBV)
Risk factors
Tumor prevention
Fluorescent probes for the detection of disease-associated biomarkers
期刊论文
OAI收割
SCIENCE BULLETIN, 2022, 卷号: 67, 期号: 8, 页码: 853-878
作者:
Dou, Wei-Tao
;
Han, Hai-Hao
;
Sedgwick, Adam C.
;
Zhu, Guo-Biao
;
Zang, Yi
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/08/16
Fluorescent probes
Fluorescence imaging
Biomarker detection
Chemical biology