中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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  • 上海药物研究所 [105]
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Discovery, Optimization, and Evaluation of Novel Pyridin-2(1H)-one Analogues as Potent TRK Inhibitors for Cancer Treatment 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1168-1183
作者:  
Xu, Zichao;  Peng, Xia;  Zhang, Renjie;  Ji, Yinchun;  You, Mengke
  |  收藏  |  浏览/下载:10/0  |  提交时间:2024/02/27
An ultra-compact promoter drives widespread neuronal expression in mouse and monkey brains 期刊论文  OAI收割
CELL REPORTS, 2023, 卷号: 42, 期号: 11, 页码: 21
作者:  
Wang, Jingyi;  Lin, Jianbang;  Chen, Yefei;  Liu, Jing;  Zheng, Qiongping
  |  收藏  |  浏览/下载:34/0  |  提交时间:2024/01/16
GPCR activation and GRK2 assembly by a biased intracellular agonist 期刊论文  OAI收割
NATURE, 2023, 页码: 27
作者:  
Duan, Jia;  Liu, Heng;  Zhao, Fenghui;  Yuan, Qingning;  Ji, Yujie
  |  收藏  |  浏览/下载:12/0  |  提交时间:2023/10/17
A new class of potent liver injury protective compounds: Structural elucidation, total synthesis and bioactivity study 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 8, 页码: 3414-3424
作者:  
Ji, Kailong;  Liu, Wei;  Yin, Weihang;  Kong, Xiangrong;  Xu, Honghong
  |  收藏  |  浏览/下载:8/0  |  提交时间:2023/10/17
Prime editing-based gene correction alleviates the hyperexcitable phenotype and seizures of a genetic epilepsy mouse model 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 4
作者:  
Cao, Bi-rong;  Huang, Yi-ming;  Tian, Fu-yun;  Li, Jin-hui;  Xu, Chun-long
  |  收藏  |  浏览/下载:26/0  |  提交时间:2023/10/17
SYK-mediated epithelial cell state is associated with response to c-Met inhibitors in c-Met-overexpressing lung cancer 期刊论文  OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 13
作者:  
Zhou, Ji;  Zhang, Xu-Chao;  Xue, Shan
  |  收藏  |  浏览/下载:12/0  |  提交时间:2023/10/17
Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2 期刊论文  OAI收割
Signal Transduction and Targeted Therapy, 2023, 卷号: 8, 期号: 5, 页码: 2384-2391
作者:  
Xu, Zhijian;  Shi, Danrong;  Han, Jianbao;  Ling, Yun;  Jiang, Xiangrui
  |  收藏  |  浏览/下载:14/0  |  提交时间:2024/03/27
Structural basis of peptide recognition and activation of endothelin receptors 期刊论文  OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 9
作者:  
Ji, Yujie;  Duan, Jia;  Yuan, Qingning;  He, Xinheng;  Yang, Gong
  |  收藏  |  浏览/下载:10/0  |  提交时间:2023/10/17
Numb/Parkin-directed mitochondrial fitness governs cancer cell fate via metabolic regulation of histone lactylation 期刊论文  OAI收割
CELL REPORTS, 2023, 卷号: 42, 期号: 2, 页码: 112033
作者:  
He, Yuman;  Ji, Zhongzhong;  Gong, Yiming;  Fan, Liancheng;  Xu, Penghui
  |  收藏  |  浏览/下载:1/0  |  提交时间:2024/03/27
Mechanism of hormone and allosteric agonist mediated activation of follicle stimulating hormone receptor 期刊论文  OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 12
作者:  
Duan, Jia;  Xu, Peiyu;  Zhang, Huibing;  Luan, Xiaodong;  Yang, Jiaqi
  |  收藏  |  浏览/下载:11/0  |  提交时间:2023/10/17