中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [54]
采集方式
OAI收割 [54]
内容类型
期刊论文 [53]
专著章节 [1]
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2023 [3]
2022 [3]
2021 [2]
2020 [3]
2019 [5]
2018 [3]
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专题:上海药物研究所
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Effect of an Herbal-Based Injection on 28-Day Mortality in Patients With Sepsis The EXIT-SEP Randomized Clinical Trial
期刊论文
OAI收割
JAMA INTERNAL MEDICINE, 2023, 卷号: 183, 期号: 7, 页码: 647-655
作者:
Liu, Songqiao
;
Yao, Chen
;
Xie, Jianfeng
;
Liu, Hong
;
Wang, Hongliang
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/03/27
Tora3D: an autoregressive torsion angle prediction model for molecular 3D conformation generation
期刊论文
OAI收割
JOURNAL OF CHEMINFORMATICS, 2023, 卷号: 15, 期号: 1, 页码: 14
作者:
Zhang, Zimei
;
Wang, Gang
;
Li, Rui
;
Ni, Lin
;
Zhang, RunZe
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/10/17
Conformations generation
Autoregressive
Transformer
Deep learning
Small molecules
Bioactivity-Driven Synthesis of the Marine Natural Product Naamidine J and Its Derivatives as Potential Tumor Immunological Agents by Inhibiting Programmed Death-Ligand 1
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 8, 页码: 5427-5438
作者:
Fu, Pan-Pan
;
Wang, Qun
;
Zhang, Qing
;
Jin, Yang
;
Liu, Jin
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
Nanosized drug delivery systems modulate the immunosuppressive microenvironment to improve cancer immunotherapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 10
作者:
Yan, Wen-lu
;
Lang, Tian-qun
;
Yuan, Wen-hui
;
Yin, Qi
;
Li, Ya-ping
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/09/30
immunotherapy
nanosized drug delivery systems (NDDSs)
immunosuppressive tumor microenvironment (ITME)
immunogenetic cell death (ICD)
tumor vaccine
Antioxidant Biodegradable Covalent Cyclodextrin Frameworks as Particulate Carriers for Inhalation Therapy against Acute Lung Injury
期刊论文
OAI收割
ACS APPLIED MATERIALS & INTERFACES, 2022, 卷号: 14, 期号: 34, 页码: 38421-38435
作者:
He, Siyu
;
Wu, Li
;
Sun, Hongyu
;
Wu, Di
;
Wang, Caifen
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/09/30
reactive oxygen species-sensitive
covalent cyclodextrin frameworks
acute lung injury
pulmonary drug delivery
ligustrazine
Blood–brain barrier penetration prediction enhanced by uncertainty estimation
期刊论文
OAI收割
Journal of Cheminformatics, 2022, 卷号: 14, 期号: 1
作者:
Tong,Xiaochu
;
Wang,Dingyan
;
Ding,Xiaoyu
;
Tan,Xiaoqin
;
Ren,Qun
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/08/16
Blood–brain barrier penetration
BBBp prediction
Uncertainty estimation
Four new diterpenoids from the twigs and leaves of Phyllanthus acidus
期刊论文
OAI收割
TETRAHEDRON, 2021, 卷号: 91, 页码: 6
作者:
Yuan, Yu-Rong
;
Li, Yan-Wen
;
Huang, Yi-Qi
;
Liu, Qun-fang
;
Ren, Yu-Hao
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/08/17
Phyllanthus acidus
Cleistanthane-type diterpenoid
ECD calculation
Biosynthetic pathway
Cytotoxicity
A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia
期刊论文
OAI收割
Alzheimer's Research & Therapy, 2021, 卷号: 13, 期号: 1
作者:
Xiao,Shifu
;
Chan,Piu
;
Wang,Tao
;
Hong,Zhen
;
Wang,Shuzhen
  |  
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2021/05/24
Sodium oligomannate
Efficacy
Safety
Alzheimer’s disease
Clinical trial
Comparative Transcriptomic and Proteomic Analyses Prove that IFN-lambda 1 is a More Potent Inducer of ISGs than IFN-alpha against Porcine Epidemic Diarrhea Virus in Porcine Intestinal Epithelial Cells
期刊论文
OAI收割
JOURNAL OF PROTEOME RESEARCH, 2020, 卷号: 19, 期号: 9, 页码: 3697-3707
作者:
Zhao, Mingzhi
;
Li, Liang
;
Zhai, Linhui
;
Yue, Qi
;
Liu, Hongyu
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2020/12/21
intestinal epithelial cell
IFN-lambda 1
IFN-alpha
anti-PEDV
transcriptomics
proteomics
BRD4 inhibitor nitroxoline enhances the sensitivity of multiple myeloma cells to bortezomib in vitro and in vivo by promoting mitochondrial pathway-mediated cell apoptosis
期刊论文
OAI收割
THERAPEUTIC ADVANCES IN HEMATOLOGY, 2020, 卷号: 11, 页码: 12
作者:
Li, Guang
;
Zheng, Yan-Hua
;
Xu, Li
;
Feng, Juan
;
Tang, Hai-Long
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/12/24
apoptosis
BRD4 inhibitor
G1 phase cell cycle checkpoint
multiple myeloma