机构

• 上海药物研究所 [48]

采集方式

• OAI收割 [48]

内容类型

• 期刊论文 [47]
• 会议论文 [1]

发表日期

• 2024 [1]
• 2023 [5]
• 2022 [4]
• 2021 [3]
• 2020 [3]
• 2019 [9]
• 更多

学科主题

筛选

浏览/检索结果: 共48条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery and Optimization of WDR5 Inhibitors via Cascade Deoxyribonucleic Acid-Encoded Library Selection Approach 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1079-1092 作者:  Qin, Shaozhao;  Feng, Lijian;  Zhao, Qingyi;  Yan, Ziqin;  Lyu, Xilin   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/02/27 Combination of irinotecan silicasome nanoparticles with radiation therapy sensitizes immunotherapy by modulating the activation of the cGAS/STING pathway for colorectal cancer 期刊论文  OAI收割 MATERIALS TODAY BIO, 2023, 卷号: 23, 页码: 16 作者:  Wang, Lu;  Zhang, Tianyu;  Zheng, Yile;  Li, Yuting;  Tang, Xiyuan   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/11 ABPP-CoDEL: Activity-Based Proteome Profiling-Guided Discovery of Tyrosine-Targeting Covalent Inhibitors from DNA-Encoded Libraries 期刊论文  OAI收割 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2023, 卷号: 145, 期号: 46, 页码: 25283-25292 作者:  Jiang, Lulu;  Liu, Sixiu;  Jia, Xinglong;  Gong, Qinting;  Wen, Xin   |  收藏  |  浏览/下载：24/0  |  提交时间：2024/01/16 Discovery, SAR Study of GST Inhibitors from a Novel Quinazolin-4(1H)-one Focused DNA-Encoded Library 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 15 作者:  Wen, Xin;  Zhang, Minmin;  Duan, Zhiqiang;  Suo, Yanrui;  Lu, Weiwei   |  收藏  |  浏览/下载：30/0  |  提交时间：2023/10/17 Structure-based discovery of potent USP28 inhibitors derived from Vismodegib 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 15 作者:  Zhou, Di;  Xu, Zhuo;  Huang, Yaodong;  Wang, Hui;  Zhu, Xiaoli   |  收藏  |  浏览/下载：22/0  |  提交时间：2023/10/17 USP28  Structure-based  Vismodegib derivatives  Structure-activity relationships  c-Myc   Fructose-1,6-bisphosphatase 1 dephosphorylates I kappa B alpha and suppresses colorectal tumorigenesis 期刊论文  OAI收割 CELL RESEARCH, 2023, 页码: 13 作者:  Zhu, Wencheng;  Chu, Huiying;  Zhang, Yajuan;  Luo, Tianhang;  Yu, Hua   |  收藏  |  浏览/下载：22/0  |  提交时间：2023/04/10 Hepatic cytochrome P450 8B1 and cholic acid potentiate intestinal epithelial injury in colitis by suppressing intestinal stem cell renewal 期刊论文  OAI收割 CELL STEM CELL, 2022, 卷号: 29, 期号: 9, 页码: 1366-+ 作者:  Chen, Li;  Jiao, Tingying;  Liu, Weiwei;  Luo, Yuhong;  Wang, Jue   |  收藏  |  浏览/下载：20/0  |  提交时间：2023/04/10 Triazine-Based Covalent DNA-Encoded Libraries for Discovery of Covalent Inhibitors of Target Proteins 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2022, 页码: 8 作者:  Li, Linjie;  Su, Mingbo;  Lu, Weiwei;  Song, Hongzhi;  Liu, Jiaxiang   |  收藏  |  浏览/下载：20/0  |  提交时间：2022/09/30 DNA encoded library  covalent library  library design  covalent inhibitors   Systematic Qualitative and Quantitative Analyses of Wenxin Granule via Ultra-High Performance Liquid Chromatography Coupled with Ion Mobility Quadrupole Time-of-Flight Mass Spectrometry and Triple Quadrupole-Linear Ion Trap Mass Spectrometry 期刊论文  OAI收割 MOLECULES, 2022, 卷号: 27, 期号: 11, 页码: 21 作者:  Mi, Yueguang;  Hu, Wandi;  Li, Weiwei;  Wan, Shiyu;  Xu, Xiaoyan   |  收藏  |  浏览/下载：28/0  |  提交时间：2022/08/16 Wenxin granule  multicomponent characterization  HDMSE-HDDDA  UHPLC-sMRM  quality evaluation   The upregulated intestinal folate transporters direct the uptake of ligand-modified nanoparticles for enhanced oral insulin delivery 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 3, 页码: 1460-1472 作者:  Li, Jingyi;  Zhang, Yaqi;  Yu, Miaorong;  Wang, Aohua;  Qiu, Yu   |  收藏  |  浏览/下载：35/0  |  提交时间：2022/06/15 Ligand-modified nanoparticles  Transporter  Proton-coupled folate transporter  Expression level  Endocytosis  Intracellular trafficking  Diabetes  Oral insulin delivery