机构

• 上海药物研究所 [116]

采集方式

• OAI收割 [116]

内容类型

• 期刊论文 [110]
• 会议论文 [6]

发表日期

• 2024 [2]
• 2023 [4]
• 2022 [10]
• 2021 [7]
• 2020 [11]
• 2019 [6]
• 更多

学科主题

• Biochemist... [3]
• Pharmacolo... [3]
• Chemistry [1]
• Endocrinol... [1]
• Life Scien... [1]

筛选

浏览/检索结果: 共116条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Proteomics analysis of histone deacetylase inhibitor-resistant solid tumors reveals resistant signatures and potential drug combinations 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2024, 页码: 11 作者:  Hao, Bing-bing;  Ma, Ke;  Xu, Jun-yu;  Fan, Ru-feng;  Zhao, Wen-si   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/03/25 solid tumor  histone deacetylase inhibitor  vorinostat (SAHA)  drug resistance  proteomics   Discovery and optimization of thieno[3,2-d]pyrimidine derivatives as highly selective inhibitors of cyclin-dependent kinase 7 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 263, 页码: 21 作者:  Zhang, Hongjin;  Lin, Guohao;  Jia, Suyun;  Zhang, Ying;  Wu, Jianbo   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/01/26 Thieno[3  d ]pyrimidine derivative  Cyclin-dependent kinase 7  Small molecule inhibitor  Kinome selectivity  Triple negative breast cancer   Tail engagement of arrestin at the glucagon receptor 期刊论文  OAI收割 NATURE, 2023, 页码: 21 作者:  Chen, Kun;  Zhang, Chenhui;  Lin, Shuling;  Yan, Xinyu;  Cai, Heng   |  收藏  |  浏览/下载：15/0  |  提交时间：2023/10/17 Preclinical Evaluation of 9MW2821, a Site-Specific Monomethyl Auristatin E-based Antibody-Drug Conjugate for Treatment of Nectin-4-expressing Cancers 期刊论文  OAI收割 MOLECULAR CANCER THERAPEUTICS, 2023, 卷号: 22, 期号: 8, 页码: 913-925 作者:  Zhou, Wei;  Fang, Peng   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 Effect of an Herbal-Based Injection on 28-Day Mortality in Patients With Sepsis The EXIT-SEP Randomized Clinical Trial 期刊论文  OAI收割 JAMA INTERNAL MEDICINE, 2023, 卷号: 183, 期号: 7, 页码: 647-655 作者:  Liu, Songqiao;  Yao, Chen;  Xie, Jianfeng;  Liu, Hong;  Wang, Hongliang   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/03/27 Improved 2α-Hydroxylation Efficiency of Steroids by CYP154C2 Using Structure-Guided Rational Design 期刊论文  OAI收割 APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2023, 卷号: 89, 期号: 3 作者:  Gao, Qilin;  Ma, Bingbing;  Wang, Qianwen;  Zhang, Hao;  Fushinobu, Shinya   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/03/27 P450  testosterone  androstenedione  crystal structure  rational design   Molecular Mechanisms of Mercury-Sensitive Aquaporins 期刊论文  OAI收割 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2022, 页码: 13 作者:  Xie, Huayong;  Ma, Shaojie;  Zhao, Yongxiang;  Zhou, Hu;  Tong, Qiong   |  收藏  |  浏览/下载：17/0  |  提交时间：2023/04/10 Nrf2-mediated liver protection by 18 beta-glycyrrhetinic acid against pyrrolizidine alkaloid-induced toxicity through PI3K/Akt/GSK3 beta pathway 期刊论文  OAI收割 PHYTOMEDICINE, 2022, 卷号: 102, 页码: 12 作者:  Wang, Zhangting;  Ma, Jiang;  He, Yisheng;  Miu, Kai-Kei   |  收藏  |  浏览/下载：47/0  |  提交时间：2022/08/30 Pyrrolizidine alkaloids  Herb-induced liver injury  18 beta-glycyrrhetinic acid  Liquorice  Nuclear factor erythroid-2-related factor 2  PI3K/Akt/GSK3 beta   Multimodule characterization of immune subgroups in intrahepatic cholangiocarcinoma reveals distinct therapeutic vulnerabilities 期刊论文  OAI收割 JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 卷号: 10, 期号: 7, 页码: 14 作者:  Lin, Jian;  Dai, Yuting;  Sang, Chen;  Song, Guohe;  Xiang, Bin   |  收藏  |  浏览/下载：35/0  |  提交时间：2022/08/30 tumor microenvironment  cytotoxicity  immunologic  drug therapy  combination   Discovery of CECR2 Bromodomain Inhibitors with High Selectivities over BPTF Bromodomain 期刊论文  OAI收割 CHINESE JOURNAL OF CHEMISTRY, 2022, 页码: 2072-2080 作者:  Lu, Haibo;  Zu, Shijia;  Duan, Zhe;  Feng, Yueyao;  Wang, Jie   |  收藏  |  浏览/下载：24/0  |  提交时间：2022/08/16 CECR2 bromodomain  BPTF bromodomain  Inhibitors  Structure-activity relationships  chemical probe