机构

• 上海药物研究所 [65]

采集方式

• OAI收割 [65]

内容类型

• 期刊论文 [65]

发表日期

• 2024 [1]
• 2023 [5]
• 2022 [1]
• 2021 [3]
• 2020 [4]
• 2019 [6]
• 更多

学科主题

筛选

浏览/检索结果: 共65条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 DRAK2 suppresses autophagy by phosphorylating ULK1 at Ser56 to diminish pancreatic β cell function upon overnutrition 期刊论文  OAI收割 SCIENCE TRANSLATIONAL MEDICINE, 2024, 卷号: 16, 期号: 733, 页码: 16 作者:  Lu, Yuting;  Xu, Junyu;  Li, Yufeng;  Wang, Ruoran;  Dai, Chengqiu   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/03/13 Anxiolytic effect of antidiabetic metformin is mediated by AMPK activation in mPFC inhibitory neurons 期刊论文  OAI收割 MOLECULAR PSYCHIATRY, 2023, 页码: 11 作者:  Zhang, Yong-mei;  Zong, Hai-chao;  Qi, Ying-bei;  Chang, Liu-liu;  Gao, Ya-nan   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/12/08 Preclinical Evaluation of 9MW2821, a Site-Specific Monomethyl Auristatin E-based Antibody-Drug Conjugate for Treatment of Nectin-4-expressing Cancers 期刊论文  OAI收割 MOLECULAR CANCER THERAPEUTICS, 2023, 卷号: 22, 期号: 8, 页码: 913-925 作者:  Zhou, Wei;  Fang, Peng;  Yu, Dongan;  Ren, Hongyuan;  You, Meng   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 The PIWI-specific insertion module helps load longer piRNAs for translational activation essential for male fertility 期刊论文  OAI收割 SCIENCE CHINA-LIFE SCIENCES, 2023, 页码: 23 作者:  Wang, Xin;  Lin, Di-Hang;  Yan, Yue;  Wang, An-Hui;  Liao, Jiaoyang   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/10/17 PIWI  piRNAs  PIWI-Ins  translational activation  spermatid development  male fertility   Shape and Shear Stress Impact on the Toxicity of Mesoporous Silica Nanoparticles: In Vitro and In Vivo Evidence 期刊论文  OAI收割 MOLECULAR PHARMACEUTICS, 2023, 卷号: 20, 期号: 6, 页码: 3187-3201 作者:  Cheng, Yaxin;  Tao, Jinsong;  Zhang, Yaqi;  Xi, Long;  Han, Run   |  收藏  |  浏览/下载：25/0  |  提交时间：2023/10/17 mesoporous silica nanoparticles (MSNs)  toxicity  shape  shear stress  in vitro blood flow model   AXL antibody and AXL-ADC mediate antitumor efficacy via targeting AXL in tumor-intrinsic epithelial-mesenchymal transition and tumor-associated M2-like macrophage 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 14 作者:  Pei, Jin-peng;  Wang, Yue;  Ma, Lan-ping;  Wang, Xin;  Liu, Liang   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/04/10 AXL  NSCLC  TNBC  M2-macrophage  antibody-drug conjugate   Development of a novel lactate dehydrogenase A inhibitor with potent antitumor activity and immune activation 期刊论文  OAI收割 CANCER SCIENCE, 2022, 卷号: 113, 期号: 9, 页码: 2974-2985 作者:  Du, Mengyan;  Yu, Ting;  Zhan, Qinjinge;  Li, Han;  Zou, Yiping   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/03/21 immunity  lactate  LDHA inhibitor  metabolic reprogramming  tumor microenvironment   Requirments for primary human hepatocyte 期刊论文  OAI收割 CELL PROLIFERATION, 2021, 页码: 6 作者:  Peng, Zhaoliang;  Wu, Jiaying;  Hu, Shijun;  Ma, Aijin;  Wang, Lei   |  收藏  |  浏览/下载：29/0  |  提交时间：2022/06/15 primary human hepatocyte  quality control  standard   Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Jiang, Kai-long;  Tong, Le-xian;  Wang, Tao;  Wang, Han-lin;  Hu, Xiao-bei   |  收藏  |  浏览/下载：48/0  |  提交时间：2021/05/24 CHK1 inhibitors  PY34  drug sensitivity  c-Myc  hematologic malignancies   Discovery of MTR-106 as a highly potent G-quadruplex stabilizer for treating BRCA-deficient cancers 期刊论文  OAI收割 INVESTIGATIONAL NEW DRUGS, 2021, 页码: 9 作者:  Li, Meng-Zhu;  Meng, Tao;  Song, Shan-Shan;  Bao, Xu-Bin;  Ma, Lan-Ping   |  收藏  |  浏览/下载：24/0  |  提交时间：2021/05/24 G-quadruplex stabilizer  MTR-106  BRCA-deficiency  PARP inhibitor  DNA damage