机构

• 上海药物研究所 [17]

采集方式

• OAI收割 [17]

内容类型

• 期刊论文 [17]

发表日期

• 2022 [1]
• 2021 [2]
• 2019 [1]
• 2018 [1]
• 2014 [1]
• 2010 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共17条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 SOMCL-19-133, a novel, selective, and orally available inhibitor of NEDD8-activating enzyme (NAE) for cancer therapy 期刊论文  OAI收割 NEOPLASIA, 2022, 卷号: 32, 页码: 12 作者:  Zhou, Li-Na;  Xiong, Chaodong;  Cheng, Yong-Jun;  Song, Shan-Shan;  Bao, Xu-Bin   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/04/10 SOMCL-19-133  NAE inhibitor  MLN4924  NEDD8  Oral administration   Discovery of MTR-106 as a highly potent G-quadruplex stabilizer for treating BRCA-deficient cancers 期刊论文  OAI收割 INVESTIGATIONAL NEW DRUGS, 2021, 页码: 9 作者:  Li, Meng-Zhu;  Meng, Tao;  Song, Shan-Shan;  Bao, Xu-Bin;  Ma, Lan-Ping   |  收藏  |  浏览/下载：24/0  |  提交时间：2021/05/24 G-quadruplex stabilizer  MTR-106  BRCA-deficiency  PARP inhibitor  DNA damage   Novel bivalent BET inhibitor N2817 exhibits potent anticancer activity and inhibits TAF1 期刊论文  OAI收割 BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 185, 页码: 14 作者:  Wu, Qian;  Chen, Dan-Qi;  Sun, Lin;  Huan, Xia-Juan;  Bao, Xu-Bin   |  收藏  |  浏览/下载：39/0  |  提交时间：2021/05/24 N2817  Bivalent BET inhibitors  Monovalent BET inhibitors  TAF1  Anticancer activity   Sustained ER stress promotes hyperglycemia by increasing glucagon action through the deubiquitinating enzyme USP14 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 卷号: 116, 期号: 43, 页码: 21732-21738 作者:  Liu, Bin;  Zhang, Zhijian;  Hu, Yanyun;  Lu, Yan;  Li, Duanzhuo   |  收藏  |  浏览/下载：27/0  |  提交时间：2020/07/01 type 2 diabetes  gluconeogenesis  hepatic glucose production  ER stress  USP14   Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2018, 卷号: 9 作者:  Liu, Bin;  Jiang, Shangwen;  Li, Min;  Xiong, Xuelian;  Zhu, Mingrui   |  收藏  |  浏览/下载：109/0  |  提交时间：2019/01/08 Bioactive Acylphloroglucinols with Adamantyl Skeleton from Hypericum Sampsonii 期刊论文  OAI收割 ORGANIC LETTERS, 2014, 卷号: 16, 期号: 24, 页码: 6322-6325 作者:  Zhu, Hucheng;  Chen, Chunmei;  Yang, Jing;  Li, Xiao-Nian;  Liu, Junjun   |  收藏  |  浏览/下载：19/0  |  提交时间：2019/01/08 Identification of the UDP-glucuronosyltransferase isozyme involved in senecionine glucuronidation in human liver microsomes 期刊论文  OAI收割 Drug metabolism and disposition: the biological fate of chemicals, 2010, 卷号: 38, 期号: 4, 页码: 626-34 作者:  He, Yu-Qi;  Liu, Yong;  Zhang, Bin-Feng;  Liu, Hui-Xin;  Lu, Yan-Liu   |  收藏  |  浏览/下载：8/0  |  提交时间：2019/01/08 Design, synthesis and biological evaluation of novel dual inhibitors of acetylcholinesterase and beta-secretase 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2009, 卷号: 17, 期号: 4, 页码: 1600-1613 作者:  Zhu, Yiping;  Xiao, Kun;  Ma, Lanping;  Xiong, Bin;  Fu, Yan   |  收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08 AD  AChE  BACE-1  Dual inhibitor  HE  HMC  HEA   Identification of Major Alkaloids in Rat Urine by HPLC/DAD/ESI-MS/MS Method Following Oral Administration of Cortex Phellodendri Decoction 期刊论文  OAI收割 HELVETICA CHIMICA ACTA, 2009, 卷号: 92, 期号: 2, 页码: 379-398 作者:  Ma, Chun-Hui;  Li, Zhi-Xiong;  Wang, Long-Xing;  Tang, Yi-Hong;  Xiao, Hong-Bin   |  收藏  |  浏览/下载：8/0  |  提交时间：2019/01/08 Eight New Diterpenoids from the Roots of Euphorbia nematoopha 期刊论文  OAI收割 HELVETICA CHIMICA ACTA, 2008, 卷号: 91, 期号: 11, 页码: 2139-2147 作者:  He, Fei;  Pu, Jian-Xin;  Huang, Sheng-Xiong;  Xiao, Wei-Lie;  Yang, Li-Bin   |  收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08