中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [14]
采集方式
OAI收割 [14]
内容类型
期刊论文 [14]
发表日期
2023 [1]
2022 [1]
2021 [3]
2020 [2]
2018 [2]
2016 [1]
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专题:上海药物研究所
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Integrative multi-omics and drug-response characterization of patient-derived prostate cancer primary cells
期刊论文
OAI收割
Signal Transduction and Targeted Therapy, 2023, 卷号: 8, 期号: 6, 页码: 3013-3028
作者:
Wang, Ziruoyu
;
Li, Yanan
;
Zhao, Wensi
;
Jiang, Shuai
;
Huang, Yuqi
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/03/27
Rutaecarpine Promotes Adipose Thermogenesis and Protects against HFD-Induced Obesity via AMPK/PGC-1 alpha Pathway
期刊论文
OAI收割
PHARMACEUTICALS, 2022, 卷号: 15, 期号: 4, 页码: 18
作者:
Chen, Dandan
;
Duan, Yanan
;
Yu, Shuxiang
;
Zhang, Xinwen
;
Li, Ni
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/06/15
obesity
rutaecarpine
adipocytes
thermogenesis
peroxisome-proliferator-activated receptor gamma co-activator-1 alpha
AMP-activated protein kinase
browning
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
OAI收割
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
  |  
收藏
  |  
浏览/下载:87/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance (vol 19, 90, 2020)
期刊论文
OAI收割
MOLECULAR CANCER, 2021, 卷号: 20, 期号: 1, 页码: 1
作者:
Zhang, Tao
;
Qu, Rong
;
Chan, Shingpan
;
Lai, Mengzhen
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:87/0
  |  
提交时间:2021/11/04
Correction to: Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance
期刊论文
OAI收割
Molecular Cancer, 2021, 卷号: 20, 期号: 1
作者:
Zhang,Tao
;
Qu,Rong
;
Chan,Shingpan
;
Lai,Mengzhen
;
Tong,Linjiang
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2021/11/04
Simultaneous determination of sutetinib and its active metabolite sutetinibN-oxide in human plasma by liquid chromatography-tandem mass spectrometry: Evaluation of plasma stability
期刊论文
OAI收割
BIOMEDICAL CHROMATOGRAPHY, 2020, 页码: 9
作者:
Qiu, Yanan
;
Tang, Chongzhuang
;
Li, Ranran
;
Cao, Sumin
;
Zhang, Yuqiang
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/12/24
LC-MS
MS
N-oxide
stability
sutetinib
Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance
期刊论文
OAI收割
MOLECULAR CANCER, 2020, 卷号: 19, 期号: 1, 页码: 15
作者:
Zhang, Tao
;
Qu, Rong
;
Chan, Shingpan
;
Lai, Mengzhen
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2020/07/01
Non-small cell lung cancer (NSCLC)
EGFR T790M
Small-molecule inhibitor
Drug resistance
Ack1
Design, synthesis, and structure-activity relationships of novel 4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinoline and 5,8,12,12a-tetrahydro-6H-thieno[2 ',3 ': 4,5]pyrido[2,1-a]isoquinoline derivatives as cellular activators of adenosine 5 '-monophosphate-activated protein kinase (AMPK)
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 8, 页码: 2017-2027
作者:
Gu, Zhanni
;
Wu, Lingyan
;
Duan, Yanan
;
Wang, Jiang
;
Zhou, Shengbin
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/01/08
Adenosine 5 '-monophosphate-activated protein kinase
AMPK activators
Berberine
Tetrahydroberberine
T2DM
identificationofcompoundd2923asanovelantitumoragenttargetingcsf1r
期刊论文
OAI收割
actapharmacologicasinica, 2018, 卷号: 039, 期号: 011, 页码: 1768
作者:
Liu Yingqiang
;
Wang Yanan
;
Lu Xiaoyun
;
Tong Linjiang
;
Li Yan
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
肿瘤组织
代理人
apoptosis
生长抑制率
复合
指向
鉴定
巨噬细胞
Design, Synthesis, and Biological Evaluation of Indoline and Indole Derivatives as Potent and Selective alpha(1A)-Adrenoceptor Antagonists
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 8, 页码: 3826-3839
作者:
Zhao, Fei
;
Li, Jing
;
Chen, Ying
;
Tian, Yanxin
;
Wu, Chenglin
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/01/08