中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [353]
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OAI收割 [353]
内容类型
期刊论文 [346]
会议论文 [7]
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2024 [5]
2023 [31]
2022 [19]
2021 [28]
2020 [27]
2019 [24]
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Chemistry [6]
Pharmacolo... [5]
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浏览/检索结果:
共353条,第1-10条
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专题:上海药物研究所
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Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses
期刊论文
OAI收割
NATURE CHEMICAL BIOLOGY, 2024, 页码: 29
作者:
Zhou, Xiaoyu
;
Zhao, Cheng
;
Xu, Haiyan
;
Xu, Yixiang
;
Zhan, Li
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/03/25
An LQT2-related mutation in the voltage-sensing domain is involved in switching the gating polarity of hERG
期刊论文
OAI收割
BMC BIOLOGY, 2024, 卷号: 22, 期号: 1, 页码: 14
作者:
Liu, Zhipei
;
Wang, Feng
;
Yuan, Hui
;
Tian, Fuyun
;
Yang, Chuanyan
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/03/13
hERG
K525N
Gating Polarity
Voltage-Sensing Domain
LQT2
MATLAB language assisted data acquisition and processing in liquid chromatography Orbitrap mass spectrometry: Application to the identification and differentiation of Radix Bupleuri from its adulterants
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY A, 2024, 卷号: 1714, 页码: 10
作者:
Shen, Xuan-jing
;
Zhang, Jian-qing
;
An, Ya-ling
;
Yang, Lin
;
Li, Xiao-lan
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/02/27
Radix Bupleuri
Adulterants
MATLAB
precursor ion list (PIL)
identification
The promise and challenges of combination therapies with antibody-drug conjugates in solid tumors
期刊论文
OAI收割
JOURNAL OF HEMATOLOGY & ONCOLOGY, 2024, 卷号: 17, 期号: 1, 页码: 32
作者:
Wei, Qing
;
Li, Peijing
;
Yang, Teng
;
Zhu, Jiayu
;
Sun, Lu
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2024/02/27
Antibody-drug conjugate
Solid tumor
Combination therapy
Immunotherapy
Targeted therapy
A novel phthalazinone derivative as a capsid assembly modulator inhibits hepatitis B virus expression
期刊论文
OAI收割
ANTIVIRAL RESEARCH, 2024, 卷号: 221, 页码: 14
作者:
Yang, Li
;
Gong, Ying
;
Liu, Feifei
;
Chen, Wuhong
;
Wang, Xinran
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/02/19
Hepatitis B virus
Capsid assembly
Phthalazinone derivatives
Apoptosis
Ascorbic Acid Reprograms Epigenome and Epitranscriptome by Reducing Fe(III) in the Catalytic Cycle of Dioxygenases
期刊论文
OAI收割
ACS CHEMICAL BIOLOGY, 2023, 卷号: 19, 期号: 1, 页码: 129-140
作者:
He, Weizhi
;
Yin, Xiaotong
;
Xu, Chu
;
Liu, Xiangyue
;
Huang, Yue
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/02/27
Systematical targeted multicomponent characterization and comparison of Arnebiae Radix and its three confusing species by offline two-dimensional liquid chromatography/LTQ-Orbitrap mass spectrometry
期刊论文
OAI收割
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2023, 页码: 13
作者:
Sha, Fei
;
Zhang, Jianqing
;
Yang, Huanya
;
Hu, Yunshu
;
Wei, Wenlong
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/02/19
Arnebiae Radix
Two-dimensional liquid chromatography
Mass defect filter
Precursor ion list
Components characterization
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects
Dihydrocelastrol induces antitumor activity and enhances the sensitivity of bortezomib in resistant multiple myeloma by inhibiting STAT3-dependent PSMB5 regulation
期刊论文
OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2023, 卷号: 55, 期号: 12, 页码: 1884-1891
作者:
Jin, Shuhan
;
Li, Bo
;
Zhang, Bibo
;
Gao, Xuejie
;
Jia, Xinyan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/02/27
dihydrocelastrol
multiple myeloma
JAK2/STAT3
PSMB5
bortezomib resistance
Discovery of PVD-06 as a Subtype-Selective and Efficient PTPN2 Degrader
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 22, 页码: 15269-15287
作者:
Hu, Linghao
;
Li, Huiyun
;
Qin, Junlin
;
Yang, Dan
;
Liu, Jieming
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/02/27