机构

• 上海药物研究所 [28]

采集方式

• OAI收割 [28]

内容类型

• 期刊论文 [27]
• 会议论文 [1]

发表日期

• 2024 [1]
• 2023 [4]
• 2022 [3]
• 2021 [2]
• 2020 [1]
• 2019 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共28条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses 期刊论文  OAI收割 NATURE CHEMICAL BIOLOGY, 2024, 页码: 29 作者:  Zhou, Xiaoyu;  Zhao, Cheng;  Xu, Haiyan;  Xu, Yixiang;  Zhan, Li   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/03/25 Discovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR plus Human Prostate Cancer 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 18, 页码: 13280-13303 作者:  Xiang, Weiguo;  Zhao, Lijie;  Han, Xin;  Xu, Tianfeng;  Kregel, Steven   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/08 Effect of an Herbal-Based Injection on 28-Day Mortality in Patients With Sepsis The EXIT-SEP Randomized Clinical Trial 期刊论文  OAI收割 JAMA INTERNAL MEDICINE, 2023, 卷号: 183, 期号: 7, 页码: 647-655 作者:  Liu, Songqiao;  Yao, Chen;  Xie, Jianfeng;  Liu, Hong;  Wang, Hongliang   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/03/27 Preparation and characterization of nanobodies targeting SARS-CoV-2 papain-like protease 期刊论文  OAI收割 PROTEIN EXPRESSION AND PURIFICATION, 2023, 卷号: 207, 页码: 106267 作者:  Qiao, Huarui;  Li, Lingyun;  Wang, Lu;  Yu, Haijun;  Hu, Fangzheng   |  收藏  |  浏览/下载：0/0  |  提交时间：2024/03/27 SARS-CoV-2  Papain like protease (PLpro)  Nanobody  PLpro inhibitor   Selective degradation of cellular BRD3 and BRD4-L promoted by PROTAC molecules in six cancer cell lines 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 17 作者:  Yan, Ziqin;  Lyu, Xilin;  Lin, Dongze;  Wu, Gaoxing;  Gong, Yang   |  收藏  |  浏览/下载：25/0  |  提交时间：2023/10/17 Quaternized Acridine Maleimide MALDI Probe Enables Mass Spectrometry Imaging of Thiols 期刊论文  OAI收割 ANALYTICAL CHEMISTRY, 2022, 页码: 8 作者:  Ma, Zhenghua;  Yuan, Jie;  Xu, Jianfeng;  Li, Lizhi;  Tang, Chunping   |  收藏  |  浏览/下载：25/0  |  提交时间：2022/12/13 Discovery of a selective and covalent small-molecule inhibitor of BFL-1 protein that induces robust apoptosis in cancer cells 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 236, 页码: 114327 作者:  Feng, Xuexin;  Yan, Ziqin;  Zhou, Feilong;  Lou, Jianfeng;  Lyu, Xilin   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/03/21 BFL-1  Apoptosis  Covalent inhibitor  Cytochrome c  BCL-2  Protein-Protein interaction   Structure-Based Discovery of MDM2/4 Dual Inhibitors that Exert Antitumor Activities against MDM4-Overexpressing Cancer Cells 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 8, 页码: 6207-6230 作者:  Zhang, Shiyan;  Yan, Ziqin;  Li, Yafang;  Gong, Yang;  Lyu, Xilin   |  收藏  |  浏览/下载：21/0  |  提交时间：2022/08/16 Structures of G(i)-bound metabotropic glutamate receptors mGlu2 and mGlu4 期刊论文  OAI收割 NATURE, 2021, 卷号: 594, 期号: 7864, 页码: 583-+ 作者:  Lin, Shuling;  Han, Shuo;  Cai, Xiaoqing;  Tan, Qiuxiang;  Zhou, Kexiu   |  收藏  |  浏览/下载：35/0  |  提交时间：2021/11/24 Structures of Gi-bound metabotropic glutamate receptors mGlu2 and mGlu4 期刊论文  OAI收割 NATURE, 2021, 页码: 23 作者:  Lin, Shuling;  Han, Shuo;  Cai, Xiaoqing;  Tan, Qiuxiang;  Zhou, Kexiu   |  收藏  |  浏览/下载：23/0  |  提交时间：2021/08/17