中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [130]
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OAI收割 [130]
内容类型
期刊论文 [130]
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2023 [6]
2022 [6]
2021 [13]
2020 [13]
2019 [3]
2018 [9]
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浏览/检索结果:
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专题:上海药物研究所
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A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects
Liang-Ge-San inhibits dengue virus serotype 2 infection by reducing caveolin1-induced cytoplasmic heat shock protein 70 translocation into the plasma membrane
期刊论文
OAI收割
PHYTOMEDICINE, 2023, 卷号: 119, 页码: 14
作者:
Chen, Xi
;
Yang, Jia-bin
;
Cao, Hui-hui
;
Fang, Xiao-chuan
;
Liu, Shan-hong
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/10/17
Liang-Ge-San
Dengue virus serotype 2
Heat shock protein 70
Caveolin1
Envelope protein
Antiandrogen treatment induces stromal cell reprogramming to promote castration resistance in cancer
期刊论文
OAI收割
CANCER CELL, 2023, 卷号: 41, 期号: 7, 页码: 1345-+
作者:
Wang, Hanling
;
Li, Ni
;
Liu, Qiuli
;
Guo, Jiacheng
;
Pan, Qiang
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/10/17
Prime editing-based gene correction alleviates the hyperexcitable phenotype and seizures of a genetic epilepsy mouse model
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 4
作者:
Cao, Bi-rong
;
Huang, Yi-ming
;
Tian, Fu-yun
;
Li, Jin-hui
;
Xu, Chun-long
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/10/17
Triterpenoids with multi-skeletons as 11 beta-HSD1 inhibitors from Euphorbia sikkimensis
期刊论文
OAI收割
PHYTOCHEMISTRY, 2023, 卷号: 211, 页码: 12
作者:
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
Euphorbia sikkimensis family
Triterpenoids
11fl-HSD1 inhibitors
Molecular docking
Metabolic abnormalities
Iodine substitution compromises the aggregation-induced emission (AIE) property and enhances the biothiol sensitivity of quinoline-malononitrile-based fluorescent probes
期刊论文
OAI收割
DYES AND PIGMENTS, 2023, 卷号: 215, 页码: 111246
作者:
Zhu, Guo-Biao
;
Gao, Jie
;
Zhang, Min-Yu
;
He, Liu
;
Han, Hai-Hao
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
Fluorescent probes
Biothiol
Cell imaging
Aggregation-induced emission
Donor-Acceptor
Engineered nanomedicines block the PD-1/PD-L1 axis for potentiated cancer immunotherapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 10
作者:
Li, Jun-hao
;
Huang, Lu-jia
;
Zhou, Hui-ling
;
Shan, Yi-ming
;
Chen, Fang-min
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2022/08/16
cancer immunotherapy
immune checkpoint blockade
PD-1/PD-L1 axis
nanomedicine
nanosized drug delivery systems
Targeted delivery of maytansine to liver cancer cells via galactose-modified supramolecular two-dimensional glycomaterial
期刊论文
OAI收割
CHEMICAL COMMUNICATIONS, 2022, 卷号: 58, 期号: 32, 页码: 5029-5032
作者:
Hai-Na Xie
;
Yu-Yuan Chen
;
Guo-Biao Zhu
;
Hai-Hao Han
;
Xi-Le Hu
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/06/15
Phosphodiesters as GPR84 Antagonists for the Treatment of Ulcerative Colitis
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 5, 页码: 3991-4006
作者:
Chen, Lin-Hai
;
Zhang, Qing
;
Xiao, Yu-Feng
;
Fang, You-Chen
;
Xie, Xin
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/06/15
RBD conjugate vaccine with a built-in TLR1/2 agonist is highly immunogenic against SARS-CoV-2 and variants of concern
期刊论文
OAI收割
CHEMICAL COMMUNICATIONS, 2022, 卷号: 58, 期号: 13, 页码: 2120-2123
作者:
Zhou, Shi-Hao
;
Zhang, Ru-Yan
;
Zhang, Hai-Wei
;
Liu, Yan-Ling
;
Wen, Yu
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/06/15