机构

• 上海药物研究所 [25]

采集方式

• OAI收割 [25]

内容类型

• 期刊论文 [25]

发表日期

• 2023 [2]
• 2022 [1]
• 2021 [2]
• 2020 [1]
• 2016 [3]
• 2015 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共25条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 GPR84 regulates pulmonary inflammation by modulating neutrophil functions 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 8, 页码: 1665-1675 作者:  Wang, Si-wei   |  收藏  |  浏览/下载：3/0  |  提交时间：2024/03/27 GPR84  acute lung injury  inflammation  neutrophil  ROS  antagonist   Unsymmetrical Phosphodiesters as GPR84 Antagonists with High Blood Exposure for the Treatment of Lung Inflammation 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 8, 页码: 5820-5838 作者:  Li, Shao-Xian;  Wang, Si-Wei;  Chen, Lin-Hai;  Zhang, Qing;  Lu, Dan   |  收藏  |  浏览/下载：3/0  |  提交时间：2024/03/27 Loss of SIRT5 promotes bile acid-induced immunosuppressive microenvironment and hepatocarcinogenesis 期刊论文  OAI收割 JOURNAL OF HEPATOLOGY, 2022, 卷号: 77, 期号: 2, 页码: 453-466 作者:  Sun, Renqiang;  Zhang, Zhiyong;  Bao, Ruoxuan;  Guo, Xiaozhen;  Gu, Yuan   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/03/21 SIRT5  bile acid  macrophage polarization  immunosuppressive tumor microenvironment  liver cancer   GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Zhang, Qing;  Chen, Lin-hai;  Yang, Hui;  Fang, You-chen;  Wang, Si-wei   |  收藏  |  浏览/下载：53/0  |  提交时间：2022/01/18 GPR84  medium chain fatty acid receptor  GPCR  inflammatory bowel diseases  ulcerative colitis  NLRP3 inflammasome  macrophages   Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Zhou, Yu-bo;  Zhang, Yang-ming;  Huang, Hong-hui;  Shen, Li-jing;  Han, Xiao-feng   |  收藏  |  浏览/下载：67/0  |  提交时间：2021/11/04 multiple myeloma  HDAC inhibitor  bisthianostat  pharmacodynamics  pharmacokinetics  phase 1a clinical trial  antitumor drug   Synthesis and in Vitro and in Vivo Biological Evaluation of Tissue-Specific Bisthiazole Histone Deacetylase (HDAC) Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 2, 页码: 804-815 作者:  Zhang, Shu-Wei;  Gong, Chao-Jun;  Su, Ming-Bo;  Chen, Fei;  He, Ting   |  收藏  |  浏览/下载：20/0  |  提交时间：2020/07/01 Design and Synthesis of 2-Alkylpyrimidine-4,6-diol and 6-Alkylpyridine-2,4-diol as Potent GPR84 Agonists 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 7, 期号: 6, 页码: 579-583 作者:  Liu, Yang;  Zhang, Qing;  Chen, Lin-Hai;  Yang, Hui;  Lu, Wei   |  收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08 GPR84  agonists  2-alkylpyrimidine-4,6-diol  6-alkylpyridine-2,4-diol  structural modification   Design and synthesis of simple, yet potent and selective non-ring-A pyripyropene A-based inhibitors of acyl-coenzyme A: cholesterol acyltransferase 2 (ACAT2) 期刊论文  OAI收割 ORGANIC & BIOMOLECULAR CHEMISTRY, 2016, 卷号: 14, 期号: 2, 页码: 747-751 作者:  Zhan, Yang;  Zhang, Xiao-Wei;  Xiong, Ying   |  收藏  |  浏览/下载：40/0  |  提交时间：2019/01/08 Effect of a hepatitis B virus inhibitor, NZ-4, on capsid formation 期刊论文  OAI收割 ANTIVIRAL RESEARCH, 2016, 卷号: 125, 页码: 25-33 作者:  Yang, Li;  Wang, Ya-Juan;  Chen, Hai Jun;  Shi, Li-Ping;  Tong, Xian-Kun   |  收藏  |  浏览/下载：51/0  |  提交时间：2019/01/08 Anti-hepatitis B virus compound  Capsid formation  pgRNA packaging  Arg-rich domain I  Faster-migrating capsid   Discovery and structural optimization of 1-phenyl-3-(1-phenylethyl)urea derivatives as novel inhibitors of CRAC channel 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2015, 卷号: 36, 期号: 9, 页码: 1137-1144 作者:  Zhang, Hai-zhen;  Xu, Xiao-lan;  Chen, Hua-yan;  Ali, Sher;  Wang, Dan   |  收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08 CRAC channel  ORAI1  1-phenyl-3-(1-phenylethyl)urea  YM58483  high-throughput screening  IL-2 production  structure modification  SAR