机构

• 上海药物研究所 [62]

采集方式

• OAI收割 [62]

内容类型

• 期刊论文 [62]

发表日期

• 2023 [12]
• 2022 [4]
• 2021 [8]
• 2020 [9]
• 2019 [3]
• 2018 [11]
• 更多

学科主题

筛选

浏览/检索结果: 共62条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9 作者:  Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/11 COVID-19  Simnotrelvir  Safety  Pharmacokinetics  Healthy subjects   Tetrandrine synergizes with MAPK inhibitors in treating KRAS-mutant pancreatic ductal adenocarcinoma via collaboratively modulating the TRAIL-death receptor axis 期刊论文  OAI收割 PHARMACOLOGICAL RESEARCH, 2023, 卷号: 197, 页码: 12 作者:  Tang, Shuai;  Duan, Yichen;  Yuan, Tao;  Hu, Yutinh;  Yuan, Liang   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/11 KRAS  Pancreatic ductal adenocarcinoma  MAPK pathway  Tetrandrine  TRAIL  Death receptors   αExtractor: a system for automatic extraction of chemical information from biomedical literature 期刊论文  OAI收割 SCIENCE CHINA-LIFE SCIENCES, 2023, 页码: 4 作者:  Xiong, Jiacheng;  Liu, Xiaohong;  Li, Zhaojun;  Xiao, Hongzhong;  Wang, Guangchao   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/12/08 A pilot study of the differentiated landscape of peripheral blood mononuclear cells from children with incomplete versus complete Kawasaki disease 期刊论文  OAI收割 WORLD JOURNAL OF PEDIATRICS, 2023, 页码: 12 作者:  Sun, Shu-Na;  Zhou, Yan;  Fu, Xing;  Zheng, Yuan-Zheng;  Xie, Cao   |  收藏  |  浏览/下载：15/0  |  提交时间：2023/10/17 LogD7.4 prediction enhanced by transferring knowledge from chromatographic retention time, microscopic pKa and logP 期刊论文  OAI收割 JOURNAL OF CHEMINFORMATICS, 2023, 卷号: 15, 期号: 1, 页码: 13 作者:  Wang, Yitian;  Xiong, Jiacheng;  Xiao, Fu;  Zhang, Wei;  Cheng, Kaiyang   |  收藏  |  浏览/下载：13/0  |  提交时间：2023/10/17 logD7.4  Lipid solubility  Graph neural network  Molecular property prediction   Versatile Biocatalytic C(sp(3))-H Oxyfunctionalization for the Site- Selective and Stereodivergent Synthesis of & alpha;- and & beta;-Hydroxy Acids 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023, 页码: 9 作者:  Mao, Yingle;  Zhang, Weijie;  Fu, Zunyun;  Liu, Yanqiong;  Chen, Lin   |  收藏  |  浏览/下载：18/0  |  提交时间：2023/10/17 Asymmetric Synthesis  Biocatalysis  C(sp(3))-H Functionalization  Dioxygenases  Enzymes   The PIWI-specific insertion module helps load longer piRNAs for translational activation essential for male fertility 期刊论文  OAI收割 SCIENCE CHINA-LIFE SCIENCES, 2023, 页码: 23 作者:  Wang, Xin;  Lin, Di-Hang;  Yan, Yue;  Wang, An-Hui;  Liao, Jiaoyang   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/10/17 PIWI  piRNAs  PIWI-Ins  translational activation  spermatid development  male fertility   Asymmetric C1 Extension of Aldehydes through Biocatalytic Cascades for Stereodivergent Synthesis of Mandelic Acids 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023, 卷号: 62, 期号: 20 作者:  Liu, Yanqiong;  Fu, Zunyun;  Dong, Haihong;  Zhang, Jingxuan;  Mao, Yingle   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/03/27 Asymmetric C-1 Extension  Biocatalysis  Biocatalytic Cascades  (S)-4-Hydroxymandelate Synthase  Mandelic Acids   MolFilterGAN: a progressively augmented generative adversarial network for triaging AI-designed molecules 期刊论文  OAI收割 JOURNAL OF CHEMINFORMATICS, 2023, 卷号: 15, 期号: 1, 页码: 42 作者:  Liu, Xiaohong;  Zhang, Wei;  Tong, Xiaochu;  Zhong, Feisheng;  Li, Zhaojun   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/03/27 De novo molecule design  Generative models  Deep learning  Virtual screening  Compound quality control   Design, Synthesis, and Biological Evaluation of Bipyridazine Derivatives as Stimulator of Interferon Genes (STING) Receptor Agonists 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 5, 页码: 3327-3347 作者:  Shan, Bin;  Hou, Hui;  Zhang, Keke;  Li, Rui;  Shen, Chang   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/03/27