中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [73]
采集方式
OAI收割 [73]
内容类型
期刊论文 [72]
会议论文 [1]
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2023 [6]
2022 [4]
2021 [5]
2020 [11]
2019 [4]
2018 [7]
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Pharmacolo... [5]
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浏览/检索结果:
共73条,第1-10条
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专题:上海药物研究所
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Absorption, Distribution, Metabolism, and Excretion of [
14
C]BS1801, a Selenium-Containing Drug Candidate, in Rats
期刊论文
OAI收割
MOLECULES, 2023, 卷号: 28, 期号: 24, 页码: 16
作者:
Yang, Cheng
;
Xue, Mingzhen
;
He, Yifei
;
Yin, Hanwei
;
Yang, Chen
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/01/26
[C-14]BS1801
BS1801 (butaselen)
tissue distribution
metabolism
mass balance
selenium
αExtractor: a system for automatic extraction of chemical information from biomedical literature
期刊论文
OAI收割
SCIENCE CHINA-LIFE SCIENCES, 2023, 页码: 4
作者:
Xiong, Jiacheng
;
Liu, Xiaohong
;
Li, Zhaojun
;
Xiao, Hongzhong
;
Wang, Guangchao
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/08
Hyodeoxycholic acid ameliorates nonalcoholic fatty liver disease by inhibiting RAN-mediated PPARa nucleus-cytoplasm shuttling
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 18
作者:
Zhong, Jing
;
He, Xiaofang
;
Gao, Xinxin
;
Liu, Qiaohong
;
Zhao, Yu
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/12/08
Pharmacokinetics, Mass Balance, Tissue Distribution, and Metabolism of [
3
H]Catalpol in Rats: the Main Bioactive Component of
Rehmannia glutinosa
for the Treatment of Ischemic Stroke
期刊论文
OAI收割
CURRENT DRUG METABOLISM, 2023, 页码: 10
作者:
Ge, Xinyu
;
Zheng, Yuandong
;
He, Yifei
;
Chen, Chong
;
Yang, Chen
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/08
[H-3]catalpol
Rehmannia glutinosa
mass balance
tissue distribution
metabolism
intestinal flora
ischemic stroke.
Effect of an Herbal-Based Injection on 28-Day Mortality in Patients With Sepsis The EXIT-SEP Randomized Clinical Trial
期刊论文
OAI收割
JAMA INTERNAL MEDICINE, 2023, 卷号: 183, 期号: 7, 页码: 647-655
作者:
Liu, Songqiao
;
Yao, Chen
;
Xie, Jianfeng
;
Liu, Hong
;
Wang, Hongliang
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/03/27
MolFilterGAN: a progressively augmented generative adversarial network for triaging AI-designed molecules
期刊论文
OAI收割
JOURNAL OF CHEMINFORMATICS, 2023, 卷号: 15, 期号: 1, 页码: 42
作者:
Liu, Xiaohong
;
Zhang, Wei
;
Tong, Xiaochu
;
Zhong, Feisheng
;
Li, Zhaojun
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/03/27
De novo molecule design
Generative models
Deep learning
Virtual screening
Compound quality control
Mechanistic Study on the Species Differences in Excretion Pathway of HR011303 in Humans and Rats
期刊论文
OAI收割
DRUG METABOLISM AND DISPOSITION, 2022, 卷号: 50, 期号: 6, 页码: 809-818
作者:
Guo, Zitao
;
Liu, Mengling
;
Meng, Jian
;
Xue, Yaru
;
Huang, Qi
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/08/16
Pharmacokinetics, Mass Balance, and Metabolism of the Novel Urate Transporter 1 Inhibitor [14C]HR011303 in Humans: Metabolism Is Mediated Predominantly by UDP-Glucuronosyltransferase
期刊论文
OAI收割
DRUG METABOLISM AND DISPOSITION, 2022, 卷号: 50, 期号: 6, 页码: 798-808
作者:
Zheng, Yuandong
;
Zhang, Hua
;
Liu, Mengling
;
Li, Guangze
;
Ma, Sheng
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/08/16
Graph neural network approaches for drug-target interactions
期刊论文
OAI收割
CURRENT OPINION IN STRUCTURAL BIOLOGY, 2022, 卷号: 73, 页码: 102327
作者:
Zhang, Zehong
;
Chen, Lifan
;
Zhong, Feisheng
;
Wang, Dingyan
;
Jiang, Jiaxin
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/03/21
Multi-instance learning of graph neural networks for aqueous pK(a) prediction
期刊论文
OAI收割
BIOINFORMATICS, 2022, 卷号: 38, 期号: 3, 页码: 792-798
作者:
Xiong, Jiacheng
;
Li, Zhaojun
;
Wang, Guangchao
;
Fu, Zunyun
;
Zhong, Feisheng
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/06/15