机构

• 上海药物研究所 [14]

采集方式

• OAI收割 [14]

内容类型

• 期刊论文 [13]
• 会议论文 [1]

发表日期

• 2023 [3]
• 2020 [1]
• 2018 [1]
• 2017 [1]
• 2016 [2]
• 2015 [2]
• 更多

学科主题

筛选

浏览/检索结果: 共14条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9 作者:  Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/11 COVID-19  Simnotrelvir  Safety  Pharmacokinetics  Healthy subjects   Structure-Activity Relationship Study of 1H-Pyrrole-3-carbonitrile Derivatives as STING Receptor Agonists 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2023, 页码: 9 作者:  Shen, Chang;  Xu, Peijia;  Zhang, Changfa;  Su, Zhaoming;  Shan, Bin   |  收藏  |  浏览/下载：24/0  |  提交时间：2023/10/17 cGAS-STING signaling pathway  STING agonists  antitumor immunity  anti-infection immunity   Design, Synthesis, and Biological Evaluation of Bipyridazine Derivatives as Stimulator of Interferon Genes (STING) Receptor Agonists 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 5, 页码: 3327-3347 作者:  Shan, Bin;  Hou, Hui;  Zhang, Keke;  Li, Rui;  Shen, Chang   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/03/27 Species differences in the CYP3A-catalyzed metabolism of TPN729, a novel PDE5 inhibitor 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9 作者:  Tian, Qian-qian   |  收藏  |  浏览/下载：26/0  |  提交时间：2020/12/24 PDE5 inhibitor  TPN729  M3  species difference  pharmacokinetics  metabolite identification   Druggable negative allosteric site of P2X3 receptors 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 卷号: 115, 期号: 19, 页码: 4939-4944 作者:  Wang, Jin;  Wang, Yao;  Cui, Wen-Wen;  Huang, Yichen;  Yang, Yang   |  收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08 P2X3 receptors  allosteric inhibition  X-ray crystallography  AF-219  AF-353   The metabolic ER stress sensor IRE1 alpha suppresses alternative activation of macrophages and impairs energy expenditure in obesity 期刊论文  OAI收割 NATURE IMMUNOLOGY, 2017, 卷号: 18, 期号: 5, 页码: 519-529 作者:  Shan, Bo;  Wang, Xiaoxia;  Wu, Ying;  Xu, Chi;  Xia, Zhixiong   |  收藏  |  浏览/下载：44/0  |  提交时间：2019/01/08 Discovery and Rational Design of Natural-Product-Derived 2-Phenyl-3,4-dihydro-2H-benzo[f]chromen-3-amine Analogs as Novel and Potent Dipeptidyl Peptidase 4 (DPP-4) Inhibitors for the Treatment of Type 2 Diabetes 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 14, 页码: 6772-6790 作者:  Li, Shiliang;  Xu, Hongling;  Cui, Shichao;  Wu, Fangshu;  Zhang, Youli   |  收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08 Development of FTIR fingerprint for identification of armand clematis stem (Chuanmutong) and related herbs 期刊论文  OAI收割 Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2016, 卷号: 41, 期号: 8, 页码: 1485-1492 作者:  Gao, Shan-Shan;  Li, Jian-Rui;  Wu, Fang-Bin;  Wei, Xue-Min;  Bian, Jin-Hui   |  收藏  |  浏览/下载：10/0  |  提交时间：2019/01/08 Role for the endoplasmic reticulum stress sensor IRE1 alpha in liver regenerative responses 期刊论文  OAI收割 JOURNAL OF HEPATOLOGY, 2015, 卷号: 62, 期号: 3, 页码: 590-598 作者:  Liu, Yang;  Shao, Mengle;  Wu, Ying;  Yan, Cheng;  Jiang, Shan   |  收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08 Unfolded protein response  IRE1 alpha  Liver regeneration  Hepatocyte proliferation  STAT3   New Securinega alkaloids with anti-HIV activity from Flueggea virosa 期刊论文  OAI收割 RSC ADVANCES, 2015, 卷号: 5, 期号: 129, 页码: 107045-107053 作者:  Zhang, Hua;  Zhang, Chuan-Rui;  Han, Ying-Shan;  Wainberg, Mark A.;  Yue, Jian-Min   |  收藏  |  浏览/下载：10/0  |  提交时间：2019/01/08