中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [5]
武汉病毒研究所 [1]
昆明植物研究所 [1]
过程工程研究所 [1]
海洋研究所 [1]
上海生物化学与细胞生... [1]
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期刊论文 [11]
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2024 [2]
2023 [1]
2022 [4]
2020 [1]
2018 [2]
2017 [1]
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Second messenger 2'3'-cyclic GMP-AMP (2'3'-cGAMP): the cell autonomous and non-autonomous roles in cancer progression
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 10
作者:
Ma, Xiao-yu
;
Chen, Man-man
;
Meng, Ling-hua
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/02/27
CDNs
2'3'-cGAMP
cGAS-STING
tumor microenvironment
ENPP1
TREX1
Mixed micelles loaded with hesperidin protect against acetaminophen induced acute liver injury by inhibiting the mtDNA-cGAS-STING pathway
期刊论文
OAI收割
COLLOIDS AND SURFACES B-BIOINTERFACES, 2024, 卷号: 233, 页码: 12
作者:
Dong, Kehong
;
Sun, Yuxuan
;
Gao, Xintao
;
Wang, Jing
;
Wu, Xiaochen
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/04/07
Acetaminophen
Liver injury
Hesperidin
MtDNA
CGAS-STING
Structure-Activity Relationship Study of 1H-Pyrrole-3-carbonitrile Derivatives as STING Receptor Agonists
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2023, 页码: 9
作者:
Shen, Chang
;
Xu, Peijia
;
Zhang, Changfa
;
Su, Zhaoming
;
Shan, Bin
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2023/10/17
cGAS-STING signaling pathway
STING agonists
antitumor immunity
anti-infection immunity
Discovery and characterization of a novel cGAS covalent inhibitor for the treatment of inflammatory bowel disease
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 10
作者:
Song, Jia
;
Yang, Rui-rui
;
Chang, Jie
;
Liu, Ya-dan
;
Lu, Cheng-hao
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2022/11/11
cyclic GMP-AMP synthase
covalent inhibitor
inflammatory bowel disease
high-throughput screening
A Peritumorally Injected Immunomodulating Adjuvant Elicits Robust and Safe Metalloimmunotherapy against Solid Tumors
期刊论文
OAI收割
ADVANCED MATERIALS, 2022, 页码: 12
作者:
Zhang, Lingxiao
;
Zhao, Jing
;
Hu, Xi
;
Wang, Chenhan
;
Jia, Yingbo
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/02/24
immunogenic cell death
layered double hydroxide
nutritional metal ions
tumor microenvironment
vaccine adjuvants
Discovery of novel Thieno[2,3-d]imidazole derivatives as agonists of human STING for antitumor immunotherapy using systemic administration
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 238, 页码: 16
作者:
Niu, Jing
;
Bai, Hudagula
;
Li, Zizhou
;
Gao, Yuzhe
;
Zhang, Yan
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/08/16
STING
cGAS
Non-cyclic dinucleotides (non-CDNs)
Systemic administration
Antitumor immunotherapy
Single-Cell Transcriptome Analysis of Radiation Pneumonitis Mice
期刊论文
OAI收割
ANTIOXIDANTS, 2022, 卷号: 11
作者:
Yang, Miaomiao
;
Fan, Qiang
;
Hei, Tom K.
;
Chen, Guodong
;
Cao, Wei
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/12/23
radiation pneumonitis (RP)
single-cell RNA-seq (scRNA-seq)
mouse
oxidative stress
Small molecules targeting the innate immune cGAS-STING-TBK1 signaling pathway
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 12, 页码: 2272-2298
作者:
Ding, Chunyong
;
Song, Zilan
;
Shen, Ancheng
;
Chen, Tingting
;
Zhang, Ao
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/05/24
Immunotherapy
Anti-tumor
cGAS
STING
TBK1
Small molecule modulators
The Cyclopeptide Astin C Specifically Inhibits the Innate Immune CDN Sensor STING
期刊论文
OAI收割
CELL REPORTS, 2018, 卷号: 25, 期号: 12, 页码: 3405-+
作者:
Li, Senlin
;
Hong, Ze
;
Wang, Zhe
;
Li, Fei
;
Mei, Jiahao
  |  
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2019/03/29
The deubiquitinase CYLD is a specific checkpoint of the STING antiviral signaling pathway
期刊论文
OAI收割
PLOS PATHOGENS, 2018, 卷号: 14, 期号: 11, 页码: -
作者:
Zhang, Lele
;
Cui, Ye
;
Wang, Qiang
;
Li, Senlin
;
Liu, Heng
  |  
收藏
  |  
浏览/下载:90/0
  |  
提交时间:2019/04/28
Cyclic Gmp-amp
Tumor-suppressor Cyld
Cytosolic Dna Sensor
Nf-kappa-b
Innate
Adapter
Kinase
2nd-messenger
Recognition
Enzyme