机构

• 上海药物研究所 [6]

采集方式

• OAI收割 [6]

内容类型

• 期刊论文 [6]

发表日期

• 2019 [6]

学科主题

筛选

浏览/检索结果: 共6条，第1-6条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位    发表日期：2019     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Deciphering molecular mechanism behind conformational change of the Sao Paolo metallo-beta-lactamase 1 by using enhanced sampling 期刊论文  OAI收割 JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2019, 页码: 12 作者:  Chen, Jianzhong;  Wang, Jinan;  Pang, Laixue;  Wang, Wei;  Zhao, Juan   |  收藏  |  浏览/下载：23/0  |  提交时间：2020/07/01 Sao paolo metallo-beta-lactamase-1  REMD simulations  normal mode analysis  principal component analysis  drug resistance of antibiotics   TGR5 agonist ameliorates insulin resistance in skeletal muscles and improves glucose homeostasis in diabetic mice 期刊论文  OAI收割 METABOLISM-CLINICAL AND EXPERIMENTAL, 2019, 卷号: 99, 页码: 45-56 作者:  Huang, Suling;  Ma, Shanyao;  Ning, Mengmeng;  Yang, Wenji;  Ye, Yangliang   |  收藏  |  浏览/下载：30/0  |  提交时间：2020/07/01 TGR5  Glucose homeostasis  Insulin resistance  Skeletal muscle  Type 2 diabetes   SHR-A1403, a novel c-mesenchymal-epithelial transition factor (c-Met) antibody-drug conjugate, overcomes AZD9291 resistance in non-small cell lung cancer cells overexpressing c-Met 期刊论文  OAI收割 CANCER SCIENCE, 2019, 页码: 11 作者:  Tong, Mengya;  Gao, Mingzhao;  Xu, Yongping;  Fu, Li;  Li, Yun   |  收藏  |  浏览/下载：50/0  |  提交时间：2020/07/01 AZD9291  c-Met ADC  c-Met overexpression  resistance  SHR-A1403   The inhibitory mechanism of aurintricarboxylic acid targeting serine/threonine phosphatase Stp1 in Staphylococcus aureus: insights from molecular dynamics simulations 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 6, 页码: 850-858 作者:  Liu, Ting-ting;  Yang, Teng;  Gao, Mei-na;  Chen, Kai-xian;  Yang, Song   |  收藏  |  浏览/下载：9/0  |  提交时间：2020/07/01 antimicrobial resistance  Staphylococcus aureus  serine/threonine phosphatase  aurintricarboxylic acid  molecular dynamics simulations  flap subdomain   Preclinical characterization of SHR6390, a novel CDK 4/6 inhibitor, invitro and in human tumor xenograft models 期刊论文  OAI收割 CANCER SCIENCE, 2019, 卷号: 110, 期号: 4, 页码: 1420-1430 作者:  Long, Fei;  He, Ye;  Fu, Haoyu;  Li, Yun;  Bao, Xubin   |  收藏  |  浏览/下载：23/0  |  提交时间：2020/07/01 breast cancer  CDK 4/6  drug resistance  palbociclib  SHR6390   Targeting lipid metabolism to overcome EMT-associated drug resistance via integrin beta 3/FAK pathway and tumor-associated macrophage repolarization using legumain-activatable delivery 期刊论文  OAI收割 THERANOSTICS, 2019, 卷号: 9, 期号: 1, 页码: 265-278 作者:  Jin, Hongyue;  He, Yang;  Zhao, Pengfei;  Hu, Ying;  Tao, Jin   |  收藏  |  浏览/下载：97/0  |  提交时间：2019/01/08 Epithelial-mesenchymal transition  cholesterol metabolism  tumor-associated macrophages  simvastatin  drug resistance  legumain