中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
上海药物研究所 [18]
武汉病毒研究所 [5]
力学研究所 [1]
金属研究所 [1]
地理科学与资源研究所 [1]
成都山地灾害与环境研... [1]
更多
采集方式
OAI收割 [23]
iSwitch采集 [5]
内容类型
期刊论文 [28]
发表日期
2024 [2]
2023 [3]
2022 [4]
2021 [4]
2020 [6]
2019 [3]
更多
学科主题
筛选
浏览/检索结果:
共28条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
题名升序
题名降序
提交时间升序
提交时间降序
作者升序
作者降序
发表日期升序
发表日期降序
Targeting JMJD1C to selectively disrupt tumor T
reg
cell fitness enhances antitumor immunity
期刊论文
OAI收割
NATURE IMMUNOLOGY, 2024, 页码: 32
作者:
Long, Xuehui
;
Zhang, Sulin
;
Wang, Yuliang
;
Chen, Jingjing
;
Lu, Yanlai
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/03/25
Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRAS
G12D
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1147-1167
作者:
Zhou, Chuan
;
Fan, Zisheng
;
Gu, Yuejiao
;
Ge, Zhiming
;
Tao, Zhaofan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/02/27
Sequence-based drug design as a concept in computational drug design
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 21
作者:
Chen, Lifan
;
Fan, Zisheng
;
Chang, Jie
;
Yang, Ruirui
;
Hou, Hui
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/10/17
Discovery of a Potent, Cooperative, and Selective SOS1 PROTAC ZZ151 with In Vivo Antitumor Efficacy in KRAS-Mutant Cancers
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 6, 页码: 4197-4214
作者:
Zhou, Zehui
;
Zhou, Guizhen
;
Zhou, Chuan
;
Fan, Zisheng
;
Cui, Rongrong
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
Design, Synthesis, and Biological Evaluation of Bipyridazine Derivatives as Stimulator of Interferon Genes (STING) Receptor Agonists
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 5, 页码: 3327-3347
作者:
Shan, Bin
;
Hou, Hui
;
Zhang, Keke
;
Li, Rui
;
Shen, Chang
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
A Review of the Hydraulic Fracturing in Ductile Reservoirs: Theory, Simulation, and Experiment
期刊论文
OAI收割
PROCESSES, 2022, 卷号: 10, 期号: 10, 页码: 26
作者:
Zhu,Dawei
;
Han GF(韩国锋)
;
Zou,Honglan
;
Cui,Mingyue
;
Liang,Chong
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/11/21
hydraulic fracturing
ductile rock
plastic deformation
fracture toughness
fracture process zone
Discovery of the First-in-Class Agonist-Based SOS1 PROTACs Effective in Human Cancer Cells Harboring Various KRAS Mutations
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 5, 页码: 3923-3942
作者:
Zhou, Chuan
;
Fan, Zisheng
;
Zhou, Zehui
;
Li, Yupeng
;
Cui, Rongrong
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/06/15
Evolution of Interfacial Microstructure of Ni-Co Base Superalloy During Plastic Deformation Bonding and Its Bonding Mechanism
期刊论文
OAI收割
ACTA METALLURGICA SINICA, 2022, 卷号: 58, 期号: 2, 页码: 129-140
作者:
Ren Shaofei
;
Zhang Jianyang
;
Zhang Xinfang
;
Sun Mingyue
;
Xu Bin
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2022/07/01
Ni-Co base superalloy
plastic deformation bonding
dynamic recrystallization
Discovery of Pyrazolo[3,4-d]pyridazinone Derivatives as Selective DDR1 Inhibitors via Deep Learning Based Design, Synthesis, and Biological Evaluation
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 1, 页码: 103-119
作者:
Tan, Xiaoqin
;
Li, Chunpu
;
Yang, Ruirui
;
Zhao, Sen
;
Li, Fei
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2022/06/15
Active Learning for Drug Design: A Case Study on the Plasma Exposure of Orally Administered Drugs
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 22, 页码: 16838-16853
作者:
Ding, Xiaoyu
;
Cui, Rongrong
;
Yu, Jie
;
Liu, Tiantian
;
Zhu, Tingfei
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/06/15