中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共28条,第1-10条 帮助

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Targeting JMJD1C to selectively disrupt tumor Treg cell fitness enhances antitumor immunity 期刊论文  OAI收割
NATURE IMMUNOLOGY, 2024, 页码: 32
作者:  
Long, Xuehui;  Zhang, Sulin;  Wang, Yuliang;  Chen, Jingjing;  Lu, Yanlai
  |  收藏  |  浏览/下载:20/0  |  提交时间:2024/03/25
Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRASG12D 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1147-1167
作者:  
Zhou, Chuan;  Fan, Zisheng;  Gu, Yuejiao;  Ge, Zhiming;  Tao, Zhaofan
  |  收藏  |  浏览/下载:10/0  |  提交时间:2024/02/27
Sequence-based drug design as a concept in computational drug design 期刊论文  OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 21
作者:  
Chen, Lifan;  Fan, Zisheng;  Chang, Jie;  Yang, Ruirui;  Hou, Hui
  |  收藏  |  浏览/下载:17/0  |  提交时间:2023/10/17
Discovery of a Potent, Cooperative, and Selective SOS1 PROTAC ZZ151 with In Vivo Antitumor Efficacy in KRAS-Mutant Cancers 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 6, 页码: 4197-4214
作者:  
Zhou, Zehui;  Zhou, Guizhen;  Zhou, Chuan;  Fan, Zisheng;  Cui, Rongrong
  |  收藏  |  浏览/下载:2/0  |  提交时间:2024/03/27
Design, Synthesis, and Biological Evaluation of Bipyridazine Derivatives as Stimulator of Interferon Genes (STING) Receptor Agonists 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 5, 页码: 3327-3347
作者:  
Shan, Bin;  Hou, Hui;  Zhang, Keke;  Li, Rui;  Shen, Chang
  |  收藏  |  浏览/下载:2/0  |  提交时间:2024/03/27
A Review of the Hydraulic Fracturing in Ductile Reservoirs: Theory, Simulation, and Experiment 期刊论文  OAI收割
PROCESSES, 2022, 卷号: 10, 期号: 10, 页码: 26
作者:  
Zhu,Dawei;  Han GF(韩国锋);  Zou,Honglan;  Cui,Mingyue;  Liang,Chong
  |  收藏  |  浏览/下载:30/0  |  提交时间:2022/11/21
Discovery of the First-in-Class Agonist-Based SOS1 PROTACs Effective in Human Cancer Cells Harboring Various KRAS Mutations 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 5, 页码: 3923-3942
作者:  
Zhou, Chuan;  Fan, Zisheng;  Zhou, Zehui;  Li, Yupeng;  Cui, Rongrong
  |  收藏  |  浏览/下载:38/0  |  提交时间:2022/06/15
Evolution of Interfacial Microstructure of Ni-Co Base Superalloy During Plastic Deformation Bonding and Its Bonding Mechanism 期刊论文  OAI收割
ACTA METALLURGICA SINICA, 2022, 卷号: 58, 期号: 2, 页码: 129-140
作者:  
Ren Shaofei;  Zhang Jianyang;  Zhang Xinfang;  Sun Mingyue;  Xu Bin
  |  收藏  |  浏览/下载:34/0  |  提交时间:2022/07/01
Discovery of Pyrazolo[3,4-d]pyridazinone Derivatives as Selective DDR1 Inhibitors via Deep Learning Based Design, Synthesis, and Biological Evaluation 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 1, 页码: 103-119
作者:  
Tan, Xiaoqin;  Li, Chunpu;  Yang, Ruirui;  Zhao, Sen;  Li, Fei
  |  收藏  |  浏览/下载:33/0  |  提交时间:2022/06/15
Active Learning for Drug Design: A Case Study on the Plasma Exposure of Orally Administered Drugs 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 22, 页码: 16838-16853
作者:  
Ding, Xiaoyu;  Cui, Rongrong;  Yu, Jie;  Liu, Tiantian;  Zhu, Tingfei
  |  收藏  |  浏览/下载:30/0  |  提交时间:2022/06/15