中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [21]
宁波材料技术与工程研... [5]
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OAI收割 [43]
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期刊论文 [43]
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2023 [6]
2022 [6]
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Chemistry [1]
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Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 15
作者:
Kong, Linghui
;
Ning, Kuan
;
Liu, Xiao
;
Lu, Jiashuo
;
Chen, Baiyu
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
N-cyclopropylmethyl nornepenthone derivatives
derivatives
Structure-activity relationship
MOR antagonist
Functional reversal
Reversal of subtype-selectivity
Opioid use disorder
Hepatic glucuronyl C5-epimerase combats obesity by stabilising GDF15
期刊论文
OAI收割
JOURNAL OF HEPATOLOGY, 2023, 卷号: 79, 期号: 3, 页码: 14
作者:
He, Fei
;
Jiang, Haowen
;
Peng, Chang
;
Wang, Tingting
;
Xiao, Rongrong
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2023/10/17
Glucuronyl C5-epimerase
Growth differentiation factor-15
Obesity
Energy expenditure
Ubiquitination
Sequence-based drug design as a concept in computational drug design
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 21
作者:
Chen, Lifan
;
Fan, Zisheng
;
Chang, Jie
;
Yang, Ruirui
;
Hou, Hui
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/10/17
Multi-source underwater DOA estimation using PSO-BP neural network based on high-order cumulant optimization
期刊论文
OAI收割
CHINA COMMUNICATIONS, 2023, 页码: 18
作者:
Chen, Haihua
;
Zhang, Jingyao
;
Jiang, Bin
;
Cui, Xuerong
;
Zhou, Rongrong
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/04
Direction-of-arrival estimation
Estimation
Neural networks
Mathematical models
Training
Covariance matrices
Biological neural networks
particle swarm optimization (PSO) algorithm
PSO-BP neural network
gaussian colored noise
multiple sources
higher-order cumulant
Discovery of a Potent, Cooperative, and Selective SOS1 PROTAC ZZ151 with In Vivo Antitumor Efficacy in KRAS-Mutant Cancers
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 6, 页码: 4197-4214
作者:
Zhou, Zehui
;
Zhou, Guizhen
;
Zhou, Chuan
;
Fan, Zisheng
;
Cui, Rongrong
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
Design, Synthesis, and Biological Evaluation of Bipyridazine Derivatives as Stimulator of Interferon Genes (STING) Receptor Agonists
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 5, 页码: 3327-3347
作者:
Shan, Bin
;
Hou, Hui
;
Zhang, Keke
;
Li, Rui
;
Shen, Chang
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
Effects of comorbid posttraumatic stress disorder on cognitive dysfunction in Chinese male methamphetamine patients
期刊论文
OAI收割
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 2022, 卷号: 119, 页码: 8
作者:
Jiang, Wei
;
Tian, Yang
;
Fan, Fusheng
;
Fu, Fabing
;
Wei, Dejun
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/09/26
Methamphetamine
Posttraumatic stress disorder
Cognitive dysfunction
Drug addiction
Comorbidity
Depression in Chinese men with methamphetamine dependence: Prevalence, correlates and relationship with alexithymia
期刊论文
OAI收割
JOURNAL OF AFFECTIVE DISORDERS, 2022, 卷号: 319, 页码: 235-243
作者:
Li, Jiaxin
;
Jiang, Wei
;
Zhu, Rongrong
;
Fan, Fusheng
;
Fu, Fabing
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2022/11/08
Methamphetamine
Depression
Alexithymia
Craving
Drug addiction
Posttraumatic stress disorder in Chinese methamphetamine patients: Prevalence, demographics, and clinical correlates
期刊论文
OAI收割
AMERICAN JOURNAL ON ADDICTIONS, 2022, 页码: 4
作者:
Jiang, Wei
;
Tian, Yang
;
Fan, Fusheng
;
Fu, Fabing
;
Wei, Dejun
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/11/08
SLL-627 Is a Highly Selective and Potent ? Opioid Receptor (KOR) Agonist with an Unexpected Nonreduction in Locomotor Activity
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 16
作者:
Kong, Linghui
;
Shu, Xuelian
;
Tang, Siyuan
;
Ye, Rongrong
;
Sun, Huijiao
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2022/08/30