机构

• 上海药物研究所 [8]
• 化学研究所 [4]
• 西双版纳热带植物园 [2]
• 大连化学物理研究所 [2]
• 深圳先进技术研究院 [1]
• 青岛生物能源与过程研... [1]
• 更多

采集方式

• OAI收割 [19]

内容类型

• 期刊论文 [19]

发表日期

• 2023 [3]
• 2022 [1]
• 2021 [2]
• 2019 [1]
• 2018 [3]
• 2017 [4]
• 更多

学科主题

• Biochemist... [1]
• Cell Biolo... [1]
• Food Scien... [1]

筛选

浏览/检索结果: 共19条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025 作者:  Cheng, Jing;  Yan, Ziqin;  Jiang, Kailong;  Liu, Chen   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/02/19 A new class of potent liver injury protective compounds: Structural elucidation, total synthesis and bioactivity study 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 8, 页码: 3414-3424 作者:  Ji, Kailong;  Liu, Wei;  Yin, Weihang;  Kong, Xiangrong;  Xu, Honghong   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/10/17 Phychetins  Phyllanthus franchetianus  Structural elucidation  Total synthesis  Liver injury protection  Anti-inflammation   Discovery of toxoflavin,a potent IRE1α inhibitor acting through structure-dependent oxidative inhibition 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 1, 页码: 234 作者:  Liu Changmei;  Nie Litong;  Jiang Haini;  Xu Lei;  Zhang Kunzhi   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/05/22 endoplasmic reticulum stress  toxoflavin  reactive oxygen species  IRE1α  XBP1   Dual inhibition of CHK1/FLT3 enhances cytotoxicity and overcomes adaptive and acquired resistance in FLT3-ITD acute myeloid leukemia 期刊论文  OAI收割 LEUKEMIA, 2022, 页码: 11 作者:  Jiang, Kailong;  Li, Xuemei;  Wang, Chang;  Hu, Xiaobei;  Wang, Peipei   |  收藏  |  浏览/下载：19/0  |  提交时间：2023/04/10 Design, Synthesis, and Biological Evaluation of Orally Bioavailable CHK1 Inhibitors Active against Acute Myeloid Leukemia 期刊论文  OAI收割 CHEMMEDCHEM, 2021, 页码: 12 作者:  Jin, Tingting;  Wang, Peipei;  Long, Xiubing;  Jiang, Kailong;  Song, Pinrao   |  收藏  |  浏览/下载：125/0  |  提交时间：2021/05/24 CHK1 inhibitor  diaminopyrimidine  DNA damage response  oral bioavailability   Macrocyclic Nonapeptides Incorporating Uncharacterized Amino Acids with Inhibitory Effects on Th17 Differentiation 期刊论文  OAI收割 CCS CHEMISTRY, 2021, 卷号: 3, 期号: 2, 页码: 175 作者:  Ji Kailong;  Fan Yaoyue;  Kuok Hioha;  Liu Qunfang;  Li Ting   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/05/22 natural products  Glycosmis pentaphylla  cyclopeptides  Th17 differentiation inhibitors  RORγt LBD blockers   Discovery of (R)-5-((5-(1-methyl-1H-pyrazol-4-yl)-4-(methylamino) pyrimidin-2-yl)amino)-3-(piperidin-3-yloxy)picolinonitrile, a novel CHK1 inhibitor for hematologic malignancies 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 173, 页码: 44-62 作者:  Tong, Lexian;  Song, Pinrao;  Jiang, Kailong;  Xu, Lei;  Jin, Tingting   |  收藏  |  浏览/下载：24/0  |  提交时间：2020/07/01 CHK1 kinase inhibitor  Selectivity  Monotherapy  Hematologic malignancies   Side-Chain Impact on Molecular Orientation of Organic Semiconductor Acceptors: High Performance Nonfullerene Polymer Solar Cells with Thick Active Layer over 400 nm 期刊论文  OAI收割 ADVANCED ENERGY MATERIALS, 2018, 卷号: 8, 期号: 23 作者:  Luo, Zhenghui;  Sun, Chenkai;  Chen, Shanshan;  Zhang, Zhi-Guo;  Wu, Kailong   |  收藏  |  浏览/下载：35/0  |  提交时间：2019/04/09 Face-on Molecular Packing  Organic Semiconductor (N-os) Acceptors  Polymer Solar Cells  Power Conversion Efficiency  Side Chains   Data-Driven Hybrid Internal Temperature Estimation Approach for Battery Thermal Management 期刊论文  OAI收割 COMPLEXITY, 2018 作者:  Liu, Kailong;  Li, Kang;  Peng, Qiao;  Guo, Yuanjun;  Zhang, Li   |  收藏  |  浏览/下载：21/0  |  提交时间：2019/01/31 Bamboo shoot fiber improves insulin sensitivity in high-fat diet-fed mice 期刊论文  OAI收割 JOURNAL OF FUNCTIONAL FOODS, 2018, 卷号: 49, 期号: x, 页码: 510-517 作者:  Li, Xiufen;  Fu, Baiting;  Guo, Juan;  Ji, Kailong;  Xu, Youkai   |  收藏  |  浏览/下载：34/0  |  提交时间：2018/11/19 Dietary Fiber  Bamboo Shoot Fiber  Insulin Sensitivity  Insulin Signaling  Pgc-1 Alpha  Glucose Tolerance