中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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期刊论文 [1195]
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A novel strategy for treating oncogene-mutated tumors by targeting tumor microenvironment and synergistically enhancing anti-PD-1 immunotherapy
期刊论文
OAI收割
CANCER COMMUNICATIONS, 2024, 页码: 5
作者:
Liu, Yingqiang
;
Tong, Linjiang
;
Zhang, Mengge
;
Zhang, Qi
;
Liu, Qiupei
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/13
CFNet: Conditional filter learning with dynamic noise estimation for real image denoising
期刊论文
OAI收割
KNOWLEDGE-BASED SYSTEMS, 2024, 卷号: 284, 页码: 12
作者:
Zuo, Yifan
;
Yao, Wenhao
;
Zeng, Yifeng
;
Xie, Jiacheng
;
Fang, Yuming
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/03/26
Image denoising
Noise estimation
Conditional filter
Affine transform
Discovery of a novel GPR35 agonist with high and equipotent species potency for oral treatment of IBD
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 96, 页码: 12
作者:
Song, Zhaoxiang
;
Lu, Dan
;
Sun, Jun
;
Ye, Yangliang
;
Fang, Jiahui
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/01/16
GPR35
IBD
Lodoxamide
Quantification of Long-Range Dependence in Hydroclimatic Time Series: A Method-Comparison Study
期刊论文
OAI收割
JOURNAL OF APPLIED METEOROLOGY AND CLIMATOLOGY, 2023, 卷号: 62, 期号: 12, 页码: 1921-1942
作者:
Niu, Jingyi
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/01/04
Regression analysis
Statistical techniques
Time series
Stochastic models
Climate variability
Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764
作者:
Liu, Yingqiang
;
Zhan, Zhengsheng
;
Kang, Zhuang
;
Li, Mengyuan
;
Lv, Yongcong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/26
Small molecule inhibitor
Tumor microenvironment
Immune-checkpoint
immune-deficient mouse models
including temozolomide (TMZ) insensitive tumors. Notably
DRS: A deep reinforcement learning enhanced Kubernetes scheduler for microservice-based system
期刊论文
OAI收割
SOFTWARE-PRACTICE & EXPERIENCE, 2023, 页码: 25
作者:
Jian, Zhaolong
;
Xie, Xueshuo
;
Fang, Yaozheng
;
Jiang, Yibing
;
Lu, Ye
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/12/04
deep reinforcement learning
Kubernetes scheduler
microservice scheduling
resource awareness
Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 15
作者:
Kong, Linghui
;
Ning, Kuan
;
Liu, Xiao
;
Lu, Jiashuo
;
Chen, Baiyu
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
N-cyclopropylmethyl nornepenthone derivatives
derivatives
Structure-activity relationship
MOR antagonist
Functional reversal
Reversal of subtype-selectivity
Opioid use disorder
Neoproterozoic tectonic transition from subduction to back-arc extension along the western Yangtze Block, South China: Petrological evidence of Nb-enriched basalts and arc-type intrusive rocks
期刊论文
OAI收割
GONDWANA RESEARCH, 2023, 卷号: 122, 页码: 163-180
作者:
Zhu, Yu
;
Lai, Shao-Cong
;
Xie, Wan-li
;
Qin, Jiang-feng
;
Zhu, Ren-zhi
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/13
Nb-enriched basalt
Arc-type gabbros and diorites
Western Yangtze Block
Neoproterozoic
Subduction-related back-arc extension
A pilot study of the differentiated landscape of peripheral blood mononuclear cells from children with incomplete versus complete Kawasaki disease
期刊论文
OAI收割
WORLD JOURNAL OF PEDIATRICS, 2023, 页码: 12
作者:
Sun, Shu-Na
;
Zhou, Yan
;
Fu, Xing
;
Zheng, Yuan-Zheng
;
Xie, Cao
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/10/17
Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of ROR & gamma; antagonists
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 15
作者:
Mei, Lianghe
;
Xu, Lansong
;
Wu, Sanan
;
Wang, Yafang
;
Xu, Chao
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2023/10/17
Betulinic acid
ROR & gamma
Target identification
Rationale structure optimization
Anti-tumor effects
antagonists