机构

• 上海药物研究所 [108]
• 金属研究所 [26]
• 广州能源研究所 [16]
• 西北高原生物研究所 [9]
• 烟台海岸带研究所 [5]
• 生态环境研究中心 [4]
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采集方式

• OAI收割 [205]
• iSwitch采集 [3]

内容类型

• 期刊论文 [205]
• 会议论文 [3]

发表日期

• 2024 [17]
• 2023 [25]
• 2022 [28]
• 2021 [24]
• 2020 [20]
• 2019 [15]
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学科主题

• Biochemist... [2]
• Biology [1]
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筛选

浏览/检索结果: 共208条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Design, synthesis, and bioevaluation of SOS1 PROTACs derived from pyrido [2,3- d ]pyrimidin-7-one-based SOS1 inhibitor 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 107, 页码: 9 作者:  Wang, Kun;  Zhou, Zehui;  Ma, Xinyi;  Xu, Jiahang;  Xu, Wangyang   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/07/12 SOS1  KRAS mutation  PROTAC  Anti-cancer activity   Fine-tuning large language models for chemical text mining 期刊论文  OAI收割 CHEMICAL SCIENCE, 2024, 页码: 12 作者:  Zhang, Wei;  Wang, Qinggong;  Kong, Xiangtai;  Xiong, Jiacheng;  Ni, Shengkun   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/07/12 Generic protein-ligand interaction scoring by integrating physical prior knowledge and data augmentation modelling 期刊论文  OAI收割 NATURE MACHINE INTELLIGENCE, 2024, 页码: 21 作者:  Cao, Duanhua;  Chen, Geng;  Jiang, Jiaxin;  Yu, Jie;  Zhang, Runze   |  收藏  |  浏览/下载：3/0  |  提交时间：2024/07/12 In-situ vaccination immunotherapy of colorectal cancer with STING agonist-integrated supramolecular nanovectors 期刊论文  OAI收割 NANO TODAY, 2024, 卷号: 56, 页码: 13 作者:  Liu, Xiaoying;  Chen, Fangmin;  Saeed, Madiha;  Li, Xutong;  Zhang, Huijuan   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/07/12 Supramolecular nanovector  STING activation  Colorectal cancer  In -situ vaccination  Cancer immunotherapy   KinomeMETA: a web platform for kinome-wide polypharmacology profiling with meta-learning 期刊论文  OAI收割 NUCLEIC ACIDS RESEARCH, 2024, 页码: 9 作者:  Li, Zhaojun;  Qu, Ning;  Zhou, Jingyi;  Sun, Jingjing;  Ren, Qun   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/06/27 FuncPhos-STR: An integrated deep neural network for functional phosphosite prediction based on AlphaFold protein structure and dynamics 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2024, 卷号: 266, 页码: 11 作者:  Zhang, Guangyu;  Zhang, Cai;  Cai, Mingyue;  Luo, Cheng;  Zhu, Fei   |  收藏  |  浏览/下载：14/0  |  提交时间：2024/06/27 Functional phosphosite  Deep learning  AlphaFold protein structure  Dynamics  Protein protein interaction   Design, Synthesis, and Bioevaluation of Transcriptional Enhanced Assocciated Domain (TEAD) PROTAC Degraders 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 15, 期号: 5, 页码: 631-639 作者:  Li, Huajie;  Ge, Zhiming;  Lin, Kexin;  He, Wei;  Chu, Qinyu   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/06/27 Hippo pathway  TEAD  PROTAC  Selectivity   Siteselective and Enantiocomplementary C(sp3)-H Oxyfunctionalization for Synthesis of α-Hydroxy Acids 期刊论文  OAI收割 ACS CATALYSIS, 2024, 卷号: 14, 期号: 7, 页码: 4463-4470 作者:  Lian, Xin;  Mao, Yingle;  Fu, Zunyun;  Zhang, Weijie;  Chen, Jiayan   |  收藏  |  浏览/下载：3/0  |  提交时间：2024/05/07 biocatalysis  C(sp(3))-H functionalization  dioxygenases  asymmetric synthesis  alpha-hydroxyacids   Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1 期刊论文  OAI收割 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 卷号: 9, 期号: 1, 页码: 14 作者:  Xie, Xiong;  Lan, Qiaoshuai;  Zhao, Jinyi;  Zhang, Sulin;  Liu, Lu   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/05/07 DNA-PK-Mediated Cytoplasmic DNA Sensing Stimulates Glycolysis to Promote Lung Squamous Cell Carcinoma Malignancy and Chemoresistance 期刊论文  OAI收割 CANCER RESEARCH, 2024, 卷号: 84, 期号: 5, 页码: 688-702 作者:  Wang, Hui;  Zhang, Yanyang;  Tian, Yu;  Yang, Wanlin;  Wang, Yan   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/05/07