中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [84]
采集方式
OAI收割 [84]
内容类型
期刊论文 [84]
发表日期
2018 [84]
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发表日期:2018
专题:上海药物研究所
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Apoferritin nanocages loading mertansine enable effective eradiation of cancer stem-like cells in vitro
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2018, 卷号: 553, 期号: 1-2, 页码: 201-209
作者:
Tan, Tao
;
Wang, Yuqi
;
Wang, Hong
;
Cao, Haiqiang
;
Wang, Zhiwan
  |  
收藏
  |  
浏览/下载:137/0
  |  
提交时间:2019/01/08
Apoferritin
Mertansine
Cancer stem cells
Breast cancer
Nanocages
Drug delivery
The secretome engages STAT3 to favor a cytokine-rich microenvironment in mediating acquired resistance to FGFR inhibitors
期刊论文
OAI收割
Molecular cancer therapeutics, 2018, 卷号: 145, 页码: 817-842
作者:
Wang, Xinyi
;
Ai, Jing
;
Liu, Hongyan
;
Peng, Xia
;
Chen, Hui
  |  
收藏
  |  
浏览/下载:135/0
  |  
提交时间:2019/01/08
1,4-Diaryl-2-azetidinone
Combretastatin A-4
Tubulin polymerization
Antitumor
Disulfiram Copper Nanoparticles Prepared with a Stabilized Metal Ion Ligand Complex Method for Treating Drug-Resistant Prostate Cancers
期刊论文
OAI收割
ACS APPLIED MATERIALS & INTERFACES, 2018, 卷号: 10, 期号: 48, 页码: 41118-41128
作者:
Chen, Wu
;
Yang, Wen
;
Chen, Pengyu
;
Huang, Yongzhuo
;
Li, Feng
  |  
收藏
  |  
浏览/下载:96/0
  |  
提交时间:2019/01/08
disulfiram
copper diethyldithiocarbamate
drug resistance
prostate cancer
nanoparticle
drug delivery
paraptosis
Exploring molecular mechanism of allosteric inhibitor to relieve drug resistance of multiple mutations in HIV-1 protease by enhanced conformational sampling
期刊论文
OAI收割
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2018, 卷号: 86, 期号: 12, 页码: 1294-1305
作者:
Chen, Jianzhong
;
Peng, Cheng
;
Wang, Jinan
;
Zhu, Weiliang
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2019/01/08
allosteric inhibitor
HIV-1 protease
MM-GBSA
normal mode analysis
REMD
Remodeling Tumor-Associated Macrophages and Neovascularization Overcomes EGFR(T790M)-Associated Drug Resistance by PD-L1 Nanobody-Mediated Codelivery
期刊论文
OAI收割
SMALL, 2018, 卷号: 14, 期号: 47
作者:
Yin, Weimin
;
Yu, Xiaolu
;
Kang, Xuejia
;
Zhao, Yuge
;
Zhao, Pengfei
  |  
收藏
  |  
浏览/下载:100/0
  |  
提交时间:2019/01/08
antiangiogenesis
EGFR(T790M) mutation
PD-L1 nanobody
simvastatin
tumor-associated macrophage
Scutellarin alleviates blood-retina-barrier oxidative stress injury initiated by activated microglia cells during the development of diabetic retinopathy
期刊论文
OAI收割
Biochemical pharmacology, 2018, 卷号: 159, 页码: 82-95
作者:
Mei, Xiyu
;
Zhang, Tianyu
;
Ouyang, Hao
;
Lu, Bin
;
Wang, Zhengtao
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2018, 卷号: 9
作者:
Liu, Bin
;
Jiang, Shangwen
;
Li, Min
;
Xiong, Xuelian
;
Zhu, Mingrui
  |  
收藏
  |  
浏览/下载:109/0
  |  
提交时间:2019/01/08
Molecular modelling studies on cinnoline-based BTK inhibitors using docking and structure-based 3D-QSAR
期刊论文
OAI收割
SAR AND QSAR IN ENVIRONMENTAL RESEARCH, 2018, 卷号: 29, 期号: 11, 页码: 847-873
作者:
Li, R.
;
Du, Y.
;
Shen, J.
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
BTK inhibitors
B-cell malignancies
molecule docking
3D-QSAR
CoMFA
CoMSIA
Synthesis of novel tetrandrine derivatives and their inhibition against NSCLC A549 cells
期刊论文
OAI收割
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2018, 卷号: 20, 期号: 11, 页码: 1064-1074
作者:
Yang, Qian-Hao
;
Jiang, Cheng-Shi
;
Jin, Tao
;
Xu, Jin-Fang
;
Qu, Ting-Li
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
Tetrandrine derivatives
non-small cell lung carcinoma
NSCLC A549 cells
anticancer activities
Suzuki-Miyaura reaction
Discovery of JND3229 as a New EGFR(C797S) Mutant Inhibitor with In Vivo Monodrug Efficacy
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 9, 期号: 11, 页码: 1123-1127
作者:
Lu, Xiaoyun
;
Zhang, Tao
;
Zhu, Su-Jie
;
Xun, Qiuju
;
Tong, Lingjiang
  |  
收藏
  |  
浏览/下载:108/0
  |  
提交时间:2019/01/08
EGFR(C797s)
Clinical resistance
Fourth-generation nhibitors
Monodrug efficacy