中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [23]
采集方式
OAI收割 [23]
内容类型
期刊论文 [18]
项目 [5]
发表日期
2022 [23]
学科主题
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发表日期:2022
专题:上海药物研究所
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Discovery of 10H-Benzo[b]pyrido[2,3-e][1,4]oxazine AXL Inhibitors via Structure-Based Drug Design Targeting c-Met Kinase
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 15
作者:
Zhan, Zhengsheng
;
Ji, Yinchun
;
Su, Haixia
;
Fang, Chen
;
Peng, Xia
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2023/04/10
Structural insights into a shared mechanism of human STING activation by a potent agonist and an autoimmune disease-associated mutation
期刊论文
OAI收割
CELL DISCOVERY, 2022, 卷号: 8, 期号: 1, 页码: 17
作者:
Xie, Zuoquan
;
Wang, Zhen
;
Fan, Fengying
;
Zhou, Jinpei
;
Hu, Zhaoxue
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/04/10
Collaborative Innovation Cluster Projectof Shanghai Municipal Commission of Health and Family Planning[2020CXJQ02]
项目
OAI收割
项目编号: 2020CXJQ02, 资助机构: Collaborative Innovation Cluster Projectof Shanghai Municipal Commission of Health and Family Planning, 2022-
-
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/04/10
Discovery of 3-Aminopyrazole Derivatives as New Potent and Orally Bioavailable AXL Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 22, 页码: 15374-15390
作者:
Chan, Shingpan
;
Zhang, Yunong
;
Wang, Jie
;
Yu, Qiuchun
;
Peng, Xia
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/10
Structure-Activity relationship study of benzothiophene oxobutanoic acid analogues leading to novel stimulator of interferon gene (STING) agonists
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 241, 页码: 16
作者:
Shen, Ancheng
;
Li, Xiyuan
;
Zhang, Yan
;
Ma, Jing
;
Xiao, Ruoxuan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/04/10
Innate immunity
STING Agonists
Structural modification
Immuno-oncology
Epilepsy phenotype and response to KCNQ openers in mice harboring the Kcnq2 R207W voltage-sensor mutation
期刊论文
OAI收割
NEUROBIOLOGY OF DISEASE, 2022, 卷号: 174, 页码: 10
作者:
Tian, Fuyun
;
Cao, Birong
;
Xu, Haiyan
;
Zhan, Li
;
Nan, Fajun
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/12/13
KCNQ2
Epilepsy
Mouse model
HN37 (pynegabine)
The quantitative proteomic analysis reveals schisantherin a prevents liver fibrosis through regulating extracellular matrix organization
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2022, 卷号: 480, 页码: 8
作者:
Lu, Qi
;
Huang, Hui
;
Liu, Qian
;
Wang, Yuqiu
;
Meng, Qian
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/11/11
Collaborative Innovation Cluster Project of Shanghai Municipal Commission of Health and Family Planning (China)[2019CXJQ02]
项目
OAI收割
项目编号: 2019CXJQ02, 资助机构: Collaborative Innovation Cluster Project of Shanghai Municipal Commission of Health and Family Planning (China), 2022-
-
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/08/30
Discovery of a potent and selective proteolysis targeting chimera (PROTAC) degrader of NSD3 histone methyltransferase
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 239, 页码: 18
作者:
Sun, Yaoliang
;
Zhang, Ying
;
Chen, Xiaoai
;
Yu, Aisong
;
Du, Wenhao
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2022/08/30
NSD3
PROTAC
Degrader
Methyltransferase
Discovery of Novel Imidazo[4,5-c]quinoline Derivatives to Treat Inflammatory Bowel Disease (IBD) by Inhibiting Multiple Proinflammatory Signaling Pathways and Restoring Intestinal Homeostasis
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 21
作者:
Liang, Xuewu
;
Xie, Yongle
;
Liu, Xuyi
;
Xu, Hui
;
Ren, Hairu
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/11/11