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浏览/检索结果: 共13条，第1-10条 帮助

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Design, synthesis and pharmacological evaluation of 2,3-dihydrobenzo-furan IRAK4 inhibitors for the treatment of diffuse large B-cell lymphoma 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256, 页码: 16
作者:  Chen, Yun;  Ning, Yi;  Chen, Zhiwei;  Xue, Yaping;  Wu, Qingyun
  |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17
Design, synthesis and biological evaluation of KRASG12C-PROTACs 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 78, 页码: 14
作者:  Zhang, Xiaoyi;  Zhao, Tong;  Sun, Minghao;  Li, Pei;  Lai, Mengzhen
  |  收藏  |  浏览/下载：13/0  |  提交时间：2023/04/10
Structural insights into a shared mechanism of human STING activation by a potent agonist and an autoimmune disease-associated mutation 期刊论文  OAI收割
CELL DISCOVERY, 2022, 卷号: 8, 期号: 1, 页码: 17
作者:  Xie, Zuoquan;  Wang, Zhen;  Fan, Fengying;  Zhou, Jinpei;  Hu, Zhaoxue
  |  收藏  |  浏览/下载：21/0  |  提交时间：2023/04/10
Discovery and structure - activity relationship exploration of pyrazolo [1,5-a]pyrimidine derivatives as potent FLT3-ITD inhibitors 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 48, 页码: 13
作者:  Chen, Yun;  Bai, Gang;  Li, Yan;  Ning, Yi;  Cao, Sufen
  |  收藏  |  浏览/下载：58/0  |  提交时间：2021/12/01
Design, Synthesis, and Biological Evaluation of IRAK4-Targeting PROTACs 期刊论文  OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 12, 期号: 1, 页码: 82-87
作者:  Chen, Yun;  Ning, Yi;  Bai, Gang;  Tong, Linjiang;  Zhang, Tao
  |  收藏  |  浏览/下载：41/0  |  提交时间：2021/05/24
DW14006 as a direct AMPK alpha 1 activator improves pathology of AD model mice by regulating microglial phagocytosis and neuroinflammation 期刊论文  OAI收割
BRAIN BEHAVIOR AND IMMUNITY, 2020, 卷号: 90, 页码: 55-69
作者:  Lv, Jianlu;  Wang, Wei;  Zhu, Xialin;  Xu, Xiaoju;  Yan, Qiuying
  |  收藏  |  浏览/下载：29/0  |  提交时间：2020/12/21
DW14006 as a Direct AMPK alpha Activator Ameliorates Diabetic Peripheral Neuropathy in Mice 期刊论文  OAI收割
DIABETES, 2020, 卷号: 69, 期号: 9, 页码: 1974-1988
作者:  Xu, Xu;  Wang, Wei;  Wang, Zhengyu;  Lv, Jianlu;  Xu, Xiaoju
  |  收藏  |  浏览/下载：23/0  |  提交时间：2020/12/24
Design and synthesis of Imidazo[1,2-b]pyridazine IRAK4 inhibitors for the treatment of mutant MYD88 L265P diffuse large B-cell lymphoma 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 190, 页码: 14
作者:  Chen, Yun;  Bai, Gang;  Ning, Yi;  Cai, Shi;  Zhang, Tao
  |  收藏  |  浏览/下载：40/0  |  提交时间：2020/07/01
TSPA as a novel ATF6 alpha translocation inducer efficiently ameliorates insulin sensitivity restoration and glucose homeostasis in db/db mice 期刊论文  OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 499, 期号: 4, 页码: 948-953
作者:  Zhou, Tingting;  Cheng, Yanhua;  Yan, Wenzhong;  Shi, Xiaofan;  Xu, Xin
  |  收藏  |  浏览/下载：32/0  |  提交时间：2019/01/08
Discovery of cycloalkyl-fused N-thiazol-2-yl-benzamides as tissue non-specific glucokinase activators: Design, synthesis, and biological evaluation 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 139, 页码: 128-152
作者:  Wang, Zhengyu;  Shi, Xiaofan;  Zhang, Huan;  Yu, Liang;  Cheng, Yanhua
  |  收藏  |  浏览/下载：33/0  |  提交时间：2019/01/08