中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [29]
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OAI收割 [29]
内容类型
期刊论文 [29]
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2022 [1]
2021 [4]
2020 [1]
2019 [1]
2018 [6]
2014 [4]
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Medical La... [1]
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共29条,第1-10条
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内容类型:期刊论文
专题:上海药物研究所
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Simultaneous determination of almonertinib and its active metabolite HAS-719 in human plasma by LC-MS/MS: Evaluation of pharmacokinetic interactions
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2022, 卷号: 1197, 页码: 7
作者:
Liu, Lu
;
Yang, Le
;
Li, Wei
;
Chen, Xiaoyan
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/08/16
Almonertinib
LC -MS
MS
Active metabolite (HAS-719)
Pharmacokinetic drug-drug interaction
Itraconazole and rifampicin, as CYP3A modulators but not P-gp modulators, affect the pharmacokinetics of almonertinib and active metabolite HAS-719 in healthy volunteers
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Liu, Lu
;
Li, Wei
;
Yang, Le
;
Guo, Zi-tao
;
Xue, Hao
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/08/17
almonertinib
itraconazole
rifampicin
drug metabolism
drug interaction
CYP3A
P-gp
pharmacokinetics
Cytochrome P450-Mediated Metabolism and CYP Inhibition for the Synthetic Peroxide Antimalarial OZ439
期刊论文
OAI收割
ACS INFECTIOUS DISEASES, 2021, 卷号: 7, 期号: 7, 页码: 1885-1893
作者:
Shackleford, David M.
;
Chiu, Francis C. K.
;
Katneni, Kasiram
;
Blundell, Scott
;
McLaren, Jenna
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/11/04
OZ439 (artefenomel)
malaria
metabolite identification
cytochrome P450 metabolism
cytochrome P450 inhibition
time-dependent inhibition
Quantification of Usaramine and its N-Oxide Metabolite in Rat Plasma Using Liquid Chromatography-Tandem Mass Spectrometry
期刊论文
OAI收割
JOURNAL OF ANALYTICAL TOXICOLOGY, 2021, 卷号: 46, 期号: 5, 页码: 512-518
作者:
Lin, Feifei
;
Ma, Yan
;
Pan, Anni
;
Ye, Yang
;
Liu, Jia
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2022/08/16
Pharmacokinetic Drug-drug Interaction of Antibiotics Used in Sepsis Care in China
期刊论文
OAI收割
CURRENT DRUG METABOLISM, 2021, 卷号: 22, 期号: 1, 页码: 5-23
作者:
Yu, Xuan
;
Chu, Zixuan
;
Li, Jian
;
He, Rongrong
;
Wang, Yaya
  |  
收藏
  |  
浏览/下载:95/0
  |  
提交时间:2021/05/24
Pharmacokinetics
drug-drug interaction
antibiotic
sepsis
transporter
enzyme
Species differences in the CYP3A-catalyzed metabolism of TPN729, a novel PDE5 inhibitor
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Tian, Qian-qian
;
Zhu, Yun-ting
;
Diao, Xing-xing
;
Zhang, Xiang-lei
;
Xu, Ye-chun
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/12/24
PDE5 inhibitor
TPN729
M3
species difference
pharmacokinetics
metabolite identification
Intravenous formulation of Panax notoginseng root extract: human pharmacokinetics of ginsenosides and potential for perpetrating drug interactions
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1351-1363
作者:
Pintusophon, Salisa
;
Niu, Wei
;
Duan, Xiao-na
;
Olaleye, Olajide E.
;
Huang, Yu-hong
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
ginsenoside
cytochrome P450 3A
organic anion-transporting polypeptide 1B3
herbal medicine-drug interactions
XueShuanTong
Panax notoginseng
A sensitive LC-MS/MS method for the determination of triptolide and its application to pharmacokinetic research in rats
期刊论文
OAI收割
Biomedical chromatography : BMC, 2018, 页码: e4422
作者:
Xu, Ye
;
Chen, Xiaoyan
;
Zhong, Dafang
  |  
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2019/01/08
CYP3A4 inducer and inhibitor strongly affect the pharmacokinetics of triptolide and its derivative in rats
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 8, 页码: 1386-1392
作者:
Xu, Ye
;
Zhang, Yi-fan
;
Chen, Xiao-yan
;
Zhong, Da-fang
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
triptolide
(5R)-5-hydroxytriptolide
CYP3A4
ritonavir
dexamethasone
pharmacokinetics
immunosuppressant
traditional Chinese medicine
Pharmacokinetics and disposition of anlotinib, an oral tyrosine kinase inhibitor, in experimental animal species
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 6, 页码: 1048-1063
作者:
Zhong, Chen-chun
;
Chen, Feng
;
Yang, Jun-ling
;
Jia, Wei-wei
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2019/01/08
anlotinib
tyrosine kinase inhibitor
absorption
distribution
metabolism
excretion
pharmacokinetics