机构

• 上海药物研究所 [104]

采集方式

• OAI收割 [104]

内容类型

• 期刊论文 [93]
• 学位论文 [6]
• 会议论文 [5]

发表日期

• 2023 [8]
• 2022 [12]
• 2021 [8]
• 2020 [8]
• 2019 [5]
• 2018 [8]
• 更多

学科主题

• Pharmacolo... [1]

筛选

浏览/检索结果: 共104条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序题名升序题名降序作者升序作者降序发表日期升序发表日期降序 Targeting ST8SIA6-AS1 counteracts KRASG12C inhibitor resistance through abolishing the reciprocal activation of PLK1/c-Myc signaling 期刊论文  OAI收割 EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2023, 卷号: 12, 期号: 1, 页码: 22 作者:  Wang, Yafang;  Yao, Mingyue;  Li, Cheng;  Yang, Kexin;  Qin, Xiaolong   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/01/26 KRAS(G12C)  c-Myc  PLK1  LncRNA  ST8SIA6-AS1  Drug resistance   Otilonium Bromide acts as a selective USP28 inhibitor and exhibits cytotoxic activity against multiple human cancer cell lines 期刊论文  OAI收割 BIOCHEMICAL PHARMACOLOGY, 2023, 卷号: 215, 页码: 14 作者:  Xu, Zhuo;  Wang, Hui;  Meng, Qian;  Ding, Yiluan;  Zhu, Mengying   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 Otilonium Bromide  Deubiquitinase  USP28  Selective inhibitor   Rational Design of RNA Demethylase FTO Inhibitors with Enhanced Antileukemia Drug-Like Properties 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 22 作者:  Xiao, Pan;  Duan, Zongliang;  Liu, Zeyu;  Chen, Liang;  Zhang, Deyan   |  收藏  |  浏览/下载：16/0  |  提交时间：2023/10/17 Structure-based discovery of potent USP28 inhibitors derived from Vismodegib 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 15 作者:  Zhou, Di;  Xu, Zhuo;  Huang, Yaodong;  Wang, Hui;  Zhu, Xiaoli   |  收藏  |  浏览/下载：25/0  |  提交时间：2023/10/17 USP28  Structure-based  Vismodegib derivatives  Structure-activity relationships  c-Myc   Elevated Nuclear PHGDH Synergistically Functions with cMyc to Reshape the Immune Microenvironment of Liver Cancer 期刊论文  OAI收割 ADVANCED SCIENCE, 2023, 卷号: 10, 期号: 17 作者:  Zhu, Hongwen;  Yu, Hua;  Zhou, Hu;  Zhu, Wencheng;  Wang, Xiongjun   |  收藏  |  浏览/下载：0/0  |  提交时间：2024/03/27 cMyc  CXCL1  IL8  liver cancer  neutrophil  nuclear PHGDH   Dysregulation of iron homeostasis by TfR-1 renders EZH2 wild type diffuse large B-cell lymphoma resistance to EZH2 inhibition 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12 作者:  Yu, Lei;  Wang, Ya-fang;  Xiao, Jian;  Shen, Qian-qian;  Chi, Shuai-shuai   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 diffuse large B-cell lymphoma  EZH2  TfR-1  GPX4  ferroptosis  HH2853   Discovery of new small molecule inhibitors of the BPTF bromodomain 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 134, 页码: 106453 作者:  Liang, Xiaochen;  Cao, Yu;  Duan, Zhe;  Wang, Mingchen;  Zhang, Naixia   |  收藏  |  浏览/下载：3/0  |  提交时间：2024/03/27 BPTF bromodomain  BPTF inhibitors  HTRF  c-Myc   Discovery of LL-K8-22: A Selective, Durable, and Small-Molecule Degrader of the CDK8-Cyclin C Complex 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 7, 页码: 4932-4951 作者:  Wang, Mingyu;  Lin, Rongkun;  Li, Jiacheng;  Suo, Yuying;  Gao, Jing   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/10/17 Dual inhibition of CHK1/FLT3 enhances cytotoxicity and overcomes adaptive and acquired resistance in FLT3-ITD acute myeloid leukemia 期刊论文  OAI收割 LEUKEMIA, 2022, 页码: 11 作者:  Jiang, Kailong;  Li, Xuemei;  Wang, Chang;  Hu, Xiaobei;  Wang, Peipei   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/04/10 A potent PGK1 antagonist reveals PGK1 regulates the production of IL-1 beta and IL-6 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 11, 页码: 4180-4192 作者:  Liao, Liping;  Dang, Wenzhen;  Lin, Tingting;  Yu, Jinghua;  Liu, Tonghai   |  收藏  |  浏览/下载：16/0  |  提交时间：2023/04/10 Glycolysis  Phosphoglycerate kinase 1  Macrophages  NRF2  Inflammation