中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
深圳先进技术研究院 [18]
上海药物研究所 [18]
近代物理研究所 [11]
沈阳自动化研究所 [9]
昆明植物研究所 [8]
地理科学与资源研究所 [6]
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OAI收割 [159]
内容类型
期刊论文 [150]
专利 [5]
会议论文 [4]
发表日期
2018 [159]
学科主题
Materials ... [4]
Physics [4]
Engineerin... [2]
Materials ... [2]
Multidisci... [2]
Paleontolo... [2]
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浏览/检索结果:
共159条,第1-10条
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存缴方式:oaiharvest
发表日期:2018
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Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3693-3699
作者:
Zhu, Kongkai
;
Song, Jia-Li
;
Tao, Hong-Rui
;
Cheng, Zhi-Qiang
;
Jiang, Cheng-Shi
  |  
收藏
  |  
浏览/下载:100/0
  |  
提交时间:2019/01/08
Pharmacophore combination
Isoquinoline
PRMT5 inhibitor
Molecular docking
Molecular dynamics simulation
Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
作者:
Liu, Xuesong
;
Wang, Beilei
;
Chen, Cheng
;
Jiang, Zongru
;
Hu, Chen
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/01/11
ABL kinase
Kinase inhibitor
ABL mutant
CML
Comparative study of trophic and elemental characteristics of zooplankton in deep (500-3500 m) and shallow (0-200 m) layers
期刊论文
OAI收割
DEEP-SEA RESEARCH PART I-OCEANOGRAPHIC RESEARCH PAPERS, 2018, 卷号: 142, 页码: 107-115
作者:
Chen, Lei
;
Li, Chaolun
;
Tao, Zhencheng
;
Dai, Luping
;
Wang, Yanqing
  |  
收藏
  |  
浏览/下载:76/0
  |  
提交时间:2019/07/15
Deep and shallow sea
Trophic position
Trophic niche overlap
Ecological stoichiometry
Comparative study of trophic and elemental characteristics of zooplankton in deep (500-3500 m) and shallow (0-200 m) layers
期刊论文
OAI收割
DEEP-SEA RESEARCH PART I-OCEANOGRAPHIC RESEARCH PAPERS, 2018, 卷号: 142, 页码: 107-115
作者:
Chen, Lei
;
Li, Chaolun
;
Tao, Zhencheng
;
Dai, Luping
;
Wang, Yanqing
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/05/15
Deep and shallow sea
Trophic position
Trophic niche overlap
Ecological stoichiometry
Identification of 5-benzylidene-2-phenylthiazolones as potent PRMT5 inhibitors by virtual screening, structural optimization and biological evaluations
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2018, 卷号: 81, 页码: 289-298
作者:
Zhu, Kongkai
;
Tao, Hongrui
;
Song, Jia-Li
;
Jin, Lu
;
Zhang, Yuanyuan
  |  
收藏
  |  
浏览/下载:129/0
  |  
提交时间:2019/01/08
PRMT5 inhibitor
Arginine methylation
Virtual screening
Molecular docking
Molecular dynamics simulation
一种电气设备局放源定位装置及定位方法
专利
OAI收割
专利号: CN106093715B, 申请日期: 2018-11-27, 公开日期: 2018-11-27
作者:
宁涛
;
谢庆
;
王涛
;
喻集文
;
刘帆
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/12/24
Synthesis of novel tetrandrine derivatives and their inhibition against NSCLC A549 cells
期刊论文
OAI收割
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2018, 卷号: 20, 期号: 11, 页码: 1064-1074
作者:
Yang, Qian-Hao
;
Jiang, Cheng-Shi
;
Jin, Tao
;
Xu, Jin-Fang
;
Qu, Ting-Li
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
Tetrandrine derivatives
non-small cell lung carcinoma
NSCLC A549 cells
anticancer activities
Suzuki-Miyaura reaction
Does PPP Matter to Sustainable Tourism Development? An Analysis of the Spatial Effect of the Tourism PPP Policy in China
期刊论文
OAI收割
SUSTAINABILITY, 2018, 卷号: 10, 期号: 11, 页码: 15
作者:
Cheng, Zhe
;
Yang, Zhenshan
;
Gao, Huina
;
Tao, Hui
;
Xu, Ming
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/05/23
tourism sustainable development
policy evaluation
spatial effect
PPP (Public Private Partnership)
Silicon detector array for radioactive beam experiments at HIRFL-RIBLL
期刊论文
OAI收割
NUCLEAR SCIENCE AND TECHNIQUES, 2018, 卷号: 29
作者:
Duan, Fang-Fang
;
Yang, Yan-Yun
;
Hu, Bi-Tao
;
Wang, Jian-Song
;
Gao, Zhi-Hao
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2019/03/27
Direct nuclear reactions
Silicon detector array
Radioactive ion beams
Monte Carlo simulation