中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [32]
采集方式
OAI收割 [32]
内容类型
期刊论文 [32]
发表日期
2022 [32]
学科主题
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浏览/检索结果:
共32条,第1-10条
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存缴方式:oaiharvest
发表日期:2022
专题:上海药物研究所
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Hiding Payload Inside the IgG Fc Cavity Significantly Enhances the Therapeutic Index of Antibody-Drug Conjugates
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 16
作者:
Shi, Wei
;
Zhang, Jianxin
;
Liu, Liya
;
Li, Wanzhen
;
Liu, Zhi
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/04/10
Chemotherapy-induced phlebitis via the GBP5/NLRP3 inflammasome axis and the therapeutic effect of aescin
期刊论文
OAI收割
BRITISH JOURNAL OF PHARMACOLOGY, 2022, 页码: 16
作者:
Liu, Peng
;
Ye, Lichun
;
Ren, Yongshen
;
Zhao, Guodun
;
Zhang, Yun
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2023/04/10
aescin
GBP5
NLRP3 inflammasome
phlebitis
vinorelbine
Fused-ring alpha-pyrones from intramolecular C-H activation and their lipids-lowering activity associated with LXR-IDOL-LDLR axis regulation
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 244, 页码: 11
作者:
Mao, Yingle
;
Li, Jiaomeng
;
Tang, Chunping
;
Ma, Biao
;
Xu, Zhijian
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/04/10
C-H activation
One-pot intramolecular cyclization
?-Pyrone derivatives
LDL uptaking
LXR-IDOL-LDLR axis
In vivo lipids-lowering effect
DCZ19931, a novel multi-targeting kinase inhibitor, inhibits ocular neovascularization
期刊论文
OAI收割
SCIENTIFIC REPORTS, 2022, 卷号: 12, 期号: 1, 页码: 15
作者:
Zhang, Huiying
;
Li, Bo
;
Ding, Jingjuan
;
Ye, Rong
;
Xu, Zhijian
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
Suppression of Pathological Ocular Neovascularization by a Small Molecular Multi-Targeting Kinase Inhibitor, DCZ19903
期刊论文
OAI收割
TRANSLATIONAL VISION SCIENCE & TECHNOLOGY, 2022, 卷号: 11, 期号: 12, 页码: 15
作者:
Ding, Jingjuan
;
Li, Bo
;
Zhang, Huiying
;
Xu, Zhijian
;
Zhang, Qiuyang
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/10/17
ocular neovascularization
DCZ19903
multitarget kinase inhibitor
network pharmacology
MAPK signaling pathway
Antiviral drug design based on structural insights into the N-terminal domain and C-terminal domain of the SARS-CoV-2 nucleocapsid protein
期刊论文
OAI收割
SCIENCE BULLETIN, 2022, 卷号: 67, 期号: 22, 页码: 2327-2335
作者:
Luan, Xiaodong
;
Li, Xinming
;
Li, Yufan
;
Su, Gengchen
;
Yin, Wanchao
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2023/04/10
SARS-CoV-2
Nucleocapsid protein
N-terminal domain
Ceftriaxone sodium
Surface Modifiers on Composite Particles for Direct Compaction
期刊论文
OAI收割
PHARMACEUTICS, 2022, 卷号: 14, 期号: 10, 页码: 41
作者:
Chen, Fu-Cai
;
Liu, Wen-Jun
;
Zhu, Wei-Feng
;
Yang, Ling-Yu
;
Zhang, Ji-Wen
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2022/12/13
direct compaction
particle structure
surface modifier
co-processing
Stable, Bright, and Long-Fluorescence-Lifetime Dyes for Deep-Near- Infrared Bioimaging
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2022, 页码: 12
作者:
Li, Jin
;
Dong, Yan
;
Wei, Ruwei
;
Jiang, Guanyu
;
Yao, Cheng
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2022/08/30
A Traceless Site-Specific Conjugation on Native Antibodies Enables Efficient One-Step Payload Assembly
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 页码: 11
作者:
Zeng, Yue
;
Shi, Wei
;
Dong, Qian
;
Li, Wanzhen
;
Zhang, Jianxin
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2022/08/30
Acyl Transfer
Anti-Tumor
One-Step Synthesis
Site-Specific ADCs
Thioester
Selection of internal reference gene for normalization of reverse transcription-quantitative polymerase chain reaction analysis in Mycoplasma hyopneumoniae
期刊论文
OAI收割
FRONTIERS IN VETERINARY SCIENCE, 2022, 卷号: 9, 页码: 11
作者:
Li, Shiyang
;
Zhou, Yanqing
;
Yuan, Ting
;
Feng, Zhixin
;
Zhang, Zhenzhen
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2022/08/30
Mycoplasma hyopneumoniae
RT-qPCR
real-time quantitative polymerase chain reaction
internal reference genes
gatB
virulence