机构

• 上海药物研究所 [11]

采集方式

• OAI收割 [11]

内容类型

• 期刊论文 [11]

发表日期

• 2023 [2]
• 2022 [4]
• 2021 [3]
• 2019 [1]
• 2015 [1]

学科主题

筛选

浏览/检索结果: 共11条，第1-10条 帮助 限定条件 存缴方式：oaiharvest    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序题名升序题名降序作者升序作者降序发表日期升序发表日期降序 OTTM: an automated classification tool for translational drug discovery from omics data 期刊论文  OAI收割 BRIEFINGS IN BIOINFORMATICS, 2023, 页码: 12 作者:  Yang, Xiaobo;  Zhang, Bei;  Wang, Siqi;  Lu, Ye;  Chen, Kaixian   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/10/17 OTTM  omics data  translational drug discovery  literature mining  hepatocellular carcinoma   Discovery of novel triazine derivatives as potent retinoic acid receptor-related orphan receptor gamma t (ROR gamma t) inverse agonists 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256, 页码: 18 作者:  Lu, Lixue;  Chen, Song;  Yu, Mingcheng;  Zhou, Ronghui;  Guo, Siqi   |  收藏  |  浏览/下载：16/0  |  提交时间：2023/10/17 ROR gamma t  Triazines  Inverse agonist  Psoriasis  Autoimmune diseases   Design, synthesis, and biological evaluation of novel carbazole derivatives as potent DNMT1 inhibitors with reasonable PK properties 期刊论文  OAI收割 JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 1537-1555 作者:  Li, Ennian;  Wang, Kai;  Zhang, Bei;  Guo, Siqi;  Xiao, Senhao   |  收藏  |  浏览/下载：37/0  |  提交时间：2022/08/16 DNMT1 inhibitor  A549 cell lines  HCT116 cell lines  antitumor activity  pharmacokinetic   A 33-residue peptide tag increases solubility and stability of Escherichia coli produced single-chain antibody fragments 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 4614 作者:  Wang, Yang;  Yuan, Wenjie;  Guo, Siqi;  Li, Qiqi;  Chen, Xiaomei   |  收藏  |  浏览/下载：14/0  |  提交时间：2024/03/21 SLC1A1-mediated cellular and mitochondrial influx of R-2-hydroxyglutarate in vascular endothelial cells promotes tumor angiogenesis in IDH1-mutant solid tumors 期刊论文  OAI收割 CELL RESEARCH, 2022, 页码: 21 作者:  Wang, Xiaomin;  Chen, Ziqi;  Xu, Jun;  Tang, Shuai;  An, Nan   |  收藏  |  浏览/下载：39/0  |  提交时间：2022/06/15 High-Throughput-Methyl-Reading (HTMR) assay: a solution based on nucleotide methyl-binding proteins enables large-scale screening for DNA/RNA methyltransferases and demethylases 期刊论文  OAI收割 NUCLEIC ACIDS RESEARCH, 2022, 卷号: 50, 期号: 2, 页码: 14 作者:  Xiao, Senhao;  Guo, Siqi;  Han, Jie;  Sun, Yanli;  Wang, Mingchen   |  收藏  |  浏览/下载：29/0  |  提交时间：2022/06/15 Design, synthesis, and antibacterial evaluation of vancomycin-LPS binding peptide conjugates 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 45, 页码: 8 作者:  Shi, Weiwei;  Chen, Feifei;  Zou, Xiangman;  Jiao, Shang;  Wang, Siqi   |  收藏  |  浏览/下载：31/0  |  提交时间：2021/08/17 Vancomycin analogues  LPS binding peptides  Vancomycin-Peptide Conjugates  Antibacterial activity   Rh-Catalyzed cascade C-H activation/C-C cleavage/cyclization of carboxylic acids with cyclopropanols 期刊论文  OAI收割 CHEMICAL COMMUNICATIONS, 2021, 页码: 4 作者:  Wang, Siqi;  Miao, Erfei;  Wang, Hao;  Song, Bichao;  Huang, Wei   |  收藏  |  浏览/下载：17/0  |  提交时间：2021/08/17 Anti-PD-Ll mediating tumor-targeted codelivery of liposomal irinotecan/JQl for chemo-immunotherapy 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2021, 卷号: 42, 期号: 9, 页码: 1516 作者:  He Zhidi;  Zhang Meng;  Wang Yonghui;  He Yang;  Wang Hairui   |  收藏  |  浏览/下载：5/0  |  提交时间：2023/05/22 tumor-targeted delivery  immunogenic cell death  PD-1/PD-L1 blockade  tumor immune microenvironment  irinotecan  JQ1  immune checkpoint   Proteomics identifies new therapeutic targets of early-stage hepatocellular carcinoma 期刊论文  OAI收割 NATURE, 2019, 卷号: 567, 期号: 7747, 页码: 257-+ 作者:  Jiang, Ying;  Sun, Aihua;  Zhao, Yang;  Ying, Wantao;  Sun, Huichuan   |  收藏  |  浏览/下载：62/0  |  提交时间：2020/07/01