中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [41]
采集方式
OAI收割 [41]
内容类型
期刊论文 [41]
发表日期
2020 [41]
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浏览/检索结果:
共41条,第1-10条
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发表日期:2020
内容类型:期刊论文
专题:上海药物研究所
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Offline two-dimensional liquid chromatography coupled with ion mobility-quadrupole time-of-flight mass spectrometry enabling four-dimensional separation and characterization of the multicomponents from white ginseng and red ginseng
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2020, 卷号: 10, 期号: 6, 页码: 597-609
作者:
Zuo, Tiantian
;
Zhang, Chunxia
;
Li, Weiwei
;
Wang, Hongda
;
Hu, Ying
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2021/05/24
Dimension-enhanced strategy
Multicomponent characterization
Ginsenoside
Offline two-dimensional liquid chromatography
Ion mobility-quadrupole time-of-flight mass spectrometry
In-house database
Discovery and Optimization of Non-bile Acid FXR Agonists as Preclinical Candidates for the Treatment of Nonalcoholic Steatohepatitis
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 21, 页码: 12748-12772
作者:
Li, Junyou
;
Liu, Mengqi
;
Li, Yazhou
;
Sun, Dan-dan
;
Shu, Zhihao
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/05/24
Tu-San-Qi (Gynura japonica): the culprit behind pyrrolizidine alkaloid-induced liver injury in China
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Zhu, Lin
;
Zhang, Chun-yuan
;
Li, Dong-ping
;
Chen, Hu-biao
;
Ma, Jiang
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/12/24
herb-induced liver injury
hepatic sinusoidal obstruction syndrome
pyrrolizidine alkaloids
Tu-San-Qi
Gynura japonica
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:
Che, Jinxin
;
Huang, Feng
;
Zhang, Mengmeng
;
Xu, Gaoya
;
Qu, Bingxue
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2020/12/21
Metabolic pathways
Isocitrate dehydrogenase 2
Conformational restriction
Macrocyclic derivatives
Inhibitors
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:
Che, Jinxin
;
Huang, Feng
;
Zhang, Mengmeng
;
Xu, Gaoya
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/12/21
Metabolic pathways
Isocitrate dehydrogenase 2
Conformational restriction
Macrocyclic derivatives
Inhibitors
An electric-field-responsive paramagnetic contrast agent enhances the visualization of epileptic foci in mouse models of drug-resistant epilepsy
期刊论文
OAI收割
NATURE BIOMEDICAL ENGINEERING, 2020, 页码: 16
作者:
Wang, Cong
;
Sun, Wanbing
;
Zhang, Jun
;
Zhang, Jianping
;
Guo, Qinghua
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/12/21
A phase II randomized trial of sodium oligomannate in Alzheimer’s dementia
期刊论文
OAI收割
Alzheimer's Research & Therapy, 2020, 卷号: 12, 期号: 1
作者:
Wang,Tao
;
Kuang,Weihong
;
Chen,Wei
;
Xu,Wenwei
;
Zhang,Liming
  |  
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2020/12/24
Sodium oligomannate
Efficacy
Safety
Alzheimer’s disease
Clinical trial
A phase II randomized trial of sodium oligomannate in Alzheimer's dementia
期刊论文
OAI收割
ALZHEIMERS RESEARCH & THERAPY, 2020, 卷号: 12, 期号: 1, 页码: 10
作者:
Wang, Tao
;
Kuang, Weihong
;
Chen, Wei
;
Xu, Wenwei
;
Zhang, Liming
  |  
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2020/12/21
Sodium oligomannate
Efficacy
Safety
Alzheimer's disease
Clinical trial
Comparative Transcriptomic and Proteomic Analyses Prove that IFN-lambda 1 is a More Potent Inducer of ISGs than IFN-alpha against Porcine Epidemic Diarrhea Virus in Porcine Intestinal Epithelial Cells
期刊论文
OAI收割
JOURNAL OF PROTEOME RESEARCH, 2020, 卷号: 19, 期号: 9, 页码: 3697-3707
作者:
Zhao, Mingzhi
;
Li, Liang
;
Zhai, Linhui
;
Yue, Qi
;
Liu, Hongyu
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2020/12/21
intestinal epithelial cell
IFN-lambda 1
IFN-alpha
anti-PEDV
transcriptomics
proteomics
Original Pharmacodynamic and pharmacokinetic effects of S086, a novel angiotensin receptor neprilysin inhibitor
期刊论文
OAI收割
BIOMEDICINE & PHARMACOTHERAPY, 2020, 卷号: 129, 页码: 10
作者:
Sun, Jingchao
;
Xu, Wenjie
;
Hua, Huaijie
;
Xiao, Ying
;
Chen, Xiaoyan
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/12/24
Angiotensin receptor-NEP inhibitor
Heart failure
Neprilysin inhibitor
Angiotensin receptor blocker