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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [13]
采集方式
OAI收割 [13]
内容类型
期刊论文 [13]
发表日期
2022 [1]
2020 [1]
2018 [5]
2017 [1]
2016 [2]
2015 [2]
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Liquorice Extract and 18 beta-Glycyrrhetinic Acid Protect Against Experimental Pyrrolizidine Alkaloid-Induced Hepatotoxicity in Rats Through Inhibiting Cytochrome P450-Mediated Metabolic Activation
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 14
作者:
Wang, Zhangting
;
Ma, Jiang
;
Yao, Sheng
;
He, Yisheng
;
Miu, Kai-Kei
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/06/15
18 beta-glycyrrhetinic acid
pyrrolizidine alkaloid
cytochrome P450
metabolic activation
competitive inhibition
Tu-San-Qi (Gynura japonica): the culprit behind pyrrolizidine alkaloid-induced liver injury in China
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Zhu, Lin
;
Zhang, Chun-yuan
;
Li, Dong-ping
;
Chen, Hu-biao
;
Ma, Jiang
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/12/24
herb-induced liver injury
hepatic sinusoidal obstruction syndrome
pyrrolizidine alkaloids
Tu-San-Qi
Gynura japonica
The role of formation of pyrrole-ATP synthase subunit beta adduct in pyrrolizidine alkaloid-induced hepatotoxicity
期刊论文
OAI收割
ARCHIVES OF TOXICOLOGY, 2018, 卷号: 92, 期号: 11, 页码: 3403-3414
作者:
Lu, Yao
;
Ma, Jiang
;
Song, Zijing
;
Ye, Yang
;
Fu, Peter P.
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
Pyrrolizidine alkaloid
Retrorsine
ATP5B
Mitochondrial damage
Pyrrole-protein adduct
Gynura Rhizoma containing pyrrolizidine alkaloids induces the hepatic sinusoidal obstruction syndrome in mice via upregulating fibrosis-related factors
期刊论文
OAI收割
Acta pharmacologica Sinica, 2018
作者:
Zhang, Fang
;
Zhou, Yue
;
Yang, Xiao
;
Xiong, Ai-Zhen
;
Wang, Zheng-Tao
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
Liquiritigenin and liquiritin alleviated MCT-induced HSOS by activating Nrf2 antioxidative defense system
期刊论文
OAI收割
Toxicology and applied pharmacology, 2018, 卷号: 355, 页码: 18-27
作者:
Huang, Zhenlin
;
Sheng, Yuchen
;
Chen, Minwei
;
Hao, Zhanxia
;
Hu, Feifei
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
Pyrrole-protein adducts - A biomarker of pyrrolizidine alkaloid-induced hepatotoxicity
期刊论文
OAI收割
JOURNAL OF FOOD AND DRUG ANALYSIS, 2018, 卷号: 26, 期号: 3, 页码: 965-972
作者:
Ma, Jiang
;
Xia, Qingsu
;
Fu, Peter P.
;
Lin, Ge
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2019/01/08
Pyrrolizidine alkaloids
Pyrrole-protein adducts
Covalent binding
Target protein
Mechanism-based biomarker
Clinical diagnosis
The involvement of Nrf2 antioxidant signalling pathway in the protection of monocrotaline-induced hepatic sinusoidal obstruction syndrome in rats by (+)-catechin hydrate
期刊论文
OAI收割
Free radical research, 2018, 卷号: 52, 期号: 4, 页码: 402-414
作者:
Jing, Xiaoqi
;
Zhang, Jiaqi
;
Huang, Zhenlin
;
Sheng, Yuchen
;
Ji, Lili
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
First evidence of pyrrolizidine alkaloid N-oxide-induced hepatic sinusoidal obstruction syndrome in humans
期刊论文
OAI收割
ARCHIVES OF TOXICOLOGY, 2017, 卷号: 91, 期号: 12, 页码: 3913-3925
作者:
Yang, Mengbi
;
Ruan, Jianqing
;
Gao, Hong
;
Li, Na
;
Ma, Jiang
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
Pyrrolizidine alkaloid N-oxide
Pyrrolizidine alkaloid
Hepatic sinusoidal obstruction syndrome
Pyrrole-protein adduct
Biotransformation
Toxicokinetic
Chlorogenic acid suppresses monocrotaline-induced sinusoidal obstruction syndrome: The potential contribution of NFκB, Egr1, Nrf2, MAPKs and PI3K signals
期刊论文
OAI收割
Environmental toxicology and pharmacology, 2016, 卷号: 46, 页码: 80-89
作者:
Zheng, Zhiyong
;
Shi, Liang
;
Sheng, Yuchen
;
Zhang, Jiaqi
;
Lu, Bin
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Cytotoxicity of pyrrolizidine alkaloid in human hepatic parenchymal and sinusoidal endothelial cells: Firm evidence for the reactive metabolites mediated pyrrolizidine alkaloid-induced hepatotoxicity
期刊论文
OAI收割
Chemico-biological interactions, 2016, 卷号: 243, 页码: 119-26
作者:
Yang, Mengbi
;
Ruan, Jianqing
;
Fu, Peter P
;
Lin, Ge
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08