中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [9]
采集方式
OAI收割 [9]
内容类型
期刊论文 [9]
发表日期
2020 [9]
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发表日期:2020
专题:上海药物研究所
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Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Zhang, Xiao-tuan
;
Hu, Xiao-bei
;
Wang, Han-lin
;
Kan, Wei-juan
;
Xu, Lei
  |  
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2020/12/24
DLBCL
BTK inhibitor
ibrutinib resistance
UPR
TUDCA
2-DG
Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Su, Hai-xia
;
Yao, Sheng
;
Zhao, Wen-feng
;
Li, Min-jun
;
Liu, Jia
  |  
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2020/12/24
SARS-CoV-2
3CL protease
traditional Chinese medicines
Shuanghuanglian oral liquid
baicalin
baicalein
Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet-induced hepatic steatosis and insulin resistance by elevating IL-18 levels
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 31, 页码: 10842-10856
作者:
Liu, Wen
;
Yin, Ye
;
Wang, Meijing
  |  
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2020/12/24
Src homology 2 domain containing tyrosine phosphatase-2 (SHP2)
hepatic steatosis
insulin resistance
caspase-1
interleukin 18 (IL-18)
fatty liver
metabolic disorder
inflammation
cytokine signaling
caspase 1 (CASP1)
tyrosine-protein phosphatase (tyrosine phosphatase)
macrophage
Synthesis and biological evaluation of heterocyclic bis-aryl amides as novel Src homology 2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 11, 页码: 5
作者:
Satheeshkumar, Rajendran
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/07/01
Heterocyclic bis-aryl amides
PTP1B
SHP2
Inhibitors
Structure-activity relationships (SAR)
Active constituents and mechanisms of Respiratory Detox Shot, a traditional Chinese medicine prescription, for COVID-19 control and prevention: Network -molecular docking-LC-MSE analysis
期刊论文
OAI收割
JOURNAL OF INTEGRATIVE MEDICINE-JIM, 2020, 卷号: 18, 期号: 3, 页码: 229-241
作者:
Zhang, Zi-jia
;
Wu, Wen-yong
;
Hou, Jin-jun
;
Zhang, Lin-lin
;
Li, Fei-fei
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2020/07/01
Lung-toxin Dispelling Formula No. 1
COVID-19
3C-like protease
Network pharmacology
Molecular docking
Meridian tropism
Heterogeneous immunogenomic features and distinct escape mechanisms in multifocal hepatocellular carcinoma
期刊论文
OAI收割
JOURNAL OF HEPATOLOGY, 2020, 卷号: 72, 期号: 5, 页码: 896-908
作者:
Dong, Liang-qing
;
Peng, Li-hua
;
Ma, Li-jie
;
Liu, Dong-bing
;
Zhang, Shu
  |  
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2020/07/01
Hepatocellular carcinoma
Tumor heterogeneity
Tumor microenvironment
Immunoediting
Neoantigen
Supramolecular Prodrug Nanovectors for Active Tumor Targeting and Combination Immunotherapy of Colorectal Cancer
期刊论文
OAI收割
ADVANCED SCIENCE, 2020, 页码: 14
作者:
Hu, Xianli
;
Hou, Bo
;
Xu, Zhiai
;
Saeed, Madiha
;
Sun, Fang
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
active tumor targeting
cancer management
colorectal cancer
combination immunotherapy
photodynamic immunotherapy
prodrugs
supramolecular nanovectors
Synthesis and Target Identification of Benzoxepane Derivatives as Potential Anti-Neuroinflammatory Agents for Ischemic Stroke
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 卷号: 59, 期号: 6, 页码: 2429-2439
作者:
Gao, Cheng-Long
;
Hou, Gui-Ge
;
Liu, Jin
;
Ru, Tong
;
Xu, Ya-Zhou
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
anti-inflammatory
drug discovery
heterocycles
photoaffinity labeling
proteins
Design, Synthesis, and In Vitro Evaluation of Benzofuro[3,2-c]Quinoline Derivatives as Potential Antileukemia Agents
期刊论文
OAI收割
MOLECULES, 2020, 卷号: 25, 期号: 1, 页码: 13
作者:
Lin, Ying
;
Xing, Dong
;
Wu, Wen-Biao
;
Xu, Gao-Ya
;
Yu, Li-Fang
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
benzofuro[3,2-c]quinolines
3-(2-methoxyphenyl)quinolin-4(1H)one
MV-4-11 cell line
antileukemia activity