中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [13]
采集方式
OAI收割 [13]
内容类型
期刊论文 [13]
发表日期
2021 [13]
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发表日期:2021
内容类型:期刊论文
专题:上海药物研究所
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Requirments for primary human hepatocyte
期刊论文
OAI收割
CELL PROLIFERATION, 2021, 页码: 6
作者:
Peng, Zhaoliang
;
Wu, Jiaying
;
Hu, Shijun
;
Ma, Aijin
;
Wang, Lei
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2022/06/15
primary human hepatocyte
quality control
standard
GADD45 beta stabilized by direct interaction with HSP72 ameliorates insulin resistance and lipid accumulation
期刊论文
OAI收割
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 173, 页码: 11
作者:
Dong, Yunxia
;
Ma, Ningning
;
Fan, Lei
;
Yuan, Luyang
;
Wu, Qian
  |  
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2021/12/16
Non-alcoholic fatty liver disease
GADD45 beta
HSP72
Lipid accumulation
Insulin resistance
Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15069-15090
作者:
Jin, Tingting
;
Xu, Lei
;
Wang, Peipei
;
Hu, Xiaobei
;
Zhang, Runyuan
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/01/04
Solidification of volatile D-Limonene by cyclodextrin metal-organic framework for pulmonary delivery via dry powder inhalers: In vitro and in vivo evaluation
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2021, 卷号: 606, 页码: 9
作者:
Zhou, Yong
;
Zhang, Meijuan
;
Wang, Caifen
;
Ren, Xiaohong
;
Guo, Tao
  |  
收藏
  |  
浏览/下载:120/0
  |  
提交时间:2021/11/04
D-Limonene
gamma-cyclodextrin metal-organic framework
Dry powder inhaler
Solidification
Aerosolization
Bioavailability
Allicin inclusions with alpha-cyclodextrin effectively masking its odor: Preparation, characterization, and olfactory and gustatory evaluation
期刊论文
OAI收割
JOURNAL OF FOOD SCIENCE, 2021, 页码: 11
作者:
Zhou, Yong
;
Feng, Jing
;
Peng, Hui
;
Guo, Tao
;
Xiao, Jian
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/11/04
allicin
inclusion complex
odor masking
stability
alpha-cyclodextrin
Simultaneous Quantification of Four Compounds in Rat Plasma by HPLC-MS/MS and Its Application to Pharmacokinetic Study after Oral Administration of Pomegranate Flowers
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHIC SCIENCE, 2021, 页码: 9
作者:
Yisimayili, Zainaipuguli
;
Tian, Qiang
;
Xie, Yang
;
Hu, Pei
;
Abdulla, Rahima
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/06/15
Furmonertinib (Alflutinib, AST2818) is a potential positive control drug comparable to rifampin for evaluation of CYP3A4 induction in sandwich-cultured primary human hepatocytes
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Wu, Ya-li
;
Xue, Ya-ru
;
Guo, Zi-tao
;
Chen, Zhen-dong
;
Ge, Xin-yu
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/08/17
furmonertinib (alflutinib
AST2818)
quantitative proteomics
sandwich-cultured human hepatocytes
Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Jiang, Kai-long
;
Tong, Le-xian
;
Wang, Tao
;
Wang, Han-lin
;
Hu, Xiao-bei
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/05/24
CHK1 inhibitors
PY34
drug sensitivity
c-Myc
hematologic malignancies
A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia
期刊论文
OAI收割
Alzheimer's Research & Therapy, 2021, 卷号: 13, 期号: 1
作者:
Xiao,Shifu
;
Chan,Piu
;
Wang,Tao
;
Hong,Zhen
;
Wang,Shuzhen
  |  
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2021/05/24
Sodium oligomannate
Efficacy
Safety
Alzheimer’s disease
Clinical trial
Design, Synthesis, and Biological Evaluation of Orally Bioavailable CHK1 Inhibitors Active against Acute Myeloid Leukemia
期刊论文
OAI收割
CHEMMEDCHEM, 2021, 页码: 12
作者:
Jin, Tingting
;
Wang, Peipei
;
Long, Xiubing
;
Jiang, Kailong
;
Song, Pinrao
  |  
收藏
  |  
浏览/下载:126/0
  |  
提交时间:2021/05/24
CHK1 inhibitor
diaminopyrimidine
DNA damage response
oral bioavailability