中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [11]
采集方式
OAI收割 [11]
内容类型
期刊论文 [11]
发表日期
2022 [11]
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发表日期:2022
专题:上海药物研究所
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Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia
期刊论文
OAI收割
CELL RESEARCH, 2022, 页码: 19
作者:
Hu, Cheng-Long
;
Chen, Bing-Yi
;
Li, Zijuan
;
Yang, Tianbiao
;
Xu, Chun-Hui
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2022/12/13
Parthenolide reveals an allosteric mode to inhibit the deISGylation activity of SARS-CoV-2 papain-like protease
期刊论文
OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2022, 卷号: 54, 期号: 8, 页码: 1133-1139
作者:
Zou, Zhihui
;
Shan, Huizhuang
;
Sun, Demeng
;
Xia, Li
;
Shi, Yulong
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2022/11/11
COVID-19
SARS-CoV-2
PLpro
Parthenolide
deISGylation
A Traceless Site-Specific Conjugation on Native Antibodies Enables Efficient One-Step Payload Assembly
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 页码: 11
作者:
Zeng, Yue
;
Shi, Wei
;
Dong, Qian
;
Li, Wanzhen
;
Zhang, Jianxin
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2022/08/30
Acyl Transfer
Anti-Tumor
One-Step Synthesis
Site-Specific ADCs
Thioester
Discovery and biological evaluation of dispirocyclic and polycyclic ent-clerodane dimers from Isodon scoparius as novel inhibitors of Toll-like receptor signaling
期刊论文
OAI收割
ORGANIC CHEMISTRY FRONTIERS, 2022, 页码: 11
作者:
Li, Xing-Ren
;
Chen, Li
;
Hu, Kun
;
Yan, Bing-Chao
;
Du, Xue
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/08/16
Preclinical validation and phase I trial of 4-hydroxysalicylanilide, targeting ribonucleotide reductase mediated dNTP synthesis in multiple myeloma
期刊论文
OAI收割
Journal of Biomedical Science, 2022, 卷号: 29, 期号: 1
作者:
Xie,Yongsheng
;
Wang,Yingcong
;
Xu,Zhijian
;
Lu,Yumeng
;
Song,Dongliang
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/06/15
4-Hydroxysalicylanilid
Ribonucleotide reductase
Deoxyribonucleotides
DNA damage repair
Multiple myeloma
Alpinia hainanensis Rhizome Extract Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis: Active Ingredient Investigation and Evaluation
期刊论文
OAI收割
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2022, 卷号: 70, 期号: 13, 页码: 3989-3999
作者:
Ji, Kai-Long
;
Wu, Meng-Zhen
;
Huang, Chao-Ying
;
Gongpan, Pian-Chou
;
Sun, Peng
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2022/06/15
Alpinia hainanensis
anti-inflammatory effect
ulcerative colitis
curcumin-butyrovanillone hybrids
NF-kappa B signaling pathway
Self-developed NF-kappa B inhibitor 270 protects against LPS-induced acute kidney injury and lung injury through improving inflammation
期刊论文
OAI收割
BIOMEDICINE & PHARMACOTHERAPY, 2022, 卷号: 147, 页码: 12
作者:
Yu, Yan-yan
;
Li, Xiang-qian
;
Hu, Wen-peng
;
Cu, Shi-chao
;
Dai, Jia-jia
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/06/15
AKI
ALI
Inflammation
NF-kappa B inhibitor 270
A novel hybrid scan approach enabling the ion-mobility separation and the alternate data-dependent and data-independent acquisitions (HDDIDDA): Its combination with off-line two-dimensional liquid chromatography for comprehensively characterizing the multicomponents from Compound Danshen Dripping Pill
期刊论文
OAI收割
ANALYTICA CHIMICA ACTA, 2022, 卷号: 1193, 页码: 12
作者:
Wang, Hong-da
;
Wang, Hui-min
;
Wang, Xiang-yang
;
Xu, Xiao-yan
;
Hu, Ying
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2022/08/16
Alternate data-independent and data-dependent acquisition
Ion mobility/quadrupole time-of-flight mass spectrometry
Off-line two-dimensional liquid chromatography
Multicomponent characterization
Compound Danshen dripping pill
Discovery of seneciobipyrrolidine derivatives for the amelioration of glucose homeostasis disorders through 4E-BP1/Akt/AMPK signaling activation
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 228, 页码: 25
作者:
Che, Jinxin
;
Ma, Canliang
;
Lu, Jialiang
;
Chen, Binhui
;
Shi, Qiuqiu
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2022/06/15
Seneciobipyrrolidine
Phenotypic screening
Glucose homeostasis
Proteomic analysis
L6 myotubes
4E-BP1
Preclinical evaluation of [Tc-99m]Tc-labeled anti-EpCAM nanobody for EpCAM receptor expression imaging by immuno-SPECT/CT
期刊论文
OAI收割
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2022, 页码: 12
作者:
Liu, Tianyu
;
Wu, Yue
;
Shi, Linqing
;
Li, Liqiang
;
Hu, Biao
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/06/15
Immuno-SPECT/CT
EpCAM imaging
[Tc-99m]Tc-Nanobody
Site-specific radiolabeling