中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [10]
采集方式
OAI收割 [10]
内容类型
期刊论文 [10]
发表日期
2024 [10]
学科主题
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发表日期:2024
专题:上海药物研究所
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Design, Synthesis, and Pharmacological Evaluation of Spiro[carbazole-3,3′-pyrrolidine] Derivatives as cGAS Inhibitors for Treatment of Acute Lung Injury
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 24
作者:
Chen, Mingjie
;
Lei, Shuyue
;
Zhou, Zihua
;
Wang, Meng
;
Feng, Chunlan
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
Tumor-targeted PROTAC prodrug nanoplatform enables precise protein degradation and combination cancer therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 12
作者:
Zou, Zhi-feng
;
Yang, Lei
;
Nie, Hui-jun
;
Gao, Jing
;
Lei, Shu-min
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
proteolysis-targeting chimeras
tumor-targeted delivery
precise protein degradation
combination therapy
triple-negative breast cancer
RIPK1 inhibitor ameliorates pulmonary injury by modulating the function of neutrophils and vascular endothelial cells
期刊论文
OAI收割
CELL DEATH DISCOVERY, 2024, 卷号: 10, 期号: 1, 页码: 12
作者:
Yang, Tao
;
Xiang, Cai-gui
;
Wang, Xiao-han
;
Li, Qing-qing
;
Lei, Shu-yue
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/05/07
Characterization of diverse lysine acylations in
Bacillus thuringiensis
: Substrate profiling and functional exploration
期刊论文
OAI收割
PROTEOMICS, 2024, 页码: 13
作者:
Liu, Tianxian
;
Zhang, Mingya
;
Fan, Yameng
;
Zhao, Lei
;
Huang, Dan
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Bacillus thuringiensis
conservative analysis in various species
lysine acylation
regulatory mechanism
substrate characterization
Energy preservation for skeletal muscles: Shenqi Fuzheng injection prevents tissue wasting and restores bioenergetic profiles in a mouse model of chemotherapy-induced cachexia
期刊论文
OAI收割
PHYTOMEDICINE, 2024, 卷号: 125, 页码: 13
作者:
Li, Wei
;
Zhang, Zijia
;
Berik, Entezar
;
Liu, Yawen
;
Pei, Wenqiang
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/04/09
Shenqi Fuzheng injection
Chemotherapy-induce cachexia
Bioenergetic profiles
Glycolysis
TCA cycle
lipid metabolism
DRAK2 suppresses autophagy by phosphorylating ULK1 at Ser
56
to diminish pancreatic β cell function upon overnutrition
期刊论文
OAI收割
SCIENCE TRANSLATIONAL MEDICINE, 2024, 卷号: 16, 期号: 733, 页码: 16
作者:
Lu, Yuting
;
Xu, Junyu
;
Li, Yufeng
;
Wang, Ruoran
;
Dai, Chengqiu
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/03/13
New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9
作者:
Zheng, Yingying
;
Lu, Li
;
Li, Mengyue
;
Xu, Dehua
;
Zhang, Laishun
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/26
Chromone
Thiazolidine-2
4-dione
Protein tyrosine phosphatase 1B
Inhibitors
Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 16
作者:
Sun, Yaoliang
;
Chen, Zhiwen
;
Liu, Guobin
;
Chen, Xiaoai
;
Shi, Zihan
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/25
Inhibitor
Cancer
Threonine tyrosine kinase (TTK)
Covalent
Design, synthesis and biological evaluation of betulinic acid derivatives as potential inhibitors of 3CL-protease of SARS-CoV-2
期刊论文
OAI收割
STEROIDS, 2024, 卷号: 202, 页码: 8
作者:
Liu, Yaowen
;
Nie, Tianqing
;
Hou, Jinjun
;
Long, Huali
;
Zhang, Zijia
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/03/13
3CLpro
SARS-CoV-2
Betulinic acid
Natural product
Inhibitory activity
Comprehensive analysis of phenylpropanoids and butylidenephthalides in
Angelica sinensis
(Oliv.) Diels from different regions and processing methods by high-performance liquid chromatography combined with chemometrics
期刊论文
OAI收割
EUROPEAN FOOD RESEARCH AND TECHNOLOGY, 2024, 页码: 16
作者:
Sun, Yan
;
Zhou, Jing
;
Hu, Yuxin
;
Chen, Sihan
;
Ni, Hui
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/02/27
Angelicae Sinensis radix
Origin
Chemometrics
Fingerprints
Single standard to determine the multi-components