中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [253]
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OAI收割 [253]
内容类型
期刊论文 [253]
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2024 [9]
2023 [41]
2022 [28]
2021 [29]
2020 [18]
2019 [18]
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共253条,第1-10条
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内容类型:期刊论文
专题:上海药物研究所
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Structurally diverse terpenoids and their DRAK2 inhibitory activities: A follow-up study on the vulnerable conifer Pseudotsuga forrestii
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1305, 页码: 13
作者:
Zhou, Peng-Jun
;
Huang, Ting
;
Ma, Guang-Lei
;
Zhao, Ze-Yu
;
Jiang, Zhe-Lu
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/05/07
Pseudotsuga forrestii
Rare and endangered plants (REPs)
Triterpene-monoterpene hybrids
GLMDs
DRAK2 inhibition
Molecular docking
Discovery and Optimization of Novel Nonbile Acid FXR Agonists as Preclinical Candidates for the Treatment of Inflammatory Bowel Disease
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 7, 页码: 5642-5661
作者:
Li, Yuan
;
Xu, Tingting
;
Zhao, Yue
;
Zhang, Hui
;
Liu, Zesheng
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/05/07
Discovery of potent PROTAC degraders of Pin1 for the treatment of acute myeloid leukemia
期刊论文
OAI收割
CHEMICAL SCIENCE, 2024, 卷号: 15, 期号: 13, 页码: 5027-5035
作者:
Shi, Yunkai
;
Liu, Minmin
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/05/07
Identification of a Novel Selective CDK9 Inhibitor for the Treatment of CRC: Design, Synthesis, and Biological Activity Evaluation
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 6, 页码: 4739-4756
作者:
Zhong, Ye
;
Xu, Jing
;
Zhou, Ruochen
;
Tang, Li
;
Ding, Shaoyue
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/05/07
7-Dehydrocholesterol dictates ferroptosis sensitivity
期刊论文
OAI收割
NATURE, 2024, 卷号: 626, 期号: 7998, 页码: 29
作者:
Li, Yaxu
;
Ran, Qiao
;
Duan, Qiuhui
;
Jin, Jiali
;
Wang, Yanjin
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/04/09
Novel imidazo[1,2,4] triazole derivatives: Synthesis, fluorescence, bioactivity for SHP1
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 15
作者:
Yan, Xue
;
Zhang, Chun
;
Gao, Li-Xin
;
Liu, Min -Min
;
Yang, Yu-Ting
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/27
Imidazo[124] triazole derivatives
Fluorescence property
SHP1
Bioactivity
Cellular imaging
New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9
作者:
Zheng, Yingying
;
Lu, Li
;
Li, Mengyue
;
Xu, Dehua
;
Zhang, Laishun
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/26
Chromone
Thiazolidine-2
4-dione
Protein tyrosine phosphatase 1B
Inhibitors
A novel pterostilbene compound DCZ0825 induces macrophage M1 differentiation and Th1 polarization to exert anti-myeloma and immunomodulatory
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2024, 卷号: 127, 页码: 14
作者:
Zhang, Hui
;
Hu, Ke
;
Lu, Yumeng
;
Xu, Zhijian
;
Chen, Gege
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/25
Multiple myeloma
M1 macrophages
Th1 cells
Immunomodulatory
Species discrimination of multiple botanical origins of
Fritillaria
species based on infrared spectroscopy, thin layer chromatography-image analysis and untargeted metabolomics
期刊论文
OAI收割
PHYTOMEDICINE, 2024, 卷号: 123, 页码: 11
作者:
An, Ya-Ling
;
Li, Yun
;
Wei, Wen-Long
;
Li, Zhen-Wei
;
Zhang, Jian-Qing
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/26
Species discrimination
Fritillaria species
Infrared spectroscopy
Thin layer chromatography-image analysis
Untargeted metabolomics
Epigenetic-based combination therapy and liposomal codelivery overcomes osimertinib-resistant NSCLC via repolarizing tumor-associated macrophages
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:
Lin, Ting-ting
;
Xiong, Wei
;
Chen, Gui-hua
;
He, Yang
;
Long, Li
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/26
osimertinib resistance
targeted drug delivery
liposomes
panobinostat
tumor-associated macrophage
combination therapy