机构

• 上海药物研究所 [13]
• 南海海洋研究所 [1]
• 植物研究所 [1]

采集方式

• OAI收割 [15]

内容类型

• 期刊论文 [13]
• 学位论文 [2]

发表日期

• 2024 [1]
• 2021 [3]
• 2020 [1]
• 2019 [1]
• 2017 [1]
• 2016 [4]
• 更多

学科主题

筛选

浏览/检索结果: 共15条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Novel imidazo[1,2,4] triazole derivatives: Synthesis, fluorescence, bioactivity for SHP1 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 15 作者:  Yan, Xue;  Zhang, Chun;  Gao, Li-Xin;  Liu, Min -Min;  Yang, Yu-Ting   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/02/27 Imidazo[124] triazole derivatives  Fluorescence property  SHP1  Bioactivity  Cellular imaging   Theoretical study and application of 2-phenyl-1,3,4-thiadiazole derivatives with optical and inhibitory activity against SHP1 期刊论文  OAI收割 PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2021, 页码: 14 作者:  Zhang, Chun;  Sun, Yi-Tao;  Gao, Li-Xin;  Feng, Bo;  Yan, Xue   |  收藏  |  浏览/下载：47/0  |  提交时间：2022/01/18 Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13 作者:  Meng, Xiang-Dong;  Gao, Li-Xin;  Wang, Zhi-Jia;  Feng, Bo;  Zhang, Chun   |  收藏  |  浏览/下载：61/0  |  提交时间：2021/12/01 2,5-diphenyl-1,3,4-oxadiazole derivatives  SHP2  Inhibitors  Structure-activity relationships (SAR)   Synthesis of 5-Phenyl-1,3,4-thiadiazole Derivatives and Their Biochemical Evaluation against Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase 1 (SHP1) 期刊论文  OAI收割 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 8, 页码: 3097-3105 作者:  Yu Lijie;  Feng Bo;  Wang Zhijia;  Gao Lixin;  Zhang Chun   |  收藏  |  浏览/下载：94/0  |  提交时间：2021/11/04 5-phenyl-1,3,4-thiadiazole derivatives  Src homology 2 domain-containing protein tyrosine phosphatase 1 (SHP1)  inhibitors  structure-activity relationships   Synthesis and biological evaluation of heterocyclic bis-aryl amides as novel Src homology 2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 11, 页码: 5 作者:  Satheeshkumar, Rajendran;  Zhu, Rui;  Feng, Bo;  Huang, Chao;  Gao, Ya   |  收藏  |  浏览/下载：38/0  |  提交时间：2020/07/01 Heterocyclic bis-aryl amides  PTP1B  SHP2  Inhibitors  Structure-activity relationships (SAR)   三株深海沉积物与珊瑚来源真菌的次生代谢产物及其生物活性研究 学位论文  OAI收割 : 南海海洋研究所, 2019 作者:  梁潇   |  收藏  |  浏览/下载：65/0  |  提交时间：2020/09/04 深海沉积物来源真菌，珊瑚来源真菌，次生代谢产物，生物活性   Benzo[c][1,2,5] thiadiazole derivatives: A new class of potent Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 23, 页码: 5154-5157 作者:  Wang, Wen-Long;  Chen, Xiao-Yu;  Gao, Ya;  Gao, Li-Xin;  Sheng, Li   |  收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 Benzo[c][1,2,5] thiadiazole derivatives  PTP1B  SHP2  Inhibitors  Structure-activity relationships (SAR)   芳酰胺类衍生物的合成及蛋白酪氨酸磷酸酶1B和含SH2结构域蛋白酪氨酸磷酸酶2抑制活性研究 期刊论文  OAI收割 有机化学, 2016, 卷号: 36, 期号: 09, 页码: 2142-2149 作者:  王文龙;  骆欢;  高雅;  高立信;  盛丽   |  收藏  |  浏览/下载：14/0  |  提交时间：2019/01/08 PTP1B  SHP2  芳酰胺衍生物  抑制剂   Synthesis of Aromatic Amide Derivatives and Their Biological Evaluation against Protein Tyrosine Phosphatase 1B and Scr Homology-2 Domain Containing Protein Tyrosine Phosphatase-2 期刊论文  OAI收割 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2016, 卷号: 36, 期号: 9, 页码: 2142-2149 作者:  Wang Wenlong;  Luo Huan;  Gao Ya;  Gao Lixin;  Sheng Li   |  收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 PTP1B  SHP2  aromatic amide derivatives  inhibitors   Design, synthesis and in vitro activity of phidianidine B derivatives as novel PTP1B inhibitors with specific selectivity 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 3, 页码: 778-781 作者:  Zhang, Li;  Jiang, Cheng-Shi;  Gao, Li-Xin;  Gong, Jing-Xu;  Wang, Zhong-Hua   |  收藏  |  浏览/下载：14/0  |  提交时间：2019/01/08 Phidianidine  Oxadiazole derivative  PTP1B inhibitor  Specific selectivity  Docking analysis  Function-oriented synthesis