机构

• 上海药物研究所 [7]

采集方式

• OAI收割 [7]

内容类型

• 期刊论文 [7]

发表日期

• 2023 [2]
• 2022 [1]
• 2019 [1]
• 2018 [1]
• 2017 [2]

学科主题

筛选

浏览/检索结果: 共7条，第1-7条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序题名升序题名降序作者升序作者降序发表日期升序发表日期降序 A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割 EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9 作者:  Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/11 COVID-19  Simnotrelvir  Safety  Pharmacokinetics  Healthy subjects   The PIWI-specific insertion module helps load longer piRNAs for translational activation essential for male fertility 期刊论文  OAI收割 SCIENCE CHINA-LIFE SCIENCES, 2023, 页码: 23 作者:  Wang, Xin;  Lin, Di-Hang;  Yan, Yue;  Wang, An-Hui;  Liao, Jiaoyang   |  收藏  |  浏览/下载：26/0  |  提交时间：2023/10/17 PIWI  piRNAs  PIWI-Ins  translational activation  spermatid development  male fertility   Eugenol restrains abdominal aortic aneurysm progression with down-regulations on NF-kappa B and COX-2 期刊论文  OAI收割 PHYTOTHERAPY RESEARCH, 2022, 卷号: 36, 期号: 2, 页码: 928-937 作者:  Zhai, Ziyi;  Zhang, Xianjing;  Ding, Yuchao;  Huang, Ziming;  Li, Qian   |  收藏  |  浏览/下载：25/0  |  提交时间：2022/06/15 abdominal aortic aneurysm  COX-2  eugenol  NF-kappa B   Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070 作者:  Xiao, Li;  Wang, Yujun;  Zhang, Mumei;  Wu, Weiwei;  Kong, Linghui   |  收藏  |  浏览/下载：81/0  |  提交时间：2020/07/01 7 beta-Methyl substituent is a structural locus associated with activity cliff for nepenthone analogues 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 14, 页码: 4254-4263 作者:  Sun, Hui-jiao;  Wang, Yu-hua;  Yuan, Cong-min;  Kong, Ling-hui;  Xu, Xue-jun   |  收藏  |  浏览/下载：80/0  |  提交时间：2019/01/08 7 beta-Methyl-nepenthone analogues  KOR ligands  Concept of hybridization  Opioid receptor binding and functional activities   Discovery of alkyl bis(oxy)dibenzimidamide derivatives as novel protein arginine methyltransferase 1 (PRMT1) inhibitors 期刊论文  OAI收割 CHEMICAL BIOLOGY & DRUG DESIGN, 2017, 卷号: 90, 期号: 6, 页码: 1260-1270 作者:  Zhang, Wei-yao;  Lu, Wen-chao;  Jiang, Hao;  Lv, Zheng-bing   |  收藏  |  浏览/下载：32/0  |  提交时间：2019/01/08 epigenetics  molecular docking  PRMT1  scaffold hopping  small-molecule inhibitor   Multiple Dose Pharmacokinetics and Safety of Sulcardine Sulfate in Healthy Chinese Male Subjects: An Open-Label Phase I Clinical Study 期刊论文  OAI收割 EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, 2017, 卷号: 42, 期号: 4, 页码: 593-599 作者:  Wang, Wei;  Qian, Hong-jie;  Xin, Liang;  Zhang, Meng-qi;  Lu, Dong-ying   |  收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08