中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [8]
采集方式
OAI收割 [8]
内容类型
期刊论文 [8]
发表日期
2023 [2]
2022 [1]
2020 [1]
2015 [1]
2009 [1]
2008 [1]
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专题:上海药物研究所
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A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects
The PIWI-specific insertion module helps load longer piRNAs for translational activation essential for male fertility
期刊论文
OAI收割
SCIENCE CHINA-LIFE SCIENCES, 2023, 页码: 23
作者:
Wang, Xin
;
Lin, Di-Hang
;
Yan, Yue
;
Wang, An-Hui
;
Liao, Jiaoyang
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/10/17
PIWI
piRNAs
PIWI-Ins
translational activation
spermatid development
male fertility
Caulophyine A, a Rare Azapyrene Alkaloid from the Roots of Caulophyllum robustum
期刊论文
OAI收割
CHEMICAL & PHARMACEUTICAL BULLETIN, 2022, 卷号: 70, 期号: 4, 页码: 283-285
作者:
Wei, Wei
;
Yuan, Ya-Hong
;
Jiao, Fu-Rong
;
Zhao, Xiang
;
Xiao, Lei
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/06/15
Caulophyllum robustum
alkaloid
azapyrene
Heterogeneous immunogenomic features and distinct escape mechanisms in multifocal hepatocellular carcinoma
期刊论文
OAI收割
JOURNAL OF HEPATOLOGY, 2020, 卷号: 72, 期号: 5, 页码: 896-908
作者:
Dong, Liang-qing
;
Peng, Li-hua
;
Ma, Li-jie
;
Liu, Dong-bing
;
Zhang, Shu
  |  
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2020/07/01
Hepatocellular carcinoma
Tumor heterogeneity
Tumor microenvironment
Immunoediting
Neoantigen
In-vivo and In-vitro Metabolism Study of Timosaponin B-II Using HPLC-ESI-MS (n)
期刊论文
OAI收割
CHROMATOGRAPHIA, 2015, 卷号: 78, 期号: 17-18, 页码: 1175-1184
作者:
Jia, Yao
;
Fu, Zhiwen
;
Li, Zhixiong
;
Hu, Pei
;
Xue, Rui
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
HPLC-ESI-MSn
Timosaponin B-II
Metabolism
Tissue distribution
Antitumor Efficacy of Two Novel Non-Thiazolidinedione Compounds as Peroxisome Proliferator-Activated Receptor-gamma Agonists in Human Osteosarcoma Cells in vitro
期刊论文
OAI收割
CHEMOTHERAPY, 2009, 卷号: 55, 期号: 6, 页码: 468-476
作者:
Fu, Lili
;
Xiong, Xishan
;
Wang, Li
;
Gao, Xiang
;
Ye, Yangliang
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2019/01/08
Cytotoxicity
alpha-Aryloxy-alpha-methylhydrocinnamic acid derivative
IC50
Osteosarcoma
Peroxisome proliferator-activated receptor gamma
Anti-inflammatory effects of Z23 on LPS-induced inflammatory responses in RAW264.7 macrophages
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2008, 卷号: 120, 期号: 3, 页码: 447-451
作者:
Hu, Xu-Dong
;
Yang, Yang
;
Zhong, Xiang-Gen
;
Zhang, Xiang-Hua
;
Zhang, Yi-Nan
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Z23
Inducible nitric oxide synthase
Cyclooxygenase2
Cytokine
RAW264.7 macrophage
7 '-(3 ',4 '-dihydroxyphenyl)-N-[(4-methoxyphenyl)ethyl]propenamide (Z23), an effective compound from the Chinese herb medicine Fissistigma oldhamii (Hemsl.) Merr, suppresses T cell-mediated immunity in vitro and in vivo
期刊论文
OAI收割
LIFE SCIENCES, 2007, 卷号: 81, 期号: 25-26, 页码: 1677-1684
作者:
Hu, Xu-Dong
;
Zhong, Xiang-Gen
;
Zhang, Xiang-Hua
;
Zhang, Yi-Nan
;
Zheng, Zong-Ping
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
Z23
splenocyte proliferation
mixed lymphocyte culture reaction
delayed-type hypersensitivity
collagen-induced arthritis