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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [14]
采集方式
OAI收割 [14]
内容类型
期刊论文 [14]
发表日期
2020 [4]
2019 [1]
2018 [1]
2017 [3]
2016 [2]
2015 [1]
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专题:上海药物研究所
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Discovery of Phthalazinone Derivatives as Novel Hepatitis B Virus Capsid Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 15, 页码: 8134-8145
作者:
Chen, Wuhong
;
Liu, Feifei
;
Zhao, Qiliang
;
Ma, Xinna
;
Lu, Dong
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/12/24
The environmental stability characterization of exfoliated few-layer CrXTe3 (X = Si, Ge) nanosheets
期刊论文
OAI收割
APPLIED SURFACE SCIENCE, 2020, 卷号: 511, 页码: 6
作者:
Liu, Yun
;
Wang, Wei
;
Lu, Haoyong
;
Xie, Qiyun
;
Chen, Limin
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
CrSiTe3
CrGeTe3
Environmental stability
Raman spectra
Exfoliation, lattice vibration and air stability characterization of antiferromagnetic van der Waals NiPS3 nanosheets
期刊论文
OAI收割
APPLIED SURFACE SCIENCE, 2020, 卷号: 504, 页码: 6
作者:
Lu, Haoyong
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2020/07/01
NiPS3
Two dimensional
Magnetic van der Waals crystals
Raman spectra
A Sphingosine-1-Phosphate Modulator Ameliorates Polycystic Kidney Disease in Han:SPRD Rats
期刊论文
OAI收割
AMERICAN JOURNAL OF NEPHROLOGY, 2020, 卷号: 51, 期号: 1, 页码: 1-10
作者:
Li, Xin
;
Wu, Ming
;
Chen, Limin
;
Lu, Junyan
;
Li, Guo
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/07/01
FTY720
Sphingosine-1-phosphate
Cordyceps sinensis
Autosomal dominant polycystic kidney disease
Inflammation
Human substance P receptor binding mode of the antagonist drug aprepitant by NMR and crystallography
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 8
作者:
Chen, Shuanghong
;
Lu, Mengjie
;
Liu, Dongsheng
;
Yang, Lingyun
;
Yi, Cuiying
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
Discovery and optimization of phthalazinone derivatives as a new class of potent dengue virus inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 145, 页码: 328-337
作者:
Lu, Dong
;
Liu, Jianan
;
Zhang, Yunzhe
;
Liu, Feifei
;
Zeng, Limin
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
Phthalazinone
Dengue virus
Inhibitor
Optimization
SAR
Design, Synthesis, and Biological Evaluation of the First c-Met/HDAC Inhibitors Based on Pyridazinone Derivatives
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 8, 期号: 8, 页码: 830-834
作者:
Lu, Dong
;
Yan, Juan
;
Wang, Lang
;
Liu, Hongchun
;
Zeng, Limin
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2019/01/08
Dual c-Met/HDAC inhibitor
hybrid
designed multiple ligand (DML)
Optimization and Synthesis of Pyridazinone Derivatives as Novel Inhibitors of Hepatitis B Virus by Inducing Genome-free Capsid Formation
期刊论文
OAI收割
ACS INFECTIOUS DISEASES, 2017, 卷号: 3, 期号: 3, 页码: 199-205
作者:
Lu, Dong
;
Liu, Feifei
;
Xing, Weiqiang
;
Tong, Xiankun
;
Wang, Lang
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
pyridazinone
HBV DNA-free capsids
drug-like optimization
SAR study
lead candidate
Discovery of novel Ponatinib analogues for reducing KDR activity as potent FGFRs inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 126, 页码: 122-132
作者:
Liu, Yang
;
Peng, Xia
;
Guan, Xiaocong
;
Lu, Dong
;
Xi, Yong
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
FGFR
KDR
Inhibitor
Anticancer
Ponatinib
Identification of novel EZH2 inhibitors through pharmacophore-based virtual screening and biological assays
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 15, 页码: 3813-3817
作者:
Wu, Yunlong
;
Hu, Junchi
;
Ding, Hong
;
Chen, Limin
;
Zhang, Yuanyuan
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
EZH2
Epigenetics
PRC2
Computational drug design
Pharmacophore-based virtual screening