中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [24]
武汉物理与数学研究所 [5]
过程工程研究所 [4]
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上海神经科学研究所 [3]
沈阳应用生态研究所 [3]
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期刊论文 [48]
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2024 [2]
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A novel BODIPY-based theranostic agent for
in vivo
fluorescence imaging of cerebral Aβ and ameliorating Aβ-associated disorders in Alzheimer's disease transgenic mice
期刊论文
OAI收割
RSC MEDICINAL CHEMISTRY, 2024, 页码: 9
作者:
Zhang, Jingjing
;
Ren, Wenming
;
Liu, Xiaohui
;
Chen, Jingjing
;
Zeng, Yuteng
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
A Near-infrared Fluorescence and Positron Emission Tomography Bimodal Probe for
I
n Vivo
I
maging of Amyloid-β Species
期刊论文
OAI收割
ACS CHEMICAL NEUROSCIENCE, 2024, 卷号: 15, 期号: 3, 页码: 472-478
作者:
Fang, Daqing
;
Pan, Donghui
;
Wen, Xidan
;
Zhang, Junya
;
Yang, Min
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/03/13
A beta species
Alzheimer's disease
NIR fluorescence imaging
PET imaging
bimodalprobe
APP/PS1
ARL6IP1 mediates small-molecule-induced alleviation of Alzheimer pathology through FXR1-dependent BACE1 translation initiation
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 22, 页码: e2220148120
作者:
Zhou,Gui-Feng
;
Tang,Jing
;
Ma,Yuan-Lin
;
Fu,Xian
;
Liu,Jun-Yan
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/09
conophylline
ARL6IP1
5'UTR
FXR1
BACE1 translation
AMYLOID PRECURSOR PROTEIN
A-BETA
TRANSGENIC MICE
MOUSE MODEL
NEURODEGENERATION
EXPRESSION
REDUCTION
MEMBRANE
MEMORY
ER
Engineering of donor-acceptor-donor curcumin analogues as near-infrared fluorescent probes for in vivo imaging of amyloid-beta species
期刊论文
OAI收割
THERANOSTICS, 2022, 卷号: 12, 期号: 7, 页码: 3178-3195
作者:
Fang, Daqing
;
Wen, Xidan
;
Wang, Yuqi
;
Sun, Yidan
;
An, Ruibing
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/06/15
Alzheimer's disease
Amyloid-beta
NIR fluorescence probe
in vivo imaging
D-A-D molecules
Yeast-Based A beta 1-15 Vaccine Elicits Strong Immunogenicity and Attenuates Neuropathology and Cognitive Deficits in Alzheimer's Disease Transgenic Mice
期刊论文
OAI收割
VACCINES, 2020, 卷号: 8, 期号: 3, 页码: 13
作者:
Liu, Dong-qun
;
Lu, Shuai
;
Zhang, Lun
;
Huang, Ya-ru
;
Ji, Mei
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2021/03/29
Alzheimer's disease
beta-amyloid
active immunotherapy
yeast
vaccine
Discovery of nitazoxanide-based derivatives as autophagy activators for the treatment of Alzheimer's disease
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 4, 页码: 646-666
作者:
Li, Xiaokang
;
Lu, Jian
;
Xu, Yixiang
;
Wang, Jiaying
;
Qiu, Xiaoxia
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
Alzheimer's disease
Autophagy
Nitazoxanide
beta-amyloid
Tau protein
Polysaccharides from Lycium barbarum ameliorate amyloid pathology and cognitive functions in APP/PS1 transgenic mice
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 144, 页码: 1004-1012
作者:
Zhou, Yue
;
Duan, Yanhong
;
Huang, Shichao
;
Zhou, Xuan
;
Zhou, Lishuang
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/07/01
Lycium barbarum polysaccharides
Alzheimer's disease
Amyloid-beta
Synaptic plasticity
Neuropathology
High-resolution mapping of brain vasculature and its impairment in the hippocampus of Alzheimer's disease mice
期刊论文
OAI收割
NATIONAL SCIENCE REVIEW, 2019, 卷号: 6, 期号: 6, 页码: 1223-1238
作者:
Zhang, Xiaochuan
;
Yin, Xianzhen
;
Zhang, Jingjing
;
Li, Anan
;
Gong, Hui
  |  
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2020/07/01
Micro-Optical Sectioning Tomography
image optimization
Alzheimer's disease
impaired hippocampal vasculature
virtual vascular endoscopy
Interplay between Alzheimer's disease and global glucose metabolism revealed by the metabolic profile alterations of pancreatic tissue and serum in APP/PS1 transgenic mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1259-1268
作者:
Liu, Xia
;
Wang, Wei
;
Chen, Hua-li
;
Zhang, Hai-yan
;
Zhang, Nai-xia
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
Alzheimer's disease
type 2 diabetes
APP/PS1 transgenic mice
metabolomics
NMR
glucose metabolism dysfunctions
Nitazoxanide, an anti-parasitic drug, efficiently ameliorates learning and memory impairments in AD model mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1279-1291
作者:
Fan, Lei
;
Qiu, Xiao-xia
;
Zhu, Zhi-yuan
;
Lv, Jian-lu
;
Lu, Jian
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
Alzheimer's disease
nitazoxanide
autophagy
inflammation
APP/PS1 transgenic mice