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浏览/检索结果: 共2576条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery of novel SOS1 inhibitors using machine learning 期刊论文  OAI收割 RSC MEDICINAL CHEMISTRY, 2024, 卷号: 15, 期号: 4, 页码: 1392-1403 作者:  Duo, Lihui;  Chen, Yi;  Liu, Qiupei;  Ma, Zhangyi;  Farjudian, Amin   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/05/07 Discovery of YFJ-36: Design, Synthesis, and Antibacterial Activities of Catechol-Conjugated β-Lactams against Gram-Negative Bacteria 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 21 作者:  Liu, Fangjun;  Kou, Qunhuan;  Li, Hongyuan;  Cao, Yangzhi;  Chen, Meng   |  收藏  |  浏览/下载：0/0  |  提交时间：2024/05/22 DockingGA: enhancing targeted molecule generation using transformer neural network and genetic algorithm with docking simulation 期刊论文  OAI收割 BRIEFINGS IN FUNCTIONAL GENOMICS, 2024, 页码: 12 作者:  Gao, Changnan;  Bao, Wenjie;  Wang, Shuang;  Zheng, Jianyang;  Wang, Lulu   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/05/20 molecule generation  molecule optimization  drug discovery  deep learning  drug design  genetic algorithm   Discovery and Optimization of Novel Nonbile Acid FXR Agonists as Preclinical Candidates for the Treatment of Inflammatory Bowel Disease 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 7, 页码: 5642-5661 作者:  Li, Yuan;  Xu, Tingting;  Zhao, Yue;  Zhang, Hui;  Liu, Zesheng   |  收藏  |  浏览/下载：3/0  |  提交时间：2024/05/07 Discovery of potent PROTAC degraders of Pin1 for the treatment of acute myeloid leukemia 期刊论文  OAI收割 CHEMICAL SCIENCE, 2024, 卷号: 15, 期号: 13, 页码: 5027-5035 作者:  Shi, Yunkai;  Liu, Minmin;  Li, Mengna;  Mao, Yiwen;  Ma, Jingkun   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/05/07 Discovery of a Covalent Inhibitor Selectively Targeting the Autophosphorylation Site of c-Src Kinase 期刊论文  OAI收割 ACS CHEMICAL BIOLOGY, 2024, 页码: 12 作者:  Zhang, Huimin;  Xu, Dounan;  Huang, Hongchan;  Jiang, Hao;  Hu, Linghao   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/05/07 Design and Synthesis of Cyclolipopeptide Mimics of Dysoxylactam A and Evaluation of the Reversing Potencies against P-Glycoprotein-Mediated Multidrug Resistance 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 6, 页码: 4560-4582 作者:  Yang, Guan-Zhou;  Wang, Lei;  Gao, Kun;  Zhu, Xi;  Lou, Li-Guang   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/05/07 Impact of Halogen Bonds on Protein-Peptide Binding and Protein Structural Stability Revealed by Computational Approaches 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 11 作者:  Li, Jintian;  Zhou, Liping;  Han, Zijian;  Wu, Leyun;  Zhang, Jianfang   |  收藏  |  浏览/下载：0/0  |  提交时间：2024/05/07 A novel BODIPY-based theranostic agent for in vivo fluorescence imaging of cerebral Aβ and ameliorating Aβ-associated disorders in Alzheimer's disease transgenic mice 期刊论文  OAI收割 RSC MEDICINAL CHEMISTRY, 2024, 页码: 9 作者:  Zhang, Jingjing;  Ren, Wenming;  Liu, Xiaohui;  Chen, Jingjing;  Zeng, Yuteng   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/05/07 Chemical Space Profiling of SARS-CoV-2 PLpro Using DNA-Encoded Focused Libraries 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2024, 页码: 10 作者:  Wang, Xudong;  Zhu, Ying;  Zhao, Qingyi;  Lu, Weiwei;  Xu, Yechun   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/05/07 DNA-Encoded Focused Libraries (DEFLs)  SARS-CoV-2  Papain-like Protease  Library Design  ProteinInhibitors