中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [19]
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Comparative study of the immunomodulatory effects of different fucoidans from Saccharina japonica mediated by scavenger receptors on RAW 264.7 macrophages
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2022, 卷号: 215, 页码: 253-261
作者:
Cui, Meiyu
;
Li, Xiaohong
;
Geng, Lihua
;
Wu, Ning
;
Wang, Jing
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/08/17
Fucoidan
Saccharina japonica
Scavenger receptor
Macrophage
SR-A
CD36
LOX-1
Immunomodulatory
Euphornin L promotes lipid clearance by dual regulation of LDLR and PCSK9
期刊论文
OAI收割
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2021, 卷号: 22, 期号: 6, 页码: 9
作者:
Li, Huihui
;
Li, Jun
;
Zhang, Xianjing
;
Li, Jiaomeng
;
Xi, Cong
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2022/06/15
euphornin L
lipid-lowering activity
low density lipoprotein receptor
proprotein convertase subtilisin
kexin type 9
extracellular signal-regulated kinase protein
secretion
Oxidized Low-Density Lipoprotein Links Hypercholesterolemia and Bladder Cancer Aggressiveness by Promoting Cancer Stemness
期刊论文
OAI收割
CANCER RESEARCH, 2021, 卷号: 81, 期号: 22, 页码: 5720-5732
作者:
Yang, Lin
;
Sun, Jingya
;
Li, Meiqian
;
Long, Yiming
;
Zhang, Dianzheng
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/01/04
Polybrominated Diphenyl Ether Quinone Exposure Induces Atherosclerosis Progression via CD36-Mediated Lipid Accumulation, NLRP3 Inflammasome Activation, and Pyroptosis
期刊论文
OAI收割
CHEMICAL RESEARCH IN TOXICOLOGY, 2021, 卷号: 34, 期号: 9, 页码: 2125-2134
作者:
Wang, Yuting
;
Fang, Changyu
;
Xu, Lei
;
Yang, Bingwei
;
Song, Erqun
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2021/12/22
23,24-Dihydrocucurbitacin B promotes lipid clearance by dual transcriptional regulation of LDLR and PCSK9
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 327-335
作者:
Li, Hui-hui
;
Li, Jun
;
Zhang, Xian-jing
;
Li, Jiao-meng
;
Xi, Cong
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
23,24-dihydrocucurbitacin B
lipid-lowering agent
LDLR
PCSK9
HNF1 alpha
SREBP2
The marine-derived furanone reduces intracellular lipid accumulation in vitro by targeting LXR alpha and PPAR alpha
期刊论文
OAI收割
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2020, 卷号: 24, 期号: 6, 页码: 3384, 3398
作者:
Li, Ting
;
Hu, Shu-Mei
;
Pang, Xiao-Yan
;
Wang, Jun-Feng
;
Yin, Jia-Yu
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/09/22
acetyl-CoA carboxylase
fatty acid synthase
furanone
LXR antagonist
PPAR antagonist
PPAR alpha agonist
reverse cholesterol transport
Recent progress in the detection and treatment of atherosclerosis by nanoparticles
期刊论文
OAI收割
MATERIALS TODAY CHEMISTRY, 2020, 卷号: 17
作者:
Chen, L.
;
Jiang, Z.
;
Akakuru, O. U.
;
Yang, L.
;
Li, J.
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/12/16
MAGNETIC-RESONANCE
MRI DETECTION
MACROPHAGES
INFLAMMATION
PLAQUE
RECEPTOR
DELIVERY
LESIONS
REDUCTION
TISSUE
Design, synthesis, and biological evaluation of novel tetrahydroprotoberberine derivatives (THPBs) as proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators for the treatment of hyperlipidemia
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 6, 页码: 1216-1230
作者:
Wu, Chenglin
;
Xi, Cong
;
Tong, Junhua
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2020/07/01
PCSK9
Tetrahydroprotoberberine derivatives
Low-density lipoprotein cholesterol
Lipid-lowering
PCSK9 expression
Low-density lipoprotein receptor
Total cholesterol
Hyperlipidemia hamster
designsynthesisandbiologicalevaluationofnoveltetrahydroprotoberberinederivativesthpbsasproproteinconvertasesubtilisinkexintype9pcsk9modulatorsforthetreatmentofhyperlipidemia
期刊论文
OAI收割
actapharmaceuticasinicab, 2019, 卷号: 9, 期号: 6, 页码: 1216
作者:
Wu Chenglin
;
Xi Cong
;
Tong Junhua
;
Zhao Jing
;
Jiang Hualiang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2020/07/01
DOPAMINE D-1
BERBERINE
EXPRESSION
INHIBITORS
IDENTIFICATION
CHOLESTEROL
MUTATIONS
LDLR
PCSK9
Tetrahydroprotoberberine derivatives
Low-density lipoprotein cholesterol
Lipid-lowering
PCSK9 expression
Low-density lipoprotein receptor
Total cholesterol
Hyperlipidemia hamster
PAQR3 modulates blood cholesterol level by facilitating interaction between LDLR and PCSK9
期刊论文
OAI收割
METABOLISM-CLINICAL AND EXPERIMENTAL, 2019, 卷号: 94, 期号: -, 页码: 88-95
作者:
Huang, Meiqin
;
Zhao, Zilong
;
Cao, Qianqian
;
Wei, Siying
;
Zhao, Jingyu
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2020/12/09
Low-density lipoprotein cholesterol
LDLR
PCSK9
Endosome
Protein degradation