中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [26]
昆明植物研究所 [3]
中国科学院大学 [2]
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期刊论文 [38]
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浏览/检索结果:
共38条,第1-10条
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Identification of 3H-benzo[b] [1,4] diazepine derivatives as PPAR alpha agonists by in silico studies and biochemical evaluation
期刊论文
OAI收割
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2023, 页码: 16
作者:
Li, Yue
;
Lv, Mengjia
;
Shen, Meiling
;
Gu, Xi
;
Zhang, Li
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
NAFLD
PPAR alpha agonist
virtual screening
biochemical evaluation
Rxrs and their partner receptor genes inducing masculinization plausibly mediated by endocrine disruption in Paralichthys olivaceus
期刊论文
OAI收割
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2023, 卷号: 226, 页码: 14
作者:
Zou, Congcong
;
Wang, Lijuan
;
Shu, Chang
;
Tan, Xungang
;
Wu, Zhihao
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/02/01
Retinoid X receptors
Steroidogenesis
Sex differentiation
LG100268
Gonad
Flounder
Hepatic cytochrome P450 8B1 and cholic acid potentiate intestinal epithelial injury in colitis by suppressing intestinal stem cell renewal
期刊论文
OAI收割
CELL STEM CELL, 2022, 卷号: 29, 期号: 9, 页码: 1366-+
作者:
Chen, Li
;
Jiao, Tingying
;
Liu, Weiwei
;
Luo, Yuhong
;
Wang, Jue
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/04/10
2,2 ',4,4 '-Tetrabromodiphenyl Ether (PBDE 47) Selectively Stimulates Proatherogenic PPAR gamma Signatures in Human THP-1 Macrophages to Contribute to Foam Cell Formation
期刊论文
OAI收割
CHEMICAL RESEARCH IN TOXICOLOGY, 2022, 卷号: 35, 期号: 6, 页码: 1023-1035
作者:
Ren, Qidong
;
Xie, Xinni
;
Zhao, Chuanfang
;
Wen, Qing
;
Pan, Ruiying
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2022/11/08
ACTIVATED-RECEPTOR-GAMMA
BROMINATED FLAME RETARDANTS
ACID-BINDING PROTEIN
GENE-EXPRESSION
LIGAND-BINDING
DIPHENYL ETHERS
INDOOR DUST
EXPOSURE
CD36
ACCUMULATION
Alisol B Alleviates Hepatocyte Lipid Accumulation and Lipotoxicity via Regulating RAR alpha-PPAR gamma-CD36 Cascade and Attenuates Non-Alcoholic Steatohepatitis in Mice
期刊论文
OAI收割
NUTRIENTS, 2022, 卷号: 14, 期号: 12, 页码: 20
作者:
Zhao, Zhuohui
;
Deng, Zhen-Tao
;
Huang, Suling
;
Ning, Mengmeng
;
Feng, Ying
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/08/16
Alisol B
non-alcoholic steatohepatitis
RAR alpha
CD36
Intestinal farnesoid X receptor signaling controls hepatic fatty acid oxidation
期刊论文
OAI收割
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2022, 卷号: 1867, 期号: 2, 页码: 13
作者:
Lu, Dasheng
;
Liu, Yameng
;
Luo, Yuhong
;
Zhao, Jie
;
Feng, Chao
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2022/01/18
Fatty acid oxidation
Acylcarnitines
FXR
FGF15/19
PGC1 alpha
Transcriptomics
Metabolomics
The marine-derived furanone reduces intracellular lipid accumulation in vitro by targeting LXR alpha and PPAR alpha
期刊论文
OAI收割
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2020, 卷号: 24, 期号: 6, 页码: 3384, 3398
作者:
Li, Ting
;
Hu, Shu-Mei
;
Pang, Xiao-Yan
;
Wang, Jun-Feng
;
Yin, Jia-Yu
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/09/22
acetyl-CoA carboxylase
fatty acid synthase
furanone
LXR antagonist
PPAR antagonist
PPAR alpha agonist
reverse cholesterol transport
Hepatocyte peroxisome proliferator-activated receptor alpha regulates bile acid synthesis and transport
期刊论文
OAI收割
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2019, 期号: 10, 页码: 1396-1411
作者:
Xie, Cen
;
Takahashi, Shogo
;
Brocker, Chad N.
;
He, Shijun
;
Chen, Li
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/07/01
Peroxisome proliferator-activated receptor alpha
Wy-14,643
Bile acid homeostasis
Farnesoid X receptor
Metabolomics
The Protective Roles of PPAR alpha Activation in Triptolide-Induced Liver Injury
期刊论文
OAI收割
TOXICOLOGICAL SCIENCES, 2019, 卷号: 171, 期号: 1, 页码: 1-12
作者:
Hu, Dan-Dan
;
Zhao, Qi
;
Cheng, Yan
;
Xiao, Xue-Rong
;
Huang, Jian-Feng
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/03/26
liver injury
metabolomics
PPAR alpha
acylcarnitines
Bavachinin analogues as agonists of pan-peroxisome proliferator-activated receptors
期刊论文
OAI收割
MEDICINAL CHEMISTRY RESEARCH, 2018, 卷号: 27, 期号: 7, 页码: 1851-1862
作者:
Yi, Jingyu
;
Du, Guoxin
;
Zhao, Yuanyuan
;
Zhang, Liuqiang
;
Li, Bo
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
Bavachinin
Metabolic syndrome
PPARs
Reporter gene assaysThese authors contributed equally: Jingyu Yi, Guoxin Du